iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssc-115734

Ensembl Protein ID

ENSSSCP00000028185.1

UniProt Accession

I3LVN3; I3LVN3_PIG

Genbank Protein ID

ENSSSCP00000028185

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

FP340196

Gene Name

ING2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000024555.1	ENSSSCT00000025252.1	ENSSSCP00000028185.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	4.40e-09	36.7	227	273

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCr 52
           ++C +C + + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr
   Q: 227  TYC-LCNQVSYGE--MIGCDNeqCPiEWFHFSCVSLT---YKPKGK-WYCPKCR 273
           69*.*******99..*****999*99***********...888886.******8 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

AAAAAAARSS SGGRMLGQQQ QQLYSSAALL TGERSRLLTC YVQDYLECVE SLPHDMQRNV 60
SVLRELDNKY QETLKEIDDV YEKYKKEDDS NQKKRLQQHL QRALINSQEL GDEKIQIVTQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGGCGGCGG CGGCGGCGGC GAGGAGCAGC AGCGGCGGCA GGATGTTAGG GCAGCAGCAG 60
CAGCAACTCT ACTCGTCGGC CGCACTCCTG ACCGGGGAGC GGAGCCGGCT TCTCACCTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028639--ING2
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0016602--C:CCAAT-binding factor complex
GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0005886--C:plasma membrane
GO:0016580--C:Sin3 complex
GO:0003682--F:chromatin binding
GO:0003677--F:DNA binding
GO:0035091--F:phosphatidylinositol binding
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0030317--P:flagellated sperm motility
GO:0048133--P:male germ-line stem cell asymmetric division
GO:0007141--P:male meiosis I
GO:2001234--P:negative regulation of apoptotic signaling pathway
GO:0008285--P:negative regulation of cell proliferation
GO:0031065--P:positive regulation of histone deacetylation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0030511--P:positive regulation of transforming growth factor beta receptor signaling pathway
GO:2000772--P:regulation of cellular senescence
GO:0072520--P:seminiferous tubule development
GO:0007286--P:spermatid development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002213	Ailuropoda melanoleuca	98.93	1.00e-122	432.00
IUUC-Apl-003705	Anas platyrhynchos	88.79	4.00e-92	330.00
IUUC-Aca-004990	Anolis carolinensis	81.08	2.00e-98	351.00
IUUC-Ame-011426	Astyanax mexicanus	70.80	1.00e-84	305.00
IUUC-Bta-012721	Bos taurus	98.23	5.00e-122	429.00
IUUC-Cja-018960	Callithrix jacchus	98.86	1.00e-107	382.00
IUUC-Cfa-020869	Canis familiaris	98.58	1.00e-123	435.00
IUUC-Cpo-021414	Cavia porcellus	97.14	1.00e-120	425.00
IUUC-Csa-023304	Chlorocebus sabaeus	98.93	3.00e-114	404.00
IUUC-Cho-024577	Choloepus hoffmanni	59.21	4.00e-57	214.00
IUUC-Cne-027005	Cryptococcus neoformans	46.97	2.00e-15	76.30
IUUC-Dre-028562	Danio rerio	68.63	3.00e-89	321.00
IUUC-Dno-029945	Dasypus novemcinctus	98.86	5.00e-117	413.00
IUUC-Dor-030141	Dipodomys ordii	97.50	1.00e-119	422.00
IUUC-Ete-032709	Echinops telfairi	96.11	4.00e-129	453.00
IUUC-Eca-033432	Equus caballus	99.63	1.00e-121	428.00
IUUC-Eeu-035285	Erinaceus europaeus	99.02	6.00e-92	329.00
IUUC-Fca-036467	Felis catus	99.24	6.00e-117	412.00
IUUC-Fal-036700	Ficedula albicollis	87.56	3.00e-91	327.00
IUUC-Fox-037925	Fusarium oxysporum	67.39	4.00e-19	88.60
IUUC-Gmo-038748	Gadus morhua	63.04	2.00e-85	308.00
IUUC-Gga-040175	Gallus gallus	88.34	7.00e-92	329.00
IUUC-Gac-041403	Gasterosteus aculeatus	64.23	3.00e-90	324.00
IUUC-Ggo-045481	Gorilla gorilla	57.33	2.00e-57	216.00
IUUC-Hsa-045837	Homo sapiens	98.93	3.00e-114	404.00
IUUC-Itr-049062	Ictidomys tridecemlineatus	98.93	8.00e-123	432.00
IUUC-Lch-049965	Latimeria chalumnae	80.92	8.00e-101	359.00
IUUC-Loc-052038	Lepisosteus oculatus	59.06	1.00e-67	249.00
IUUC-Laf-053353	Loxodonta africana	97.33	1.00e-101	362.00
IUUC-Mcc-055155	Macaca mulatta	99.43	4.00e-74	269.00
IUUC-Meu-056470	Macropus eugenii	93.70	4.00e-112	397.00
IUUC-Mga-059570	Meleagris gallopavo	88.34	3.00e-91	327.00
IUUC-Mmr-061385	Microcebus murinus	99.29	9.00e-115	405.00
IUUC-Mdo-062144	Monodelphis domestica	93.75	1.00e-113	402.00
IUUC-Mmu-063215	Mus musculus	97.51	8.00e-121	426.00
IUUC-Mpu-065749	Mustela putorius furo	98.33	1.00e-100	358.00
IUUC-Mlu-067586	Myotis lucifugus	56.32	1.00e-68	252.00
IUUC-Nle-069968	Nomascus leucogenys	98.95	7.00e-83	299.00
IUUC-Opr-070835	Ochotona princeps	77.63	3.00e-37	147.00
IUUC-Ont-071524	Oreochromis niloticus	65.93	4.00e-87	314.00
IUUC-Oan-073023	Ornithorhynchus anatinus	57.51	5.00e-72	263.00
IUUC-Ocu-074870	Oryctolagus cuniculus	98.59	3.00e-122	430.00
IUUC-Ola-087400	Oryzias latipes	89.02	1.00e-44	172.00
IUUC-Oga-088336	Otolemur garnettii	97.91	3.00e-115	407.00
IUUC-Oar-090136	Ovis aries	98.89	3.00e-120	424.00
IUUC-Ptr-091348	Pan troglodytes	99.47	1.00e-83	301.00
IUUC-Pan-092819	Papio anubis	98.93	3.00e-114	404.00
IUUC-Psi-093266	Pelodiscus sinensis	61.11	1.00e-74	272.00
IUUC-Pma-094265	Petromyzon marinus	70.83	2.00e-31	127.00
IUUC-Pfo-096633	Poecilia formosa	63.79	5.00e-81	293.00
IUUC-Pab-098346	Pongo abelii	98.57	8.00e-114	402.00
IUUC-Pca-100278	Procavia capensis	96.06	9.00e-118	415.00
IUUC-Pva-103190	Pteropus vampyrus	100.00	4.00e-118	417.00
IUUC-Rno-104940	Rattus norvegicus	97.73	1.00e-115	408.00
IUUC-Sha-107533	Sarcophilus harrisii	91.91	2.00e-114	404.00
IUUC-Sar-113630	Sorex araneus	97.07	4.00e-91	326.00
IUUC-Tgu-117034	Taeniopygia guttata	88.00	8.00e-92	328.00
IUUC-Tru-118168	Takifugu rubripes	60.34	1.00e-81	295.00
IUUC-Tsy-119494	Tarsius syrichta	100.00	5.00e-84	303.00
IUUC-Tni-120100	Tetraodon nigroviridis	60.52	1.00e-77	282.00
IUUC-Ttr-128442	Tursiops truncatus	99.51	2.00e-92	331.00
IUUC-Vpa-130063	Vicugna pacos	98.57	2.00e-122	431.00
IUUC-Xtr-132348	Xenopus tropicalis	70.21	5.00e-70	257.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence