iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066507

Ensembl Protein ID

ENSMPUP00000013063.1

UniProt Accession

M3YP06; M3YP06_MUSPF

Genbank Protein ID

ENSMPUP00000013063

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01038402

Gene Name

USP11

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000013161.1	ENSMPUT00000013274.1	ENSMPUP00000013063.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	6.50e-112	374.0	268	889

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           +Gl+NlgNtC+mNS+LQcLsn+p+l+e++l+ ++ e+ln  np ++kge+++++++l+++ w+++++++ p+ ++++++++a++f gy+
   Q: 268  CGLTNLGNTCFMNSALQCLSNVPQLTEYFLKnRYLEELNFCNPLGMKGEIAEAYADLVKQAWSGHHRSIVPHVFKTKVGHFASQFLGYQ 356
           7*****************************999******************************************************** PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde...aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
           q+D+qE+l+flld+l+e+l++ k+k++ e+++++ +  ++    a++++k++n+s+i+d+F+g +ks+++c++c+nvs++++pf++ls+
   Q: 357  QHDSQELLSFLLDGLHEDLNRVKKKEYVELCDAAGRPDQEVaqeAWQNHKRRNDSVIVDTFHGLFKSTLVCPDCGNVSVTFDPFCYLSV 445
           *****************************998874333322555********************************************* PP
   S: 175  pvpgkeetkke.............................................................................. 185
           p+p ++++ +e                                                                              
   Q: 446  PLPVSHKRVMEvffvsmdprrkpeqhrlvvpkkgkisdlcvalakhtgmspermmvadvfshrfykiyqleeslssildrddifiyevs 534
           ******99988****************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 535  grsaigentredvvlpiylrertpardynnsyyglmlfghpllvsvprdrlswdalyhillyrlsryvtrpssddeddgdekdmedkdn 623
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 624  ipkpghvaggssqdsgpeqagpssgvaggsrapvdsspgpshwpqrarrkhlftlqtvnsngtsdrstfnedthaqpyiaidwepemkk 712
           ***************************************************************************************** PP
   S: 186  ..........................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrek 248
                                      lq+c+e ft+ e+le+en +yc++ck++q a+kkl+l+ lPe+Li+hLkRfs+++   srek
   Q: 713  ryydeveaegyvkhdcvgyvlkkapvRLQECIELFTTVETLEKENPWYCPTCKQHQLATKKLDLWMLPETLIIHLKRFSYTK--FSREK 799
           ******************************************************************************8866..89*** PP
   S: 249  inkkvefple.Ldlspfctspeekqke.kkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetgstaYvlf 334
           +++ vefp++ Ld s+f+++p+++++   +kY+Liav +H+G+l+ GHY++++ n ++g+W +fdD++V++v+e+++++   + aYvlf
   Q: 800  LDTLVEFPIRdLDFSEFVIKPQNESAPeLYKYDLIAVSNHYGGLRDGHYTTFACNkDSGQWHYFDDNSVSPVTENQIES---KAAYVLF 885
           ******************999887754489*********************988834566*******************...******* PP
   S: 335  Ykrr 338
           Y+r+
   Q: 886  YQRQ 889
           **96 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

DAVAARGGRT VMAAVAANVA AAAEDQEPQR EAVPSLESQR LQIENGESGR GRPLRAGESW 60
FLVVRHWYKQ WEAYVQGGDK DSGTFPGCIN NADLFEDQVN WHLRKGLVEG EDYVLLPAAA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATGCGGTAG CTGCAAGAGG AGGGCGAACG GTGATGGCGG CGGTCGCAGC GAATGTGGCG 60
GCTGCGGCCG AGGACCAAGA GCCGCAGCGC GAAGCTGTGC CGAGCCTCGA GAGCCAGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR029346--USP_C
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF14836--Ubiquitin_3
PF00443--UCH
PF14533--USP7_C2

SMART

SM00695--DUSP

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001760	Ailuropoda melanoleuca	94.82	0.00e+00	1740.00
IUUC-Aca-004532	Anolis carolinensis	64.77	0.00e+00	1147.00
IUUC-Afl-008507	Aspergillus flavus	34.50	2.00e-54	208.00
IUUC-Afu-008878	Aspergillus fumigatus	38.99	2.00e-56	214.00
IUUC-Aor-009949	Aspergillus oryzae	34.06	2.00e-53	204.00
IUUC-Ate-010323	Aspergillus terreus	37.14	2.00e-57	218.00
IUUC-Bta-013284	Bos taurus	91.86	0.00e+00	1624.00
IUUC-Cja-019746	Callithrix jacchus	83.31	0.00e+00	1498.00
IUUC-Cfa-020134	Canis familiaris	95.04	0.00e+00	1730.00
IUUC-Cpo-022535	Cavia porcellus	77.25	0.00e+00	1461.00
IUUC-Csa-023828	Chlorocebus sabaeus	84.09	0.00e+00	1534.00
IUUC-Dno-028853	Dasypus novemcinctus	89.27	0.00e+00	1406.00
IUUC-Dor-030384	Dipodomys ordii	80.18	0.00e+00	1446.00
IUUC-Eca-033271	Equus caballus	94.10	0.00e+00	1672.00
IUUC-Fca-036012	Felis catus	95.11	0.00e+00	1743.00
IUUC-Gac-042574	Gasterosteus aculeatus	55.82	0.00e+00	917.00
IUUC-Hsa-046551	Homo sapiens	84.09	0.00e+00	1532.00
IUUC-Itr-048915	Ictidomys tridecemlineatus	80.18	0.00e+00	1435.00
IUUC-Kpa-049332	Komagataella pastoris	32.47	1.00e-68	255.00
IUUC-Laf-054561	Loxodonta africana	85.76	0.00e+00	1598.00
IUUC-Mcc-054881	Macaca mulatta	83.76	0.00e+00	1531.00
IUUC-Meu-056749	Macropus eugenii	82.16	0.00e+00	922.00
IUUC-Mla-058848	Melampsora laricipopulina	41.99	2.00e-72	268.00
IUUC-Mvi-060324	Microbotryum violaceum	32.30	1.00e-82	301.00
IUUC-Mmr-061400	Microcebus murinus	85.21	0.00e+00	1554.00
IUUC-Mmu-063241	Mus musculus	76.64	0.00e+00	1410.00
IUUC-Mlu-066961	Myotis lucifugus	84.04	0.00e+00	1528.00
IUUC-Nfi-068330	Neosartorya fischeri	38.46	4.00e-55	211.00
IUUC-Nle-069284	Nomascus leucogenys	83.98	0.00e+00	1532.00
IUUC-Ont-071847	Oreochromis niloticus	59.15	0.00e+00	993.00
IUUC-Oan-073387	Ornithorhynchus anatinus	71.30	0.00e+00	1239.00
IUUC-Ocu-074066	Oryctolagus cuniculus	83.10	0.00e+00	1492.00
IUUC-Oga-088424	Otolemur garnettii	84.65	0.00e+00	1531.00
IUUC-Oar-089732	Ovis aries	87.61	0.00e+00	1621.00
IUUC-Pan-092292	Papio anubis	84.40	0.00e+00	1530.00
IUUC-Pab-098779	Pongo abelii	76.19	0.00e+00	1313.00
IUUC-Pca-100851	Procavia capensis	84.78	0.00e+00	900.00
IUUC-Pva-103244	Pteropus vampyrus	90.22	0.00e+00	1633.00
IUUC-Ptt-103847	Puccinia triticina	36.29	2.00e-64	241.00
IUUC-Rno-105100	Rattus norvegicus	77.44	0.00e+00	1419.00
IUUC-Sha-107502	Sarcophilus harrisii	80.79	0.00e+00	915.00
IUUC-Spo-108291	Schizosaccharomyces pombe	32.61	8.00e-76	278.00
IUUC-Smo-109356	Selaginella moellendorffii	39.88	6.00e-115	407.00
IUUC-Sar-113704	Sorex araneus	76.37	0.00e+00	807.00
IUUC-Ssc-116345	Sus scrofa	93.59	0.00e+00	1740.00
IUUC-Tru-117788	Takifugu rubripes	58.08	0.00e+00	948.00
IUUC-Tsy-119414	Tarsius syrichta	76.81	0.00e+00	1078.00
IUUC-Tvi-122422	Trichoderma virens	41.54	1.00e-57	218.00
IUUC-Tme-127062	Tuber melanosporum	33.85	4.00e-80	293.00
IUUC-Tbe-128081	Tupaia belangeri	85.71	0.00e+00	970.00
IUUC-Ttr-128502	Tursiops truncatus	90.23	0.00e+00	1639.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence