iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Csa-023911

Ensembl Protein ID

ENSCSAP00000003543.1

UniProt Accession

A0A0D9R4K4; A0A0D9R4K4_CHLSB

Genbank Protein ID

ENSCSAP00000003543

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AQIB01110882

Gene Name

HCLS1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAG00000007278.1	ENSCSAT00000005321.1	ENSCSAP00000003543.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.80e-12	46.4	445	496

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
            +lydy+++ +deL++   dv++ i  e  degW++g    +g  GlfP+n+v+ l
   Q: 445  VALYDYQGEGSDELSFDPDDVITDI--EMVDEGWWRG--RCHGHFGLFPANYVKLL 496
           58**********************9..9*********..8*************977 PP

Organism

Chlorocebus sabaeus

Protein Sequence
(Fasta)

MLLFLLHSPE GRLEHWGCSS RMWKSVVGHD VSVSVETQGD DWDTDPDFVN DISEKEQRWG 60
AKTIEGSGRT EHINIHQLRN KVSEEHDVLK KKEMESGPKA SHGYGGRFGV ERDRMDKSAV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCAGGAAAT GACGAAAACC TGAATACGGA ACTGAAGCAG CAGCTCAGTT TCTCACTCCG 60
AAGTGGCAGC AGCCAGAGAG GGAGTCGGTG TGGACGCGAG GAGCCGGGCG CTTAGAACAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR028534--HS1
IPR003134--Hs1_Cortactin
IPR001452--SH3_domain

PROSITE

PS51090--CORTACTIN
PS50002--SH3

Pfam

PF02218--HS1_rep
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0005667--C:transcription factor complex
GO:0030041--P:actin filament polymerization
GO:0071345--P:cellular response to cytokine stimulus
GO:0030218--P:erythrocyte differentiation
GO:2000107--P:negative regulation of leukocyte apoptotic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0008284--P:positive regulation of cell proliferation
GO:0030854--P:positive regulation of granulocyte differentiation
GO:0045651--P:positive regulation of macrophage differentiation
GO:0033138--P:positive regulation of peptidyl-serine phosphorylation
GO:0014068--P:positive regulation of phosphatidylinositol 3-kinase signaling
GO:0051897--P:positive regulation of protein kinase B signaling
GO:0042993--P:positive regulation of transcription factor import into nucleus
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0042531--P:positive regulation of tyrosine phosphorylation of STAT protein
GO:0030833--P:regulation of actin filament polymerization
GO:0009725--P:response to hormone

KEGG

csab:103228199

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001194	Ailuropoda melanoleuca	85.30	0.00e+00	729.00
IUUC-Bta-012591	Bos taurus	84.77	0.00e+00	674.00
IUUC-Cja-019982	Callithrix jacchus	92.50	0.00e+00	741.00
IUUC-Cfa-020262	Canis familiaris	83.06	0.00e+00	661.00
IUUC-Cpo-021362	Cavia porcellus	86.55	0.00e+00	655.00
IUUC-Dor-030437	Dipodomys ordii	77.15	1.00e-172	599.00
IUUC-Ete-033160	Echinops telfairi	75.33	1.00e-154	539.00
IUUC-Eca-033269	Equus caballus	82.72	0.00e+00	714.00
IUUC-Eeu-035032	Erinaceus europaeus	72.44	2.00e-122	432.00
IUUC-Fca-035999	Felis catus	80.80	0.00e+00	751.00
IUUC-Fal-037107	Ficedula albicollis	50.47	8.00e-122	430.00
IUUC-Gga-040335	Gallus gallus	51.40	1.00e-130	459.00
IUUC-Ggo-044505	Gorilla gorilla	90.08	0.00e+00	741.00
IUUC-Hsa-046728	Homo sapiens	97.46	0.00e+00	638.00
IUUC-Itr-048592	Ictidomys tridecemlineatus	68.31	2.00e-169	588.00
IUUC-Laf-054202	Loxodonta africana	82.41	0.00e+00	674.00
IUUC-Mcc-055824	Macaca mulatta	94.33	0.00e+00	773.00
IUUC-Mmr-061281	Microcebus murinus	77.23	3.00e-173	601.00
IUUC-Mdo-062515	Monodelphis domestica	69.37	4.00e-154	537.00
IUUC-Mmu-064341	Mus musculus	81.67	0.00e+00	682.00
IUUC-Mpu-066565	Mustela putorius furo	87.18	0.00e+00	699.00
IUUC-Mlu-066942	Myotis lucifugus	81.55	0.00e+00	684.00
IUUC-Nle-069436	Nomascus leucogenys	95.46	0.00e+00	772.00
IUUC-Opr-070288	Ochotona princeps	79.92	9.00e-171	592.00
IUUC-Ocu-074686	Oryctolagus cuniculus	84.63	0.00e+00	634.00
IUUC-Ola-086894	Oryzias latipes	59.79	5.00e-95	341.00
IUUC-Oga-088585	Otolemur garnettii	78.64	0.00e+00	669.00
IUUC-Oar-089686	Ovis aries	85.63	0.00e+00	709.00
IUUC-Ptr-090461	Pan troglodytes	98.31	0.00e+00	644.00
IUUC-Pan-091887	Papio anubis	98.95	0.00e+00	766.00
IUUC-Psi-093785	Pelodiscus sinensis	53.48	4.00e-143	501.00
IUUC-Pab-098222	Pongo abelii	95.48	0.00e+00	767.00
IUUC-Pca-100668	Procavia capensis	82.08	0.00e+00	680.00
IUUC-Pva-102767	Pteropus vampyrus	72.61	1.00e-168	586.00
IUUC-Rno-106001	Rattus norvegicus	83.72	0.00e+00	686.00
IUUC-Sar-113338	Sorex araneus	75.98	6.00e-172	597.00
IUUC-Ssc-116027	Sus scrofa	83.81	0.00e+00	724.00
IUUC-Tgu-117472	Taeniopygia guttata	59.18	3.00e-154	538.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence