iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004532

UUCD1 version

UUC-AnC-00989

Ensembl Protein ID

ENSACAP00000004936.3

UniProt Accession

G1KDH8; G1KDH8_ANOCA

Protein Name

Uncharacterized protein

Gene Name

USP11

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000004813.3	ENSACAT00000005049.3	ENSACAP00000004936.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.60e-94	316.8	243	865

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           +Gl+NlgNtC+mNS+LQcLsn+p+l+e++l+  +  +ln +np ++kge+++++++l+++ w+++++++ pr+++++++++a++f gy+
   Q: 243  CGLTNLGNTCFMNSALQCLSNVPPLTEYFLNnCYLDELNFSNPLGMKGEIAEAYADLIKQQWSGHHRSIVPRMFKTKVGHFASQFLGYQ 331
           7******************************999******************************************************* PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           q+D+qE+l+flld+l+e+l++ k+k++ e+++++   ++de     a++++k++n+s+i+d+F+g +ks+++c+ec++vs++++pf++l
   Q: 332  QHDSQELLSFLLDGLHEDLNRIKKKEYIELKDAA--GRPDEevaeeAWRNHKRRNNSIIVDIFHGLFKSTLVCPECGKVSVTFDPFCYL 418
           *********************9999999998776..3333334555******************************************* PP
   S: 173  slpvpgkeetkke............................................................................ 185
           s p+p ++++ +e                                                                            
   Q: 419  SAPLPVSKDRVMEvffvsmdpskkpeqhrlivpkagkvldlclalskhtevpaermmvadvfshrfykiyqmeeslscildrddifiye 507
           ********99999**************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 508  vsvslledpstadavvlpvylrehaqgrdysdtyygvvlfghpllvsvprdqlsweaiyqlllhrlsryvtqpdseeeedqseegedee 596
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 597  eeeeeeeeeeeeeeeeeeeeeetaaegsnsqepsleanqakrkcrlpqkrqkllftlhhvnsngtsdrmasqdeirssqpylamdwdsd 685
           ***************************************************************************************** PP
   S: 186  .............................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqks 245
                                        +lq+c+e ft+ e+le+en +yc++ckk+q a+kkl+l++lPe+Li+hLkRfs+++   s
   Q: 686  mkkryyneaeaegyvkhdcmgymlkknpvKLQECIELFTTVETLEEENPWYCPTCKKHQLATKKLDLWSLPEILIIHLKRFSYTK--FS 772
           *********************************************************************************8866..89 PP
   S: 246  rekinkkvefple..LdlspfctspeekqkekkkYeLiavvvHsG.slssGHY.vayvknekgk.WllfdDskVtevkeeevleetgst 329
           rek+++ vefp++  L+ s f  +p++++   k    +  ++ s  ++ssGH  +++++n++ + W++fdDs+V++v+++++++   + 
   Q: 773  REKLDTLVEFPIQqdLNFSDFIGKPQKDS--LKASLVYQFIYASNlQISSGHVdTTFARNKDSGtWFYFDDSSVSAVSKSQIES---KA 856
           ***********776799999****99886..3333344455666699*****8688888866668*******************...** PP
   S: 330  aYvlfYkrr 338
           aYvlfY+r+
   Q: 857  AYVLFYQRQ 865
           *******96 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MAAERGLPGL EAQRRQVEGE GPAQPGLERP LRAGEKWYLL ENHWYKQWKA YVESGNQNSS 60
SFPGRINNAE LFEDLESYRL KDRLVEHEEY VLVPEEVWNK LVSWYGTEHD QPAIERKVVD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACCTATCAC GGCCGGGCGG AAGTGGGCGG GCGGGTCCCG AGGAGCCGGG AGTTGCGGCG 60
GGGGAAAGAA GGCATCCTCG TTTGCTGGCT TCCGGGCTGG ATGGTGGGCG ATGGCGGCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00972--USP_1
PS50235--USP_3

Pfam

PF06337--DUSP
PF14836--Ubiquitin_3
PF00443--UCH

SMART

SM00695--DUSP

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001760	Ailuropoda melanoleuca	64.99	0.00e+00	1154.00
IUUC-Atr-002675	Amborella trichopoda	30.14	3.00e-96	346.00
IUUC-Ago-007911	Ashbya gossypii	36.88	2.00e-62	234.00
IUUC-Ame-011858	Astyanax mexicanus	66.48	0.00e+00	769.00
IUUC-Bgr-012277	Blumeria graminis	39.11	5.00e-63	237.00
IUUC-Bta-013284	Bos taurus	66.52	0.00e+00	1179.00
IUUC-Bdi-014523	Brachypodium distachyon	33.05	3.00e-117	416.00
IUUC-Cja-019746	Callithrix jacchus	65.93	0.00e+00	1151.00
IUUC-Cfa-020134	Canis familiaris	66.82	0.00e+00	1170.00
IUUC-Cpo-022535	Cavia porcellus	61.41	0.00e+00	1108.00
IUUC-Csa-023828	Chlorocebus sabaeus	66.05	0.00e+00	1166.00
IUUC-Dre-027398	Danio rerio	67.48	0.00e+00	816.00
IUUC-Dno-028853	Dasypus novemcinctus	66.54	0.00e+00	1011.00
IUUC-Dor-030384	Dipodomys ordii	63.86	0.00e+00	1123.00
IUUC-Eca-033271	Equus caballus	67.36	0.00e+00	1162.00
IUUC-Fca-036012	Felis catus	64.51	0.00e+00	1157.00
IUUC-Fox-037986	Fusarium oxysporum	44.12	3.00e-62	234.00
IUUC-Fso-038291	Fusarium solani	45.22	4.00e-65	243.00
IUUC-Gmo-038697	Gadus morhua	58.56	0.00e+00	682.00
IUUC-Gac-042574	Gasterosteus aculeatus	56.12	0.00e+00	920.00
IUUC-Hsa-046551	Homo sapiens	66.17	0.00e+00	1167.00
IUUC-Itr-048915	Ictidomys tridecemlineatus	65.25	0.00e+00	1147.00
IUUC-Kpa-049332	Komagataella pastoris	33.63	1.00e-71	265.00
IUUC-Laf-054561	Loxodonta africana	65.27	0.00e+00	1147.00
IUUC-Mcc-054881	Macaca mulatta	66.05	0.00e+00	1163.00
IUUC-Meu-056749	Macropus eugenii	77.80	0.00e+00	894.00
IUUC-Mla-058848	Melampsora laricipopulina	42.54	5.00e-70	259.00
IUUC-Mmr-061400	Microcebus murinus	67.17	0.00e+00	1174.00
IUUC-Mdo-062470	Monodelphis domestica	75.25	0.00e+00	800.00
IUUC-Mmu-063241	Mus musculus	63.17	0.00e+00	1119.00
IUUC-Mpu-066507	Mustela putorius furo	64.77	0.00e+00	1173.00
IUUC-Mlu-066961	Myotis lucifugus	62.37	0.00e+00	1082.00
IUUC-Nle-069284	Nomascus leucogenys	66.17	0.00e+00	1169.00
IUUC-Ont-071847	Oreochromis niloticus	61.21	0.00e+00	1014.00
IUUC-Oan-073387	Ornithorhynchus anatinus	77.43	0.00e+00	911.00
IUUC-Ocu-074066	Oryctolagus cuniculus	65.70	0.00e+00	1159.00
IUUC-Olu-087717	Ostreococcus lucimarinus	35.64	7.00e-104	371.00
IUUC-Oga-088424	Otolemur garnettii	66.63	0.00e+00	1169.00
IUUC-Oar-089732	Ovis aries	67.44	0.00e+00	1146.00
IUUC-Pan-092292	Papio anubis	66.17	0.00e+00	1166.00
IUUC-Pfo-096414	Poecilia formosa	69.27	0.00e+00	839.00
IUUC-Pab-098779	Pongo abelii	60.09	0.00e+00	979.00
IUUC-Pca-100851	Procavia capensis	71.37	0.00e+00	745.00
IUUC-Pva-103244	Pteropus vampyrus	65.17	0.00e+00	1123.00
IUUC-Ptt-103847	Puccinia triticina	35.97	3.00e-63	237.00
IUUC-Rno-105100	Rattus norvegicus	63.63	0.00e+00	1130.00
IUUC-Sce-106170	Saccharomyces cerevisiae	34.81	5.00e-62	233.00
IUUC-Sha-107502	Sarcophilus harrisii	75.40	0.00e+00	881.00
IUUC-Spo-108291	Schizosaccharomyces pombe	32.72	2.00e-78	286.00
IUUC-Ssc-116345	Sus scrofa	64.59	0.00e+00	1184.00
IUUC-Tru-117788	Takifugu rubripes	60.71	0.00e+00	971.00
IUUC-Tsy-119414	Tarsius syrichta	60.86	0.00e+00	836.00
IUUC-Tre-121888	Trichoderma reesei	44.49	3.00e-62	234.00
IUUC-Tvi-122422	Trichoderma virens	42.65	2.00e-58	221.00
IUUC-Tbe-128081	Tupaia belangeri	70.02	0.00e+00	790.00
IUUC-Ttr-128502	Tursiops truncatus	63.09	0.00e+00	1076.00
IUUC-Xma-133838	Xiphophorus maculatus	57.30	0.00e+00	941.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence