iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Dme-031964

UUCD1 version

UUC-DrM-00013

Ensembl Protein ID

FBpp0112409

UniProt Accession

Q6GKZ1; Q500X7; Q7PLC2; Q6GKZ1_DROME

Genbank Protein ID

AAT47774.1; AAY33506.2; EAA46324.2; EAA46325.2

Protein Name

AT19737p; GH26310p; Kelch like family member 10, isoform A; Kelch like family member 10, isoform B

Genbank Nucleotide ID

BT014923; BT022090; CP007081; CP007081

Gene Name

klhl10; anon-WO0140519.152; DmelCG12423; CG12423; Dmel_CG12423

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
FBgn0040038	FBtr0113686	FBpp0112409

Annotation

mRNA Expression
ArrayExpress
DNA & RNA Element
RAID2
Protein-protein Interaction
IID	iRefIndex	PINA
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 adaptor/Cullin RING/BCR/BTB_3-box	BTB_3-box	17880263

Classification

Family	E-value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.40e-10	40.6	82	159
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	9.10e-08	31.4	192	223

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmelees..........ksklmveikdvqpevfrallkFlYtgklden 68
           +D ++ vg+ +f++h+++++++Ss+F+a f++   ++          k+++ ++i +v+   ++ ++++ Y  + +++
   Q: 82   CDAQISVGEDVFNVHRAIMCSCSSYFRAQFTGFNADTpgcvdgsdakKNNNFIHIPGVSSCIMNCVIQYAYLRQTNIS 159
           899***************************7755588999999***9889*********************9988765 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           +eNc++i+ fA+  +++dL+++a++++l+ F+
   Q: 192  PENCVSIMGFARFRFLEDLHLKARNYTLRYFT 223
           89***************************996 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MSRNQNESNL LDINEDLPFA LALPPVSMDS LQLNADGNSP EDKTLGIGRK TILNAHTKSL 60
APIVSDEALN TLNELREQNL LCDAQISVGE DVFNVHRAIM CSCSSYFRAQ FTGFNADTPG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCAAAAGCAG ACTGGGTGAA AACTGCCTTC GAACTTCTGC AATAAAACGG CTCCTAACCC 60
GTCCTTAGAG GCATCTGTAT GAAGTTCGGT TTCTGCTTCT CGTGAGTAGA TCCTCAATAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0880--Kelch repeat
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0006919--P:activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0016567--P:protein ubiquitination
GO:0007291--P:sperm individualization

KEGG

dme:Dmel_CG12423

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001576	Ailuropoda melanoleuca	46.56	7.00e-154	536.00
IUUC-Atr-002726	Amborella trichopoda	35.22	3.00e-45	176.00
IUUC-Apl-003525	Anas platyrhynchos	45.30	2.00e-155	541.00
IUUC-Aca-005295	Anolis carolinensis	45.21	1.00e-129	456.00
IUUC-Ang-009879	Aspergillus niger	29.17	5.00e-11	61.20
IUUC-Ame-010953	Astyanax mexicanus	36.28	9.00e-117	413.00
IUUC-Bta-013447	Bos taurus	46.56	7.00e-154	536.00
IUUC-Cja-019472	Callithrix jacchus	51.83	7.00e-111	392.00
IUUC-Cfa-020332	Canis familiaris	46.38	7.00e-153	533.00
IUUC-Cpo-021949	Cavia porcellus	46.56	9.00e-154	536.00
IUUC-Csa-023573	Chlorocebus sabaeus	45.63	1.00e-153	535.00
IUUC-Cho-024451	Choloepus hoffmanni	45.92	2.00e-134	471.00
IUUC-Cin-025680	Ciona intestinalis	42.31	3.00e-130	457.00
IUUC-Csv-026085	Ciona savignyi	41.38	3.00e-127	447.00
IUUC-Dre-028411	Danio rerio	43.72	1.00e-138	485.00
IUUC-Dno-029608	Dasypus novemcinctus	46.56	9.00e-154	536.00
IUUC-Dor-030200	Dipodomys ordii	46.72	4.00e-142	497.00
IUUC-Ete-032475	Echinops telfairi	44.27	2.00e-142	498.00
IUUC-Eca-034237	Equus caballus	46.56	7.00e-154	536.00
IUUC-Fca-036271	Felis catus	46.56	8.00e-154	536.00
IUUC-Fal-037352	Ficedula albicollis	43.60	8.00e-141	493.00
IUUC-Gga-040205	Gallus gallus	46.02	7.00e-153	533.00
IUUC-Gac-041982	Gasterosteus aculeatus	39.29	3.00e-126	444.00
IUUC-Gma-043533	Glycine max	32.75	2.00e-37	149.00
IUUC-Ggo-045241	Gorilla gorilla	45.45	2.00e-153	535.00
IUUC-Hsa-047022	Homo sapiens	45.63	7.00e-154	536.00
IUUC-Itr-048079	Ictidomys tridecemlineatus	46.56	8.00e-154	536.00
IUUC-Lch-050637	Latimeria chalumnae	45.27	1.00e-154	538.00
IUUC-Loc-052412	Lepisosteus oculatus	42.11	9.00e-130	456.00
IUUC-Laf-054118	Loxodonta africana	46.56	8.00e-154	536.00
IUUC-Mcc-055476	Macaca mulatta	42.71	2.00e-134	471.00
IUUC-Meu-056158	Macropus eugenii	46.56	8.00e-154	536.00
IUUC-Mga-059634	Meleagris gallopavo	45.83	1.00e-151	529.00
IUUC-Mmr-061217	Microcebus murinus	42.68	2.00e-129	455.00
IUUC-Mdo-062138	Monodelphis domestica	46.56	1.00e-153	535.00
IUUC-Mmu-063769	Mus musculus	46.56	8.00e-154	536.00
IUUC-Mpu-066045	Mustela putorius furo	46.56	7.00e-154	536.00
IUUC-Mlu-067348	Myotis lucifugus	46.38	1.00e-152	532.00
IUUC-Nle-069331	Nomascus leucogenys	45.63	3.00e-153	534.00
IUUC-Opr-071203	Ochotona princeps	45.68	1.00e-146	512.00
IUUC-Ont-071882	Oreochromis niloticus	33.17	2.00e-87	316.00
IUUC-Ocu-073757	Oryctolagus cuniculus	44.87	9.00e-154	536.00
IUUC-Obr-076712	Oryza brachyantha	28.46	6.00e-34	138.00
IUUC-Ogl-077725	Oryza glaberrima	28.81	3.00e-32	132.00
IUUC-Ogu-078293	Oryza glumaepatula	29.45	2.00e-13	69.70
IUUC-Oin-080100	Oryza indica	29.24	1.00e-32	134.00
IUUC-Ome-081207	Oryza meridionalis	29.45	2.00e-13	69.70
IUUC-Oni-082785	Oryza nivara	29.45	2.00e-13	69.30
IUUC-Oru-084871	Oryza rufipogon	29.45	2.00e-13	69.30
IUUC-Ola-086791	Oryzias latipes	37.86	8.00e-107	380.00
IUUC-Oga-088676	Otolemur garnettii	46.74	4.00e-154	537.00
IUUC-Oar-089804	Ovis aries	46.56	2.00e-153	535.00
IUUC-Ptr-090767	Pan troglodytes	45.63	9.00e-154	536.00
IUUC-Pan-092856	Papio anubis	45.63	1.00e-153	535.00
IUUC-Psi-094041	Pelodiscus sinensis	45.89	1.00e-156	545.00
IUUC-Ppa-095209	Physcomitrella patens	27.51	4.00e-19	88.20
IUUC-Pfo-096382	Poecilia formosa	40.07	2.00e-124	438.00
IUUC-Pab-097694	Pongo abelii	45.45	1.00e-153	535.00
IUUC-Pca-100693	Procavia capensis	45.38	2.00e-119	422.00
IUUC-Pva-102153	Pteropus vampyrus	51.06	2.00e-117	415.00
IUUC-Rno-105012	Rattus norvegicus	46.56	8.00e-154	536.00
IUUC-Sha-106593	Sarcophilus harrisii	46.56	9.00e-154	536.00
IUUC-Smo-109140	Selaginella moellendorffii	25.17	3.00e-09	54.70
IUUC-Sit-109955	Setaria italica	27.75	4.00e-12	64.70
IUUC-Sar-113188	Sorex araneus	46.21	2.00e-147	515.00
IUUC-Sbi-114612	Sorghum bicolor	29.25	6.00e-36	145.00
IUUC-Tgu-116852	Taeniopygia guttata	43.33	7.00e-139	486.00
IUUC-Tru-118098	Takifugu rubripes	36.16	9.00e-106	376.00
IUUC-Tsy-119581	Tarsius syrichta	41.45	2.00e-123	434.00
IUUC-Tni-120002	Tetraodon nigroviridis	39.28	1.00e-107	382.00
IUUC-Tca-121074	Theobroma cacao	30.86	2.00e-37	150.00
IUUC-Tbe-127778	Tupaia belangeri	43.39	2.00e-133	468.00
IUUC-Ttr-128966	Tursiops truncatus	43.36	1.00e-140	492.00
IUUC-Vpa-130421	Vicugna pacos	51.83	1.00e-110	392.00
IUUC-Xtr-131853	Xenopus tropicalis	40.00	2.00e-127	448.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence