iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003800

Ensembl Protein ID

ENSAPLP00000012492.1

UniProt Accession

U3IZ16; U3IZ16_ANAPL

Genbank Protein ID

ENSAPLP00000012492

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01102898

Gene Name

MDM4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000012694.1	ENSAPLT00000013233.1	ENSAPLP00000012492.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	60.32	9.00e-153	537.00	IUUC-Hsa-046950

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

MTSSSSAQHP AAEDACRITL GQANQVRPKL PLLKILQAAG AQGETFTLKE VMHHLGQYIM 60
VKQLYDKRQQ HMVYCGGDQL GELLGLESFS VKDPSPVYEM LKRNLTSAAM TDAAQNLAKE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACATCTT CAAGCTCTGC CCAGCATCCA GCAGCTGAGG ATGCCTGCAG AATCACTCTT 60
GGACAAGCTA ACCAGGTAAT TATCTCCCCT ACTTACCTTC ATTGCTTTCC TCTCACTAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome

Interpro

IPR015458--MDM4
IPR016495--p53_neg-reg_MDM_2/4
IPR003121--SWIB_MDM2_domain
IPR001876--Znf_RanBP2
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2

Pfam

PF02201--SWIB

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0008283--P:cell proliferation
GO:0071456--P:cellular response to hypoxia
GO:0030330--P:DNA damage response, signal transduction by p53 class mediator
GO:0045023--P:G0 to G1 transition
GO:0043066--P:negative regulation of apoptotic process
GO:0071157--P:negative regulation of cell cycle arrest
GO:0042177--P:negative regulation of protein catabolic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0006461--P:protein complex assembly
GO:0050821--P:protein stabilization

KEGG

apla:101795668

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001467	Ailuropoda melanoleuca	59.03	7.00e-156	543.00
IUUC-Aca-004608	Anolis carolinensis	61.90	5.00e-155	540.00
IUUC-Ame-010869	Astyanax mexicanus	46.20	9.00e-112	396.00
IUUC-Bta-013287	Bos taurus	60.16	4.00e-167	580.00
IUUC-Cja-019305	Callithrix jacchus	59.92	4.00e-150	524.00
IUUC-Cfa-020393	Canis familiaris	60.81	7.00e-161	559.00
IUUC-Cpo-022166	Cavia porcellus	57.94	4.00e-150	523.00
IUUC-Csa-023654	Chlorocebus sabaeus	59.43	3.00e-158	551.00
IUUC-Cho-024403	Choloepus hoffmanni	55.19	1.00e-77	283.00
IUUC-Csv-026151	Ciona savignyi	23.86	5.00e-11	60.80
IUUC-Dre-027754	Danio rerio	49.11	3.00e-121	428.00
IUUC-Dno-029630	Dasypus novemcinctus	61.34	5.00e-164	570.00
IUUC-Dor-031064	Dipodomys ordii	59.69	8.00e-108	383.00
IUUC-Ete-032901	Echinops telfairi	55.49	6.00e-151	526.00
IUUC-Eca-034234	Equus caballus	62.60	4.00e-176	610.00
IUUC-Eeu-035015	Erinaceus europaeus	55.61	4.00e-58	218.00
IUUC-Fca-036587	Felis catus	60.32	5.00e-162	563.00
IUUC-Fal-036906	Ficedula albicollis	74.38	0.00e+00	686.00
IUUC-Gmo-038646	Gadus morhua	43.87	5.00e-105	374.00
IUUC-Gga-040124	Gallus gallus	92.40	0.00e+00	632.00
IUUC-Gac-042397	Gasterosteus aculeatus	46.37	5.00e-114	404.00
IUUC-Ggo-045505	Gorilla gorilla	58.82	2.00e-159	555.00
IUUC-Hsa-046950	Homo sapiens	59.03	3.00e-160	558.00
IUUC-Itr-048886	Ictidomys tridecemlineatus	56.82	7.00e-159	553.00
IUUC-Lch-050141	Latimeria chalumnae	52.62	8.00e-130	456.00
IUUC-Loc-051921	Lepisosteus oculatus	49.60	2.00e-119	422.00
IUUC-Laf-054281	Loxodonta africana	58.13	4.00e-156	544.00
IUUC-Mcc-055462	Macaca mulatta	55.47	4.00e-143	501.00
IUUC-Meu-056294	Macropus eugenii	65.59	2.00e-126	445.00
IUUC-Mga-059924	Meleagris gallopavo	89.07	0.00e+00	855.00
IUUC-Mmr-061428	Microcebus murinus	61.13	1.00e-170	592.00
IUUC-Mdo-062643	Monodelphis domestica	62.78	5.00e-171	593.00
IUUC-Mmu-063229	Mus musculus	60.57	2.00e-154	538.00
IUUC-Mpu-065782	Mustela putorius furo	58.82	1.00e-158	552.00
IUUC-Mlu-068105	Myotis lucifugus	56.24	6.00e-151	526.00
IUUC-Nle-069549	Nomascus leucogenys	59.03	1.00e-160	558.00
IUUC-Opr-070568	Ochotona princeps	58.97	1.00e-150	525.00
IUUC-Ont-072276	Oreochromis niloticus	47.88	2.00e-123	435.00
IUUC-Oan-072787	Ornithorhynchus anatinus	65.52	8.00e-163	566.00
IUUC-Ocu-074912	Oryctolagus cuniculus	59.31	4.00e-160	557.00
IUUC-Ola-087037	Oryzias latipes	46.81	7.00e-107	380.00
IUUC-Oga-088953	Otolemur garnettii	59.07	7.00e-151	526.00
IUUC-Oar-089202	Ovis aries	60.16	2.00e-169	588.00
IUUC-Ptr-090964	Pan troglodytes	59.23	4.00e-161	560.00
IUUC-Pan-091975	Papio anubis	60.93	4.00e-160	557.00
IUUC-Psi-093558	Pelodiscus sinensis	78.03	0.00e+00	672.00
IUUC-Pfo-096454	Poecilia formosa	49.28	3.00e-121	428.00
IUUC-Pab-098123	Pongo abelii	59.03	6.00e-161	560.00
IUUC-Pca-101112	Procavia capensis	54.81	2.00e-146	511.00
IUUC-Pva-103098	Pteropus vampyrus	56.56	2.00e-148	518.00
IUUC-Rno-105930	Rattus norvegicus	61.26	3.00e-154	537.00
IUUC-Sha-107512	Sarcophilus harrisii	63.54	3.00e-158	551.00
IUUC-Sar-113584	Sorex araneus	54.93	5.00e-141	493.00
IUUC-Tgu-116766	Taeniopygia guttata	75.16	1.00e-137	482.00
IUUC-Tru-117829	Takifugu rubripes	48.88	6.00e-117	414.00
IUUC-Tsy-119268	Tarsius syrichta	57.65	1.00e-65	243.00
IUUC-Tni-120204	Tetraodon nigroviridis	48.57	2.00e-112	399.00
IUUC-Tbe-127840	Tupaia belangeri	54.49	6.00e-82	297.00
IUUC-Ttr-128863	Tursiops truncatus	59.15	2.00e-160	558.00
IUUC-Vpa-130718	Vicugna pacos	60.09	2.00e-157	548.00
IUUC-Xtr-132320	Xenopus tropicalis	47.69	6.00e-100	357.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence