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Tag Content
UUCD2 ID IUUC-Mcc-055531
UUCD1 version UUC-MaM-00649
Ensembl Protein ID ENSMMUP00000035810.2
UniProt Accession F7FBK1; F7FBK1_MACMU
Genbank Protein ID ENSMMUP00000035810
Protein Name Uncharacterized protein
Genbank Nucleotide ID JSUE03043714
Gene Name HERC4
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMMUG00000010105.3 ENSMMUT00000042798.2 ENSMMUP00000035810.2
ENSMMUG00000010105.3 ENSMMUT00000006290.3 ENSMMUP00000005917.3
ENSMMUG00000010105.3 ENSMMUT00000014107.3 ENSMMUP00000013211.3
ENSMMUG00000010105.3 ENSMMUT00000014108.3 ENSMMUP00000013212.3
ENSMMUG00000010105.3 ENSMMUT00000042546.2 ENSMMUP00000035554.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/HECT 3.90e-100 336.6 757 1080
Active Site
Position(s) Description Evidence
1049 Glycyl thioester intermediate {ECO:0000256|PROSITE-ProRule:PRU00104}
Domain Profile

   E3 activity/HECT
   S: 4    dlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           d kk l+v fvgE+++d+gGv +ef+ l+++el +p++g+f+y e+++  ++ +++      e  +lF+++G+++g+a+++  ++dl
   Q: 757  DYKKPLKVIFVGEDAVDAGGVRKEFFLLIMRELLDPKYGMFRYYEDSRLIWFSDKTF-----EDSDLFHLIGVICGLAIYNFTIVDL 838
           78999***********************************************88877.....689********************** PP
   S: 91   plsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklv 177
           +++ ++yk+ll+kk sl+dl+e++p++ +s+++++++ e+diee+ ++l+f+++ e++g t+++eL+ +G+++ V+++N++e+v+++
   Q: 839  HFPLALYKKLLKKKPSLDDLKELMPDVGRSMQQLLDYPEDDIEET-FCLNFTITVENFGATEVKELVLNGADTAVNKQNRQEFVDAY 924
           ***************************************9**998.***************************************** PP
   S: 178  veyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkaf 264
           v+y++++++++ ++af++Gf++v+  ++l lF+++el+ ++ G++++d+++l+k+t+ykg+y +++p+i+ Fwev++e+  e++++f
   Q: 925  VDYIFNKSVASLFDAFHAGFHKVCGGKVLLLFQPNELQAMVIGNTNYDWKELEKNTEYKGEYWAEHPTIKIFWEVFHELPLEKKQQF 1011
           *************************************************************************************** PP
   S: 265  LqFvTgssrlPlgGfaelkprlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           L F+Tgs+r+P+ G+++lk    vi+   + ++ lP s+TCfn+L+LP+Y+ ke+l++kL+ Ai++++gF+l
   Q: 1012 LLFLTGSDRIPILGMKSLK---LVIQStGGGEEYLPVSHTCFNLLDLPKYTDKETLRSKLIQAIDHNEGFSL 1080
           *******************...7777758889**************************************86 PP
   
Organism Macaca mulatta
Protein Sequence
(Fasta)
MLCWGNASFG QLGLGGIDEE IVLEPRKSDF FINKKVRDVG CGLRHTVFVL DDGTVYTCGC 60
NDLGQLGHEK SRKKPEQVVA LDAQNIVAVS CGEAHTLALN DKGQVYAWGL DSDGQLGLLG 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mcc-055531|E3,HECT|Macaca mulatta
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGCCCCTCCC CCGCCTCCCT CGCGTGGCCA CCTCCCCCTC TGCCTTCTCC TACCCAGTCT 60
CTTCCCCAAC TCTCCCCACC CCTAGTGCTC TCCGCCCCGC TTGCCTCCTG TTCTTCCCCG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mcc-055531|E3,HECT|Macaca mulatta
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
Interpro

IPR000569--HECT_dom
IPR009091--RCC1/BLIP-II
IPR000408--Reg_chr_condens
PROSITE

PS50237--HECT
PS00626--RCC1_2
PS50012--RCC1_3
Pfam

PF00632--HECT
PF00415--RCC1
PRINTS

PR00633--RCCNDNSATION
SMART

SM00119--HECTc
Gene Ontology

GO:0005829--C:cytosol
GO:0001650--C:fibrillar center
GO:0004842--F:ubiquitin-protein transferase activity
GO:0007283--P:spermatogenesis
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001666 Ailuropoda melanoleuca 96.02 0.00e+00 2000.00
IUUC-Apl-003295 Anas platyrhynchos 86.78 0.00e+00 1870.00
IUUC-Aca-004336 Anolis carolinensis 84.23 0.00e+00 1810.00
IUUC-Ame-010768 Astyanax mexicanus 71.35 0.00e+00 1558.00
IUUC-Bta-013279 Bos taurus 95.84 0.00e+00 1997.00
IUUC-Cja-019023 Callithrix jacchus 96.39 0.00e+00 2006.00
IUUC-Cfa-021074 Canis familiaris 96.30 0.00e+00 2008.00
IUUC-Cpo-021461 Cavia porcellus 93.81 0.00e+00 1945.00
IUUC-Csa-024261 Chlorocebus sabaeus 97.69 0.00e+00 2030.00
IUUC-Cho-024513 Choloepus hoffmanni 76.13 0.00e+00 1475.00
IUUC-Cin-025232 Ciona intestinalis 41.70 0.00e+00 800.00
IUUC-Dre-028829 Danio rerio 73.06 0.00e+00 1547.00
IUUC-Dno-029445 Dasypus novemcinctus 94.93 0.00e+00 1624.00
IUUC-Dor-030158 Dipodomys ordii 96.92 0.00e+00 879.00
IUUC-Dme-032103 Drosophila melanogaster 44.08 0.00e+00 880.00
IUUC-Ete-033072 Echinops telfairi 84.64 0.00e+00 1709.00
IUUC-Eca-033317 Equus caballus 93.80 0.00e+00 1950.00
IUUC-Fca-035682 Felis catus 95.65 0.00e+00 1985.00
IUUC-Fal-036969 Ficedula albicollis 85.48 0.00e+00 1843.00
IUUC-Gmo-038671 Gadus morhua 72.22 0.00e+00 1557.00
IUUC-Gga-041174 Gallus gallus 86.40 0.00e+00 1867.00
IUUC-Gac-042600 Gasterosteus aculeatus 72.42 0.00e+00 1500.00
IUUC-Ggo-044589 Gorilla gorilla 96.58 0.00e+00 2045.00
IUUC-Hsa-046772 Homo sapiens 96.58 0.00e+00 2042.00
IUUC-Lch-050147 Latimeria chalumnae 78.62 0.00e+00 1422.00
IUUC-Loc-052684 Lepisosteus oculatus 79.28 0.00e+00 1697.00
IUUC-Laf-053844 Loxodonta africana 95.19 0.00e+00 1980.00
IUUC-Mga-060151 Meleagris gallopavo 85.48 0.00e+00 1553.00
IUUC-Mmr-060954 Microcebus murinus 96.11 0.00e+00 2002.00
IUUC-Mdo-062246 Monodelphis domestica 90.16 0.00e+00 1764.00
IUUC-Mmu-063369 Mus musculus 94.08 0.00e+00 1973.00
IUUC-Mpu-065936 Mustela putorius furo 95.53 0.00e+00 1844.00
IUUC-Mlu-067326 Myotis lucifugus 95.65 0.00e+00 1963.00
IUUC-Nle-069453 Nomascus leucogenys 96.21 0.00e+00 1995.00
IUUC-Ont-071720 Oreochromis niloticus 73.15 0.00e+00 1558.00
IUUC-Oan-073464 Ornithorhynchus anatinus 90.36 0.00e+00 1779.00
IUUC-Ocu-074207 Oryctolagus cuniculus 97.53 0.00e+00 1896.00
IUUC-Ola-086762 Oryzias latipes 72.22 0.00e+00 1512.00
IUUC-Oga-088435 Otolemur garnettii 96.11 0.00e+00 2003.00
IUUC-Oar-089233 Ovis aries 95.84 0.00e+00 1998.00
IUUC-Ptr-091368 Pan troglodytes 96.76 0.00e+00 2045.00
IUUC-Pan-092300 Papio anubis 97.69 0.00e+00 2030.00
IUUC-Psi-093406 Pelodiscus sinensis 88.16 0.00e+00 1890.00
IUUC-Pma-094113 Petromyzon marinus 71.53 0.00e+00 1137.00
IUUC-Ppa-095354 Physcomitrella patens 31.71 1.00e-143 504.00
IUUC-Pfo-097021 Poecilia formosa 71.60 0.00e+00 1564.00
IUUC-Pab-098327 Pongo abelii 96.95 0.00e+00 2047.00
IUUC-Pca-101075 Procavia capensis 96.04 0.00e+00 821.00
IUUC-Pva-102909 Pteropus vampyrus 84.83 0.00e+00 1687.00
IUUC-Rno-105457 Rattus norvegicus 94.82 0.00e+00 1994.00
IUUC-Sha-106632 Sarcophilus harrisii 91.67 0.00e+00 1942.00
IUUC-Sar-113679 Sorex araneus 85.44 0.00e+00 1137.00
IUUC-Tgu-116849 Taeniopygia guttata 81.68 0.00e+00 1734.00
IUUC-Tru-118206 Takifugu rubripes 71.38 0.00e+00 1462.00
IUUC-Tsy-119521 Tarsius syrichta 81.68 0.00e+00 1600.00
IUUC-Tni-120233 Tetraodon nigroviridis 70.54 0.00e+00 1447.00
IUUC-Tbe-127941 Tupaia belangeri 81.25 0.00e+00 1375.00
IUUC-Ttr-128926 Tursiops truncatus 94.62 0.00e+00 1172.00
IUUC-Vpa-130448 Vicugna pacos 95.28 0.00e+00 1985.00
IUUC-Xtr-132719 Xenopus tropicalis 69.59 0.00e+00 1380.00
Created Date 25-Jun-2017

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