iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000008881.3	ENSMMUT00000012419.3	ENSMMUP00000011648.3
ENSMMUG00000008881.3	ENSMMUT00000062121.1	ENSMMUP00000047497.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.90e-09	38.1	107	153

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCr 52
           ++C +C + + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr
   Q: 107  TYC-LCNQVSYGE--MIGCDNeqCPiEWFHFSCVSLT---YKPKGK-WYCPKCR 153
           69*.*******99..*****999*99***********...888886.******8 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MLELVENRAR QMELHSQCFQ DPAESERASD KAKMDSSQPE RSSRRPRRQR TSESRDLCHM 60
ANGIEDCDDQ PPKEKKSKSA KKKKRSKAKQ EREASPVEFA IDPNEPTYCL CNQVSYGEMI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCCCCTGGG CTGGTGCTGC GGGGGCGGGG AGTGAGGGCT GCTCTGGGGG GAGTGGAGAT 60
CGGGGAGCGC GGCCGTGCCC TCTCGAGCGG CTGCGGGGTC CCCGCGGCGC CGGGCTGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028639--ING2
IPR028651--ING_fam
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

SMART

SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0003682--F:chromatin binding
GO:0008270--F:zinc ion binding
GO:0006325--P:chromatin organization
GO:0008285--P:negative regulation of cell proliferation
GO:0042981--P:regulation of apoptotic process
GO:2000772--P:regulation of cellular senescence

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002213	Ailuropoda melanoleuca	97.70	4.00e-72	264.00
IUUC-Apl-003705	Anas platyrhynchos	89.08	5.00e-66	243.00
IUUC-Aca-004990	Anolis carolinensis	83.33	1.00e-59	223.00
IUUC-Ame-011426	Astyanax mexicanus	69.19	8.00e-53	200.00
IUUC-Bta-012721	Bos taurus	98.28	9.00e-73	266.00
IUUC-Cja-018960	Callithrix jacchus	98.85	2.00e-72	265.00
IUUC-Cfa-020869	Canis familiaris	97.13	1.00e-71	262.00
IUUC-Cpo-021414	Cavia porcellus	95.40	1.00e-70	259.00
IUUC-Csa-023304	Chlorocebus sabaeus	100.00	1.00e-73	269.00
IUUC-Dno-029945	Dasypus novemcinctus	97.70	2.00e-72	265.00
IUUC-Dor-030141	Dipodomys ordii	96.55	2.00e-70	258.00
IUUC-Ete-032709	Echinops telfairi	97.13	6.00e-72	263.00
IUUC-Eca-033432	Equus caballus	98.85	1.00e-72	266.00
IUUC-Eeu-035285	Erinaceus europaeus	98.28	3.00e-72	264.00
IUUC-Fca-036467	Felis catus	98.28	4.00e-72	264.00
IUUC-Fal-036700	Ficedula albicollis	88.51	2.00e-65	241.00
IUUC-Gga-040175	Gallus gallus	88.51	8.00e-66	243.00
IUUC-Hsa-045837	Homo sapiens	100.00	1.00e-73	269.00
IUUC-Itr-049062	Ictidomys tridecemlineatus	97.70	4.00e-72	264.00
IUUC-Lch-049965	Latimeria chalumnae	84.48	2.00e-61	229.00
IUUC-Laf-053353	Loxodonta africana	98.85	5.00e-73	267.00
IUUC-Meu-056470	Macropus eugenii	97.13	6.00e-71	260.00
IUUC-Mga-059570	Meleagris gallopavo	88.51	2.00e-65	241.00
IUUC-Mmr-061385	Microcebus murinus	99.43	3.00e-73	268.00
IUUC-Mdo-062144	Monodelphis domestica	97.70	2.00e-71	262.00
IUUC-Mmu-063215	Mus musculus	96.55	6.00e-72	263.00
IUUC-Mpu-065749	Mustela putorius furo	97.13	1.00e-71	262.00
IUUC-Mlu-067245	Myotis lucifugus	71.84	4.00e-64	237.00
IUUC-Nle-069968	Nomascus leucogenys	99.43	2.00e-72	265.00
IUUC-Ocu-074870	Oryctolagus cuniculus	98.85	4.00e-73	267.00
IUUC-Ola-087400	Oryzias latipes	89.02	2.00e-43	168.00
IUUC-Oga-088336	Otolemur garnettii	98.85	1.00e-72	266.00
IUUC-Oar-090136	Ovis aries	97.70	2.00e-72	265.00
IUUC-Ptr-091348	Pan troglodytes	100.00	4.00e-73	267.00
IUUC-Pan-092819	Papio anubis	100.00	1.00e-73	269.00
IUUC-Psi-093854	Pelodiscus sinensis	86.21	3.00e-61	227.00
IUUC-Pab-098346	Pongo abelii	99.43	3.00e-73	268.00
IUUC-Pca-100278	Procavia capensis	95.40	1.00e-70	259.00
IUUC-Pva-103190	Pteropus vampyrus	99.43	3.00e-73	268.00
IUUC-Rno-104940	Rattus norvegicus	95.98	9.00e-71	259.00
IUUC-Sha-107533	Sarcophilus harrisii	97.13	2.00e-72	265.00
IUUC-Sar-113630	Sorex araneus	95.98	1.00e-71	261.00
IUUC-Ssc-115734	Sus scrofa	99.43	4.00e-73	268.00
IUUC-Tgu-117034	Taeniopygia guttata	89.08	7.00e-66	243.00
IUUC-Tsy-119494	Tarsius syrichta	99.43	1.00e-72	265.00
IUUC-Ttr-128442	Tursiops truncatus	98.85	1.00e-72	265.00
IUUC-Vpa-130063	Vicugna pacos	97.70	4.00e-72	264.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence