iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssc-115362

Ensembl Protein ID

ENSSSCP00000012120.2

UniProt Accession

F1SKJ0; F1SKJ0_PIG

Genbank Protein ID

ENSSSCP00000012120

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

CU466318

Gene Name

ARIH2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000011367.2	ENSSSCT00000012445.2	ENSSSCP00000012120.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	1.30e-55	188.9	137	324

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpekleeseikellveeelykryekllleevveadaalkw 90
           C+vC+ ++  +e++ +l+C+h+fC++C++q++++ +k+g  + +sc+a++cp +++e+ +  ll++eel ++y+++l++++ve++++l++
   Q: 137  CAVCM-QFVRKENLLSLACQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFVFPLLPNEELRDKYRRYLFRDYVESHYQLQL 225
           9***9.77777888899************************************************************************* PP
   S: 91   cpapdCslvvllekeaeklevecekcgkefCveCkeewHeglsCkelkeklakteeekeeaeskelleanskkCpkCkvyieknegCnhm 180
           cp +dC +v+++++  ++ +v+c++c+++fC++C++++H++++C +++++l+k++   +++e++++++a++k+CpkC+++iekn+gCnhm
   Q: 226  CPGADCPMVIRVQEP-RARRVQCNRCNEVFCFKCRQMYHAPTDCATIRKWLTKCA---DDSETANYISAHTKDCPKCNICIEKNGGCNHM 311
           **************7.99*************************************...99****************************** PP
   S: 181  tCakCkaefCwlC 193
           +C+kCk++fCw+C
   Q: 312  QCSKCKHDFCWMC 324
           ************* PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MSVDMNSQGS DSNEEDYDPN CEEEEEDEDP GDIEDYYVGV ASDVEQQGAD AFDPEEYQFT 60
CLTYKESEGA LNEHMTSLAS VLKVSHSVAK LILVNFHWQV AEILDRYKSN SAQLLVEARV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCTGTGG ACATGAATAG CCAGGGGTCT GACAGCAATG AAGAGGACTA TGACCCAAAT 60
TGTGAAGAAG AGGAAGAGGA CGAAGACCCT GGGGACATAG AGGACTATTA CGTGGGAGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF01485--IBR

SMART

SM00647--IBR
SM00184--RING

Gene Ontology

GO:0031466--C:Cul5-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0005654--C:nucleoplasm
GO:0000151--C:ubiquitin ligase complex
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0048588--P:developmental cell growth
GO:0071425--P:hematopoietic stem cell proliferation
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:1903955--P:positive regulation of protein targeting to mitochondrion
GO:0070936--P:protein K48-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

ssc:100524765

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001557	Ailuropoda melanoleuca	99.19	0.00e+00	942.00
IUUC-Atr-002495	Amborella trichopoda	30.65	9.00e-51	194.00
IUUC-Apl-003878	Anas platyrhynchos	93.69	0.00e+00	879.00
IUUC-Aca-004865	Anolis carolinensis	92.87	0.00e+00	883.00
IUUC-Ago-007926	Ashbya gossypii	26.35	5.00e-44	172.00
IUUC-Bta-012901	Bos taurus	98.98	0.00e+00	937.00
IUUC-Bdi-015065	Brachypodium distachyon	28.37	1.00e-55	210.00
IUUC-Cel-018334	Caenorhabditis elegans	48.64	1.00e-126	446.00
IUUC-Cja-019728	Callithrix jacchus	97.15	0.00e+00	936.00
IUUC-Cfa-020953	Canis familiaris	99.39	0.00e+00	942.00
IUUC-Cpo-021445	Cavia porcellus	96.95	0.00e+00	935.00
IUUC-Csa-023769	Chlorocebus sabaeus	97.16	0.00e+00	935.00
IUUC-Cho-024650	Choloepus hoffmanni	86.00	0.00e+00	788.00
IUUC-Cin-025577	Ciona intestinalis	54.42	2.00e-143	502.00
IUUC-Csv-025849	Ciona savignyi	55.70	7.00e-120	423.00
IUUC-Dre-028490	Danio rerio	80.16	0.00e+00	780.00
IUUC-Dno-029942	Dasypus novemcinctus	96.35	0.00e+00	927.00
IUUC-Dor-030134	Dipodomys ordii	85.30	1.00e-151	528.00
IUUC-Dme-031853	Drosophila melanogaster	55.27	2.00e-150	525.00
IUUC-Ete-032355	Echinops telfairi	89.07	0.00e+00	835.00
IUUC-Eca-033440	Equus caballus	99.39	0.00e+00	942.00
IUUC-Eeu-035230	Erinaceus europaeus	89.36	2.00e-115	408.00
IUUC-Fca-036308	Felis catus	92.68	0.00e+00	868.00
IUUC-Fal-036974	Ficedula albicollis	93.69	0.00e+00	879.00
IUUC-Gmo-038642	Gadus morhua	81.51	0.00e+00	778.00
IUUC-Gga-041019	Gallus gallus	93.69	0.00e+00	879.00
IUUC-Gac-042014	Gasterosteus aculeatus	80.08	0.00e+00	801.00
IUUC-Ggo-045329	Gorilla gorilla	97.57	0.00e+00	937.00
IUUC-Hsa-046712	Homo sapiens	97.36	0.00e+00	937.00
IUUC-Itr-048370	Ictidomys tridecemlineatus	98.80	0.00e+00	842.00
IUUC-Kpa-049350	Komagataella pastoris	28.20	3.00e-52	199.00
IUUC-Lch-049584	Latimeria chalumnae	85.57	0.00e+00	816.00
IUUC-Loc-051826	Lepisosteus oculatus	79.62	9.00e-165	572.00
IUUC-Laf-054567	Loxodonta africana	97.15	0.00e+00	915.00
IUUC-Mcc-054919	Macaca mulatta	97.16	0.00e+00	935.00
IUUC-Meu-056332	Macropus eugenii	89.05	0.00e+00	846.00
IUUC-Mga-060132	Meleagris gallopavo	93.71	0.00e+00	883.00
IUUC-Mmr-061599	Microcebus murinus	93.12	0.00e+00	880.00
IUUC-Mdo-062186	Monodelphis domestica	94.69	0.00e+00	800.00
IUUC-Mmu-064271	Mus musculus	96.34	0.00e+00	930.00
IUUC-Mpu-066827	Mustela putorius furo	96.90	0.00e+00	828.00
IUUC-Mlu-067528	Myotis lucifugus	98.17	0.00e+00	897.00
IUUC-Nle-068995	Nomascus leucogenys	97.57	0.00e+00	937.00
IUUC-Opr-070518	Ochotona princeps	96.96	0.00e+00	897.00
IUUC-Ont-071650	Oreochromis niloticus	83.27	0.00e+00	820.00
IUUC-Oan-073676	Ornithorhynchus anatinus	94.12	0.00e+00	755.00
IUUC-Ocu-073761	Oryctolagus cuniculus	97.57	0.00e+00	937.00
IUUC-Obr-076705	Oryza brachyantha	29.59	1.00e-57	217.00
IUUC-Olo-080774	Oryza longistaminata	30.42	1.00e-49	191.00
IUUC-Ola-087204	Oryzias latipes	79.37	0.00e+00	792.00
IUUC-Olu-087826	Ostreococcus lucimarinus	30.85	5.00e-45	175.00
IUUC-Oga-088098	Otolemur garnettii	96.75	0.00e+00	929.00
IUUC-Oar-089205	Ovis aries	98.98	0.00e+00	937.00
IUUC-Ptr-091514	Pan troglodytes	97.57	0.00e+00	937.00
IUUC-Pan-092493	Papio anubis	92.45	0.00e+00	890.00
IUUC-Psi-093024	Pelodiscus sinensis	88.19	1.00e-118	418.00
IUUC-Pfo-097256	Poecilia formosa	81.84	0.00e+00	808.00
IUUC-Pab-098504	Pongo abelii	89.86	0.00e+00	837.00
IUUC-Pop-099547	Populus trichocarpa	30.85	1.00e-55	210.00
IUUC-Pca-100700	Procavia capensis	89.45	0.00e+00	831.00
IUUC-Pva-103105	Pteropus vampyrus	98.37	0.00e+00	927.00
IUUC-Rno-105289	Rattus norvegicus	96.54	0.00e+00	931.00
IUUC-Sce-106154	Saccharomyces cerevisiae	27.95	2.00e-49	189.00
IUUC-Sha-107417	Sarcophilus harrisii	92.90	0.00e+00	868.00
IUUC-Sar-113042	Sorex araneus	96.58	0.00e+00	931.00
IUUC-Tgu-117469	Taeniopygia guttata	93.38	0.00e+00	831.00
IUUC-Tru-117976	Takifugu rubripes	80.59	0.00e+00	813.00
IUUC-Tsy-118876	Tarsius syrichta	83.11	1.00e-91	329.00
IUUC-Tni-119831	Tetraodon nigroviridis	80.00	0.00e+00	794.00
IUUC-Tca-121326	Theobroma cacao	29.15	4.00e-60	225.00
IUUC-Tae-123545	Triticum aestivum	29.74	3.00e-56	212.00
IUUC-Tur-126320	Triticum urartu	29.24	7.00e-43	167.00
IUUC-Tbe-127386	Tupaia belangeri	89.06	4.00e-159	554.00
IUUC-Ttr-128315	Tursiops truncatus	99.19	0.00e+00	941.00
IUUC-Vpa-130383	Vicugna pacos	91.65	0.00e+00	842.00
IUUC-Vvi-131543	Vitis vinifera	28.78	4.00e-56	212.00
IUUC-Xtr-132945	Xenopus tropicalis	88.82	0.00e+00	869.00
IUUC-Xma-134312	Xiphophorus maculatus	80.19	0.00e+00	802.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence