iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-092840

Ensembl Protein ID

ENSPANP00000003576.1

UniProt Accession

A0A096MUR0; A0A096MUR0_PAPAN

Genbank Protein ID

ENSPANP00000003576

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHZZ01081285

Gene Name

NCK1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000016777.1	ENSPANT00000015823.1	ENSPANP00000003576.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	8.60e-47	157.0	192	251

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +++vq+ly+++++nd+eL+++kGdv++viek e+d +W+k+ ++ +g  Gl+P+n+v+ ++
   Q: 192  LHVVQALYPFSSSNDEELNFEKGDVMDVIEKPENDPEWWKC-RKINGMVGLVPKNYVTVMQ 251
           689**************************************.59*************9765 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

MAEEVVVVAK FDYVAQQEQE LDIKKNERLW LLDDSKSWWR VRNSMNKTGF VPSNYVERKN 60
SARKASIVKN LKDTLGIGKV KRKPSVPDSA SPADDSFVDP GERLYDLNMP AYVKFNYMAE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAGAAG AAGTGGTGGT AGTAGCCAAA TTTGATTATG TGGCCCAACA AGAACAAGAG 60
TTGGATATCA AGAAAAATGA GAGATTATGG CTTCTGGATG ATTCTAAGTC CTGGTGGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR017304--NCK
IPR000980--SH2
IPR001452--SH3_domain

PROSITE

PS50001--SH2
PS50002--SH3

Pfam

PF00017--SH2
PF00018--SH3_1
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005911--C:cell-cell junction
GO:0005783--C:endoplasmic reticulum
GO:0000164--C:protein phosphatase type 1 complex
GO:0005840--C:ribosome
GO:0012506--C:vesicle membrane
GO:0004860--F:protein kinase inhibitor activity
GO:0007015--P:actin filament organization
GO:0048013--P:ephrin receptor signaling pathway
GO:0030032--P:lamellipodium assembly
GO:0060548--P:negative regulation of cell death
GO:1903912--P:negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
GO:0033137--P:negative regulation of peptidyl-serine phosphorylation
GO:1903898--P:negative regulation of PERK-mediated unfolded protein response
GO:1990441--P:negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
GO:0070262--P:peptidyl-serine dephosphorylation
GO:0030838--P:positive regulation of actin filament polymerization
GO:1903676--P:positive regulation of cap-dependent translational initiation
GO:1903679--P:positive regulation of cap-independent translational initiation
GO:1902237--P:positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
GO:0010976--P:positive regulation of neuron projection development
GO:0042102--P:positive regulation of T cell proliferation
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0036493--P:positive regulation of translation in response to endoplasmic reticulum stress
GO:0030334--P:regulation of cell migration
GO:0051707--P:response to other organism
GO:0006930--P:substrate-dependent cell migration, cell extension
GO:0042110--P:T cell activation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002115	Ailuropoda melanoleuca	99.04	2.00e-175	608.00
IUUC-Bta-013039	Bos taurus	99.04	2.00e-175	608.00
IUUC-Cja-019546	Callithrix jacchus	98.40	3.00e-173	600.00
IUUC-Cfa-020462	Canis familiaris	99.36	4.00e-176	610.00
IUUC-Cpo-022009	Cavia porcellus	98.40	2.00e-174	605.00
IUUC-Csa-023875	Chlorocebus sabaeus	100.00	3.00e-176	610.00
IUUC-Cho-024368	Choloepus hoffmanni	97.14	2.00e-149	521.00
IUUC-Dno-029593	Dasypus novemcinctus	98.73	4.00e-174	603.00
IUUC-Dor-030730	Dipodomys ordii	98.40	0.00e+00	641.00
IUUC-Ete-032906	Echinops telfairi	97.76	5.00e-172	596.00
IUUC-Eca-033378	Equus caballus	98.87	8.00e-146	509.00
IUUC-Eeu-034743	Erinaceus europaeus	86.26	2.00e-156	545.00
IUUC-Fca-035745	Felis catus	99.04	0.00e+00	649.00
IUUC-Ggo-045487	Gorilla gorilla	100.00	3.00e-176	610.00
IUUC-Hsa-045902	Homo sapiens	100.00	3.00e-176	610.00
IUUC-Itr-047923	Ictidomys tridecemlineatus	99.04	1.00e-175	608.00
IUUC-Laf-053845	Loxodonta africana	98.72	6.00e-175	606.00
IUUC-Meu-056139	Macropus eugenii	95.21	6.00e-168	583.00
IUUC-Mmr-061108	Microcebus murinus	84.35	5.00e-135	473.00
IUUC-Mdo-062258	Monodelphis domestica	94.57	4.00e-168	583.00
IUUC-Mmu-063970	Mus musculus	98.72	0.00e+00	648.00
IUUC-Mpu-066093	Mustela putorius furo	98.72	5.00e-175	606.00
IUUC-Mlu-067193	Myotis lucifugus	99.04	4.00e-175	607.00
IUUC-Nle-069611	Nomascus leucogenys	100.00	3.00e-176	610.00
IUUC-Opr-070984	Ochotona princeps	97.47	1.00e-140	491.00
IUUC-Oan-072976	Ornithorhynchus anatinus	88.48	5.00e-129	453.00
IUUC-Ocu-073905	Oryctolagus cuniculus	99.36	5.00e-176	610.00
IUUC-Oga-088588	Otolemur garnettii	99.36	2.00e-175	608.00
IUUC-Oar-089973	Ovis aries	99.36	5.00e-176	610.00
IUUC-Ptr-090968	Pan troglodytes	100.00	3.00e-176	610.00
IUUC-Pab-097807	Pongo abelii	99.68	5.00e-176	610.00
IUUC-Pca-100522	Procavia capensis	98.40	3.00e-173	600.00
IUUC-Pva-103083	Pteropus vampyrus	99.36	1.00e-175	608.00
IUUC-Rno-104839	Rattus norvegicus	95.85	1.00e-176	612.00
IUUC-Sha-107294	Sarcophilus harrisii	93.93	4.00e-166	577.00
IUUC-Sar-113675	Sorex araneus	97.44	3.00e-171	594.00
IUUC-Ssc-116442	Sus scrofa	97.76	0.00e+00	641.00
IUUC-Tsy-119184	Tarsius syrichta	90.54	1.00e-143	502.00
IUUC-Ttr-129155	Tursiops truncatus	97.44	8.00e-174	602.00
IUUC-Vpa-130344	Vicugna pacos	99.04	1.00e-175	608.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence