iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tgu-116748

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01029583

Gene Name

KLHL22

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000010167.1	ENSTGUT00000010606.1	ENSTGUP00000010496.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	5.50e-19	68.1	26	90
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	2.00e-07	30.3	125	155

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           Dv+lvv+++ ++ah+i Laas+++F+ +f ++l+e++ +++v+i+++++ ++  +l+F+Yt++l++
   Q: 26   DVVLVVEDKPIEAHRILLAASCDYFRGMFAGGLREME-QEEVHIHGISYNAMCKILNFIYTSELEL 90
           9***********************************8.*************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhFk 32
           eN l+++r+Ad+yd+ +L ++ +++ilk+F+
   Q: 125  ENILDVYRLADHYDLKHLSEQLDSYILKNFT 155
           8*****************************7 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

TYRSAEHSQA LLSGLVSLRD SSILFDVVLV VEDKPIEAHR ILLAASCDYF RGMFAGGLRE 60
MEQEEVHIHG ISYNAMCKIL NFIYTSELEL SVNSVQETLA AACQLQIPEV IKFCCDFLMS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACGTACCGCA GCGCGGAGCA CTCGCAGGCC CTGCTCAGCG GGCTGGTGTC TCTCCGGGAC 60
AGCAGCATCC TCTTCGATGT GGTGCTGGTG GTGGAAGACA AACCCATCGA GGCTCATCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030575--KLHL22
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0005813--C:centrosome
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0072686--C:mitotic spindle
GO:0005827--C:polar microtubule
GO:0051301--P:cell division
GO:0000070--P:mitotic sister chromatid segregation
GO:0007094--P:mitotic spindle assembly checkpoint
GO:0006513--P:protein monoubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002097	Ailuropoda melanoleuca	81.75	0.00e+00	914.00
IUUC-Apl-004081	Anas platyrhynchos	97.53	0.00e+00	1081.00
IUUC-Aca-005015	Anolis carolinensis	70.53	0.00e+00	792.00
IUUC-Ame-011712	Astyanax mexicanus	61.87	0.00e+00	700.00
IUUC-Bta-012594	Bos taurus	80.99	0.00e+00	908.00
IUUC-Cja-019752	Callithrix jacchus	82.23	0.00e+00	743.00
IUUC-Cfa-020884	Canis familiaris	81.94	0.00e+00	914.00
IUUC-Cpo-021711	Cavia porcellus	82.13	0.00e+00	913.00
IUUC-Csa-023211	Chlorocebus sabaeus	82.89	0.00e+00	922.00
IUUC-Dre-028395	Danio rerio	63.50	0.00e+00	715.00
IUUC-Dno-030096	Dasypus novemcinctus	81.75	0.00e+00	913.00
IUUC-Dor-030709	Dipodomys ordii	80.00	6.00e-166	577.00
IUUC-Eca-033388	Equus caballus	81.75	0.00e+00	915.00
IUUC-Eeu-034616	Erinaceus europaeus	71.86	0.00e+00	784.00
IUUC-Fca-035815	Felis catus	82.13	0.00e+00	915.00
IUUC-Fal-037311	Ficedula albicollis	99.05	0.00e+00	1064.00
IUUC-Gmo-039571	Gadus morhua	53.79	5.00e-154	537.00
IUUC-Gga-040992	Gallus gallus	97.34	0.00e+00	1081.00
IUUC-Gac-042041	Gasterosteus aculeatus	61.17	0.00e+00	664.00
IUUC-Ggo-045141	Gorilla gorilla	77.57	0.00e+00	861.00
IUUC-Hsa-045984	Homo sapiens	82.89	0.00e+00	924.00
IUUC-Itr-048890	Ictidomys tridecemlineatus	81.94	0.00e+00	916.00
IUUC-Lch-049700	Latimeria chalumnae	64.20	0.00e+00	669.00
IUUC-Loc-052141	Lepisosteus oculatus	66.54	0.00e+00	762.00
IUUC-Laf-053487	Loxodonta africana	82.13	0.00e+00	915.00
IUUC-Mcc-054682	Macaca mulatta	82.82	0.00e+00	852.00
IUUC-Meu-055937	Macropus eugenii	73.38	0.00e+00	803.00
IUUC-Mga-059953	Meleagris gallopavo	97.34	0.00e+00	1081.00
IUUC-Mmr-061743	Microcebus murinus	82.13	0.00e+00	914.00
IUUC-Mdo-062328	Monodelphis domestica	81.75	0.00e+00	903.00
IUUC-Mmu-063979	Mus musculus	82.32	0.00e+00	918.00
IUUC-Mpu-066750	Mustela putorius furo	81.94	0.00e+00	913.00
IUUC-Mlu-066960	Myotis lucifugus	82.51	0.00e+00	920.00
IUUC-Nle-069690	Nomascus leucogenys	82.70	0.00e+00	836.00
IUUC-Opr-071059	Ochotona princeps	74.90	0.00e+00	827.00
IUUC-Ont-072004	Oreochromis niloticus	62.08	0.00e+00	673.00
IUUC-Oan-073172	Ornithorhynchus anatinus	63.53	0.00e+00	683.00
IUUC-Ola-086599	Oryzias latipes	59.66	0.00e+00	676.00
IUUC-Oga-087980	Otolemur garnettii	81.37	0.00e+00	912.00
IUUC-Oar-089956	Ovis aries	66.03	0.00e+00	667.00
IUUC-Ptr-090598	Pan troglodytes	82.77	0.00e+00	842.00
IUUC-Pan-092387	Papio anubis	83.03	0.00e+00	855.00
IUUC-Psi-093484	Pelodiscus sinensis	87.07	0.00e+00	966.00
IUUC-Pma-094224	Petromyzon marinus	51.09	6.00e-162	563.00
IUUC-Pfo-096149	Poecilia formosa	62.62	0.00e+00	696.00
IUUC-Pab-098097	Pongo abelii	82.70	0.00e+00	923.00
IUUC-Pca-100118	Procavia capensis	82.32	8.00e-171	593.00
IUUC-Pva-103174	Pteropus vampyrus	81.11	3.00e-90	325.00
IUUC-Rno-105350	Rattus norvegicus	81.75	0.00e+00	915.00
IUUC-Sha-106817	Sarcophilus harrisii	85.56	2.00e-93	335.00
IUUC-Sar-113490	Sorex araneus	79.88	8.00e-163	566.00
IUUC-Ssc-115827	Sus scrofa	81.37	0.00e+00	907.00
IUUC-Tru-118644	Takifugu rubripes	60.34	0.00e+00	682.00
IUUC-Tsy-118888	Tarsius syrichta	75.16	0.00e+00	746.00
IUUC-Tni-120060	Tetraodon nigroviridis	55.51	4.00e-167	580.00
IUUC-Ttr-129183	Tursiops truncatus	81.05	0.00e+00	826.00
IUUC-Xtr-132780	Xenopus tropicalis	73.77	0.00e+00	828.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence