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Tag Content
iUUCD ID IUUC-Apl-003677
Ensembl Protein ID ENSAPLP00000003282.1
UniProt Accession U3I7R1; U3I7R1_ANAPL
Genbank Protein ID ENSAPLP00000003282
Protein Name Histone-lysine N-methyltransferase
Genbank Nucleotide ID ADON01048709
Gene Name WHSC1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSAPLG00000003770.1 ENSAPLT00000003882.1 ENSAPLP00000003282.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/PHD 3.90e-16 58.7 838 879
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/PHD
   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           +C vC ++g    sl++Ce C  +fHp+Cl+++    +p+ + w+C++Cr
   Q: 838  WCFVCSKEGG---SLLCCESCPAAFHPDCLNIE----MPDGS-WYCNDCR 879
           8*******99...5*******************....9***8.******8 PP
   
Organism Anas platyrhynchos
Protein Sequence
(Fasta)
MDFSIKRSSQ LLTRKINYIK MKQVPEILGN TNGKTQNCEV NRECSVYLGK AQLSATIQEG 60
VMQKYNGHDA LPFIPADKLK DLTSRVFNGE SGAQDAKLRF EPQEIKGVGT PPNTTPIKNG 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Apl-003677|E3,PHD|Anas platyrhynchos
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGACTTTA GCATCAAAAG AAGCTCTCAA CTGTTAACTC GAAAAATTAA CTACATAAAG 60
ATGAAACAGG TACCAGAGAT CCTTGGAAAT ACCAATGGGA AAACTCAGAA TTGTGAAGTT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Apl-003677|E3,PHD|Anas platyrhynchos
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR006560--AWS_dom
IPR009071--HMG_box_dom
IPR003616--Post-SET_dom
IPR000313--PWWP_dom
IPR001214--SET_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS51215--AWS
PS50118--HMG_BOX_2
PS50868--POST_SET
PS50812--PWWP
PS50280--SET
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
PS50089--ZF_RING_2
Pfam

PF00505--HMG_box
PF00855--PWWP
PF00856--SET
SMART

SM00570--AWS
SM00398--HMG
SM00249--PHD
SM00508--PostSET
SM00293--PWWP
SM00184--RING
SM00317--SET
Gene Ontology

GO:0005634--C:nucleus
GO:0003682--F:chromatin binding
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0043565--F:sequence-specific DNA binding
GO:0008270--F:zinc ion binding
GO:0003289--P:atrial septum primum morphogenesis
GO:0003290--P:atrial septum secundum morphogenesis
GO:0060348--P:bone development
GO:0010452--P:histone H3-K36 methylation
GO:0034770--P:histone H4-K20 methylation
GO:0003149--P:membranous septum morphogenesis
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0048298--P:positive regulation of isotype switching to IgA isotypes
GO:2001032--P:regulation of double-strand break repair via nonhomologous end joining
GO:0070201--P:regulation of establishment of protein localization
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002181 Ailuropoda melanoleuca 81.76 0.00e+00 2127.00
IUUC-Aca-004278 Anolis carolinensis 80.47 0.00e+00 1524.00
IUUC-Ame-011932 Astyanax mexicanus 70.91 0.00e+00 1070.00
IUUC-Bta-012522 Bos taurus 76.96 0.00e+00 2003.00
IUUC-Cja-018908 Callithrix jacchus 80.16 0.00e+00 2083.00
IUUC-Cfa-020894 Canis familiaris 81.03 0.00e+00 2150.00
IUUC-Cpo-021982 Cavia porcellus 78.95 0.00e+00 2089.00
IUUC-Csa-023807 Chlorocebus sabaeus 81.03 0.00e+00 2119.00
IUUC-Cho-024405 Choloepus hoffmanni 61.25 1.00e-179 623.00
IUUC-Dre-027492 Danio rerio 73.78 0.00e+00 1115.00
IUUC-Dno-030020 Dasypus novemcinctus 78.11 0.00e+00 1837.00
IUUC-Dor-031103 Dipodomys ordii 73.57 0.00e+00 1880.00
IUUC-Ete-032488 Echinops telfairi 74.90 0.00e+00 1905.00
IUUC-Eca-034066 Equus caballus 82.33 0.00e+00 2192.00
IUUC-Eeu-035199 Erinaceus europaeus 63.45 0.00e+00 654.00
IUUC-Fca-035434 Felis catus 78.08 0.00e+00 1763.00
IUUC-Fal-037113 Ficedula albicollis 94.34 0.00e+00 2612.00
IUUC-Gmo-039686 Gadus morhua 68.67 0.00e+00 1035.00
IUUC-Gga-040273 Gallus gallus 94.63 0.00e+00 2523.00
IUUC-Gac-042123 Gasterosteus aculeatus 50.68 0.00e+00 1249.00
IUUC-Ggo-044643 Gorilla gorilla 80.80 0.00e+00 2130.00
IUUC-Hsa-046380 Homo sapiens 80.98 0.00e+00 2108.00
IUUC-Itr-048658 Ictidomys tridecemlineatus 85.07 0.00e+00 1334.00
IUUC-Lch-050217 Latimeria chalumnae 68.18 0.00e+00 1796.00
IUUC-Lpe-051201 Leersia perrieri 26.96 2.00e-11 63.90
IUUC-Loc-052766 Lepisosteus oculatus 59.27 0.00e+00 1325.00
IUUC-Laf-053780 Loxodonta africana 81.45 0.00e+00 2174.00
IUUC-Mcc-054928 Macaca mulatta 81.18 0.00e+00 2148.00
IUUC-Meu-056184 Macropus eugenii 77.94 0.00e+00 809.00
IUUC-Mga-059576 Meleagris gallopavo 94.75 0.00e+00 2515.00
IUUC-Mmr-061045 Microcebus murinus 81.44 0.00e+00 2180.00
IUUC-Mdo-062576 Monodelphis domestica 85.14 0.00e+00 2259.00
IUUC-Mmu-063640 Mus musculus 79.01 0.00e+00 2076.00
IUUC-Mac-065303 Musa acuminata 28.57 8.00e-11 62.00
IUUC-Mpu-066512 Mustela putorius furo 81.99 0.00e+00 2132.00
IUUC-Mlu-067280 Myotis lucifugus 75.54 0.00e+00 1041.00
IUUC-Nle-069896 Nomascus leucogenys 81.34 0.00e+00 2038.00
IUUC-Ont-072197 Oreochromis niloticus 74.18 0.00e+00 1056.00
IUUC-Oan-072724 Ornithorhynchus anatinus 82.67 0.00e+00 1415.00
IUUC-Ocu-074758 Oryctolagus cuniculus 78.59 0.00e+00 2039.00
IUUC-Obr-076122 Oryza brachyantha 27.38 5.00e-11 60.80
IUUC-Ogu-078030 Oryza glumaepatula 28.93 2.00e-13 69.70
IUUC-Olo-080702 Oryza longistaminata 41.47 1.00e-44 174.00
IUUC-Opu-083371 Oryza punctata 44.72 9.00e-46 178.00
IUUC-Oga-088702 Otolemur garnettii 81.63 0.00e+00 1889.00
IUUC-Oar-089736 Ovis aries 71.27 0.00e+00 1758.00
IUUC-Ptr-091055 Pan troglodytes 80.91 0.00e+00 2110.00
IUUC-Pan-092752 Papio anubis 87.78 0.00e+00 1322.00
IUUC-Psi-093620 Pelodiscus sinensis 92.55 0.00e+00 2490.00
IUUC-Pfo-097464 Poecilia formosa 50.33 0.00e+00 1212.00
IUUC-Pab-098051 Pongo abelii 81.13 0.00e+00 2143.00
IUUC-Pop-099927 Populus trichocarpa 28.27 2.00e-11 63.90
IUUC-Pca-100273 Procavia capensis 80.33 0.00e+00 2125.00
IUUC-Pva-102473 Pteropus vampyrus 70.65 0.00e+00 1761.00
IUUC-Rno-105056 Rattus norvegicus 79.67 0.00e+00 2100.00
IUUC-Sha-107494 Sarcophilus harrisii 85.58 0.00e+00 2235.00
IUUC-Sit-110333 Setaria italica 27.81 6.00e-10 58.90
IUUC-Sar-113310 Sorex araneus 81.12 0.00e+00 1660.00
IUUC-Sbi-114581 Sorghum bicolor 31.48 1.00e-08 53.50
IUUC-Ssc-116344 Sus scrofa 75.32 0.00e+00 1980.00
IUUC-Tgu-116786 Taeniopygia guttata 96.40 0.00e+00 2550.00
IUUC-Tru-117638 Takifugu rubripes 51.20 0.00e+00 1246.00
IUUC-Tsy-118937 Tarsius syrichta 85.91 0.00e+00 1410.00
IUUC-Tae-125237 Triticum aestivum 30.87 3.00e-06 45.10
IUUC-Tbe-127291 Tupaia belangeri 78.60 0.00e+00 1362.00
IUUC-Ttr-129017 Tursiops truncatus 72.39 0.00e+00 1543.00
IUUC-Xtr-132673 Xenopus tropicalis 69.38 0.00e+00 1806.00
IUUC-Xma-133695 Xiphophorus maculatus 68.42 0.00e+00 1026.00
Created Date 25-Jun-2017

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