iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	TRANSFAC	miRNAMap	RAID2
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.20e-16	61.0	430	484

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 1    ekvClvCgeggedekslveCek.CrewfHpaClklsveeelpnsekwiCpkCrsk 54
           e++C++C  g+ de+sl++Ce+ Cr+++H++C+++++ee+++n+e++iCp Crsk
   Q: 430  EQMCPICLLGMLDEESLTVCEDgCRNKLHHHCMSIWAEECRRNREPLICPLCRSK 484
           69**************************************************985 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MAAAAGDRAS SSGFPGAAAA SPEAGGGGGA LQGSGAPAAG AGLLRETGSA GRERADWRRQ 60
QLRKVRSVEL DQLPEQPLFL TASPPCPSTS PSPEPADAAA GASGFQPAAG PPPPGAASRC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCAGGGCGGG ACAAGAGGTC TGCTTTCCAA AGAGAAGGCT TCGCGTCTGT CTGCAGCAGG 60
CGACAGTCCC GGGCGCCACC TGCGCTTCGG GCGCGGGCCA GGCTGGTGCG CGCCGGGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR007527--Znf_SWIM

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50089--ZF_RING_2
PS50966--ZF_SWIM

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004672--F:protein kinase activity
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002233	Ailuropoda melanoleuca	90.72	0.00e+00	2204.00
IUUC-Apl-003550	Anas platyrhynchos	69.80	5.00e-60	223.00
IUUC-Aca-004258	Anolis carolinensis	81.64	0.00e+00	1922.00
IUUC-Ame-011412	Astyanax mexicanus	70.16	0.00e+00	1689.00
IUUC-Bta-013046	Bos taurus	89.27	0.00e+00	2218.00
IUUC-Cja-019060	Callithrix jacchus	91.83	0.00e+00	2177.00
IUUC-Cfa-020837	Canis familiaris	90.80	0.00e+00	2169.00
IUUC-Cpo-022141	Cavia porcellus	91.40	0.00e+00	2234.00
IUUC-Csa-023082	Chlorocebus sabaeus	92.19	0.00e+00	2213.00
IUUC-Cho-024597	Choloepus hoffmanni	86.47	3.00e-167	583.00
IUUC-Cin-025107	Ciona intestinalis	57.07	7.00e-60	223.00
IUUC-Csv-026034	Ciona savignyi	45.64	4.00e-129	456.00
IUUC-Dre-028821	Danio rerio	70.24	0.00e+00	1715.00
IUUC-Dno-029178	Dasypus novemcinctus	89.97	0.00e+00	2261.00
IUUC-Dor-030534	Dipodomys ordii	90.78	0.00e+00	2285.00
IUUC-Ete-032843	Echinops telfairi	89.66	0.00e+00	2063.00
IUUC-Eca-033650	Equus caballus	89.98	0.00e+00	2140.00
IUUC-Fca-035802	Felis catus	89.06	0.00e+00	2246.00
IUUC-Fal-037259	Ficedula albicollis	81.99	0.00e+00	1959.00
IUUC-Gga-040810	Gallus gallus	81.84	0.00e+00	1990.00
IUUC-Ggo-045102	Gorilla gorilla	91.05	0.00e+00	2204.00
IUUC-Hsa-045671	Homo sapiens	89.30	0.00e+00	2220.00
IUUC-Itr-048840	Ictidomys tridecemlineatus	91.72	0.00e+00	1762.00
IUUC-Lch-050377	Latimeria chalumnae	74.90	0.00e+00	1672.00
IUUC-Loc-052431	Lepisosteus oculatus	73.58	0.00e+00	1798.00
IUUC-Laf-053894	Loxodonta africana	88.26	0.00e+00	2209.00
IUUC-Mcc-055263	Macaca mulatta	92.34	0.00e+00	2216.00
IUUC-Meu-056425	Macropus eugenii	72.84	0.00e+00	663.00
IUUC-Mga-060098	Meleagris gallopavo	68.16	0.00e+00	1223.00
IUUC-Mmr-061686	Microcebus murinus	83.40	0.00e+00	2101.00
IUUC-Mdo-062008	Monodelphis domestica	81.67	0.00e+00	2009.00
IUUC-Mmu-063424	Mus musculus	94.63	0.00e+00	2408.00
IUUC-Mpu-066599	Mustela putorius furo	90.26	0.00e+00	2191.00
IUUC-Mlu-067383	Myotis lucifugus	82.48	0.00e+00	1930.00
IUUC-Nle-069023	Nomascus leucogenys	91.53	0.00e+00	2167.00
IUUC-Opr-070921	Ochotona princeps	82.74	0.00e+00	1556.00
IUUC-Oan-073487	Ornithorhynchus anatinus	83.10	0.00e+00	2038.00
IUUC-Ocu-074697	Oryctolagus cuniculus	91.31	0.00e+00	2211.00
IUUC-Oga-088673	Otolemur garnettii	90.75	0.00e+00	2192.00
IUUC-Oar-089502	Ovis aries	91.08	0.00e+00	2188.00
IUUC-Ptr-090480	Pan troglodytes	89.35	0.00e+00	2218.00
IUUC-Pan-092294	Papio anubis	90.23	0.00e+00	2243.00
IUUC-Psi-093454	Pelodiscus sinensis	98.79	9.00e-140	488.00
IUUC-Pma-094215	Petromyzon marinus	62.96	5.00e-168	584.00
IUUC-Pab-097948	Pongo abelii	89.28	0.00e+00	2248.00
IUUC-Pca-101118	Procavia capensis	86.12	0.00e+00	1894.00
IUUC-Pva-102761	Pteropus vampyrus	87.18	0.00e+00	2140.00
IUUC-Sha-106698	Sarcophilus harrisii	85.01	0.00e+00	2033.00
IUUC-Sar-113569	Sorex araneus	88.24	0.00e+00	1450.00
IUUC-Ssc-115862	Sus scrofa	90.64	0.00e+00	2284.00
IUUC-Tgu-117455	Taeniopygia guttata	81.48	0.00e+00	1971.00
IUUC-Tsy-119272	Tarsius syrichta	89.76	0.00e+00	2088.00
IUUC-Tbe-127403	Tupaia belangeri	84.37	0.00e+00	1282.00
IUUC-Ttr-128576	Tursiops truncatus	89.42	0.00e+00	2096.00
IUUC-Vpa-130139	Vicugna pacos	91.61	0.00e+00	2232.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence