iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073320

UUCD1 version

UUC-OrA-00137

Ensembl Protein ID

ENSOANP00000015376.2

UniProt Accession

F6SUG2; F6SUG2_ORNAN

Protein Name

Uncharacterized protein

Gene Name

KLHL25

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000009685.3	ENSOANT00000015379.3	ENSOANP00000015376.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.00e-19	70.0	46	114
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	2.70e-09	36.2	146	177

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikd.vqpevfrallkFlYtgkldene 69
           +Dv+l  g++ f++h++vLaasS++F+a+f+++l+es   + v+++d + pev++ ll+F Y++++ +ne
   Q: 46   TDVTLRAGDRAFPCHRAVLAASSRYFEAMFSHGLRESL-DEAVNFHDsLHPEVLEPLLDFAYSSRIIINE 114
           7************************************9.*******99*****************99987 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           + Nclg++ ++d+++c++L++   +++l hF+
   Q: 146  PTNCLGMMLLSDAHQCRRLYELSWRMCLAHFE 177
           78*****************************5 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MSVSVHENRK SRSSTGSANI SVFHKPSHPD CVLAHLNTLR KHRMFTDVTL RAGDRAFPCH 60
RAVLAASSRY FEAMFSHGLR ESLDEAVNFH DSLHPEVLEP LLDFAYSSRI IINEENAESL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCGTCA GCGTCCATGA AAACCGCAAG TCCCGCAGCA GCACGGGCTC CGCGAACATC 60
TCGGTCTTCC ACAAGCCCTC CCACCCGGAC TGTGTCCTGG CCCACCTGAA CACCCTGCGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030565--KLHL25
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0006446--P:regulation of translational initiation

KEGG

oaa:100075321

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002373	Ailuropoda melanoleuca	86.25	0.00e+00	1079.00
IUUC-Apl-003543	Anas platyrhynchos	84.75	0.00e+00	1026.00
IUUC-Aca-004729	Anolis carolinensis	81.83	0.00e+00	1007.00
IUUC-Ame-011020	Astyanax mexicanus	82.00	0.00e+00	990.00
IUUC-Bta-012955	Bos taurus	86.59	0.00e+00	1080.00
IUUC-Cja-018839	Callithrix jacchus	85.57	0.00e+00	1070.00
IUUC-Cfa-020224	Canis familiaris	86.25	0.00e+00	1082.00
IUUC-Cpo-021593	Cavia porcellus	84.55	0.00e+00	1015.00
IUUC-Csa-023276	Chlorocebus sabaeus	86.25	0.00e+00	1076.00
IUUC-Dre-028053	Danio rerio	82.34	0.00e+00	965.00
IUUC-Dno-029287	Dasypus novemcinctus	87.27	0.00e+00	1083.00
IUUC-Dor-030908	Dipodomys ordii	79.46	0.00e+00	978.00
IUUC-Dse-031490	Dothistroma septosporum	27.74	8.00e-05	40.00
IUUC-Fca-035897	Felis catus	86.25	0.00e+00	1078.00
IUUC-Fal-037036	Ficedula albicollis	84.72	0.00e+00	1028.00
IUUC-Gmo-039345	Gadus morhua	82.17	0.00e+00	967.00
IUUC-Gga-040404	Gallus gallus	84.89	0.00e+00	1033.00
IUUC-Gac-042447	Gasterosteus aculeatus	81.83	0.00e+00	979.00
IUUC-Ggo-045060	Gorilla gorilla	86.08	0.00e+00	1074.00
IUUC-Hsa-046494	Homo sapiens	86.08	0.00e+00	1074.00
IUUC-Itr-047993	Ictidomys tridecemlineatus	85.91	0.00e+00	1077.00
IUUC-Lch-050211	Latimeria chalumnae	81.80	0.00e+00	996.00
IUUC-Loc-052578	Lepisosteus oculatus	82.85	0.00e+00	1003.00
IUUC-Laf-053498	Loxodonta africana	86.25	0.00e+00	1029.00
IUUC-Mcc-055033	Macaca mulatta	86.42	0.00e+00	1077.00
IUUC-Meu-056893	Macropus eugenii	86.76	0.00e+00	1083.00
IUUC-Mor-057181	Magnaporthe oryzae	24.54	5.00e-10	57.80
IUUC-Mga-060025	Meleagris gallopavo	84.89	0.00e+00	1031.00
IUUC-Mmr-060658	Microcebus murinus	86.08	0.00e+00	1073.00
IUUC-Mdo-062667	Monodelphis domestica	86.93	0.00e+00	1088.00
IUUC-Mmu-063125	Mus musculus	83.87	0.00e+00	1025.00
IUUC-Mpu-066209	Mustela putorius furo	86.25	0.00e+00	1079.00
IUUC-Mlu-068237	Myotis lucifugus	84.72	0.00e+00	1025.00
IUUC-Nle-069454	Nomascus leucogenys	85.93	0.00e+00	1061.00
IUUC-Ont-072138	Oreochromis niloticus	81.83	0.00e+00	967.00
IUUC-Ocu-073765	Oryctolagus cuniculus	83.53	0.00e+00	1014.00
IUUC-Oga-088002	Otolemur garnettii	86.93	0.00e+00	1083.00
IUUC-Oar-089481	Ovis aries	86.42	0.00e+00	1080.00
IUUC-Ptr-091200	Pan troglodytes	85.91	0.00e+00	1071.00
IUUC-Psi-093884	Pelodiscus sinensis	84.21	0.00e+00	1024.00
IUUC-Pno-095143	Phaeosphaeria nodorum	26.42	7.00e-15	73.90
IUUC-Pva-102321	Pteropus vampyrus	85.91	0.00e+00	1071.00
IUUC-Rno-104835	Rattus norvegicus	83.53	0.00e+00	1023.00
IUUC-Sha-107528	Sarcophilus harrisii	86.25	0.00e+00	1079.00
IUUC-Ssc-116161	Sus scrofa	86.59	0.00e+00	1081.00
IUUC-Tgu-116569	Taeniopygia guttata	84.55	0.00e+00	1025.00
IUUC-Tni-120525	Tetraodon nigroviridis	75.47	0.00e+00	867.00
IUUC-Ttr-129297	Tursiops truncatus	86.93	0.00e+00	1085.00
IUUC-Vda-129835	Verticillium dahliae	35.59	3.00e-06	46.20

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence