iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.80e-19	69.6	173	240
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	8.80e-09	34.6	272	302

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           +Dvilv g+++++ah++vL++ S++F a+f+++ +e + ++++++++v+p ++  l+++ Ytg+l+++e
   Q: 173  CDVILVAGDRRIPAHRLVLSSVSDYFAAMFTNDVREAR-QEEIKMEGVEPNSLWSLIQYAYTGRLELKE 240
           9************************************9.**************************9986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           ++Nclgi++fAd+ +c+dL+++a++++  hF
   Q: 272  PSNCLGIRSFADAQGCTDLHKVAHNYTMEHF 302
           89************************98777 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MSGSRKEFDV KQILKIRWRW FGHQASSNSS VDSQQGEFWS RGQTGANGGR KFLDPCNLQL 60
PLASIGYRRS SQLDFQNSPS WPMASTSDVP AFEFTAEGCG GAHWLDRPEV DDGTSEEENE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATCCTTTGTT CTTTACAGTC TGATATATTG GGATGAAAGT AAATGTGGAT ATATATCCCA 60
ACGATTTATT TCCCTTTAAA GCTGTTTGTT GGCTACAGCG GGGAATAGAC TCCTCTTGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination

KEGG

rno:305351

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000220	Aegilops tauschii	32.92	6.00e-39	156.00
IUUC-Aml-001239	Ailuropoda melanoleuca	98.78	0.00e+00	1196.00
IUUC-Apl-003930	Anas platyrhynchos	91.64	0.00e+00	1176.00
IUUC-Aca-004826	Anolis carolinensis	90.55	0.00e+00	1305.00
IUUC-Ame-011037	Astyanax mexicanus	80.40	0.00e+00	837.00
IUUC-Bta-013448	Bos taurus	97.32	0.00e+00	1382.00
IUUC-Bdi-014143	Brachypodium distachyon	34.87	2.00e-42	167.00
IUUC-Cja-019953	Callithrix jacchus	97.60	0.00e+00	1401.00
IUUC-Cfa-020335	Canis familiaris	98.02	0.00e+00	1406.00
IUUC-Cpo-021385	Cavia porcellus	97.60	0.00e+00	1399.00
IUUC-Csa-023109	Chlorocebus sabaeus	97.60	0.00e+00	1400.00
IUUC-Cho-024402	Choloepus hoffmanni	97.40	0.00e+00	1355.00
IUUC-Csv-026377	Ciona savignyi	65.19	0.00e+00	763.00
IUUC-Dre-028618	Danio rerio	82.75	0.00e+00	995.00
IUUC-Dno-029854	Dasypus novemcinctus	76.19	0.00e+00	899.00
IUUC-Dme-032222	Drosophila melanogaster	57.86	0.00e+00	673.00
IUUC-Eca-034002	Equus caballus	98.03	0.00e+00	1405.00
IUUC-Fca-035953	Felis catus	91.53	0.00e+00	1300.00
IUUC-Fal-037331	Ficedula albicollis	92.66	0.00e+00	1190.00
IUUC-Gmo-039309	Gadus morhua	76.27	0.00e+00	909.00
IUUC-Gga-041137	Gallus gallus	95.95	0.00e+00	1159.00
IUUC-Gac-042162	Gasterosteus aculeatus	77.86	0.00e+00	894.00
IUUC-Gma-043533	Glycine max	32.38	3.00e-37	150.00
IUUC-Ggo-044697	Gorilla gorilla	97.69	0.00e+00	1367.00
IUUC-Hsa-047037	Homo sapiens	97.13	0.00e+00	1367.00
IUUC-Hvu-047224	Hordeum vulgare	31.93	2.00e-38	154.00
IUUC-Itr-048921	Ictidomys tridecemlineatus	75.48	0.00e+00	900.00
IUUC-Lch-050568	Latimeria chalumnae	87.75	0.00e+00	1263.00
IUUC-Lpe-051276	Leersia perrieri	28.24	2.00e-40	161.00
IUUC-Loc-052139	Lepisosteus oculatus	79.42	0.00e+00	1169.00
IUUC-Laf-054213	Loxodonta africana	97.88	0.00e+00	1404.00
IUUC-Mcc-054988	Macaca mulatta	97.74	0.00e+00	1401.00
IUUC-Mga-059394	Meleagris gallopavo	86.48	0.00e+00	1244.00
IUUC-Mmr-061186	Microcebus murinus	98.44	0.00e+00	1057.00
IUUC-Mdo-062687	Monodelphis domestica	95.77	0.00e+00	1372.00
IUUC-Mmu-063695	Mus musculus	98.73	0.00e+00	1414.00
IUUC-Mpu-065886	Mustela putorius furo	93.25	0.00e+00	1397.00
IUUC-Mlu-067820	Myotis lucifugus	97.46	0.00e+00	1398.00
IUUC-Nle-069647	Nomascus leucogenys	97.60	0.00e+00	1402.00
IUUC-Opr-070814	Ochotona princeps	96.67	0.00e+00	1345.00
IUUC-Ont-071631	Oreochromis niloticus	77.47	0.00e+00	906.00
IUUC-Oan-073455	Ornithorhynchus anatinus	90.89	0.00e+00	1185.00
IUUC-Ocu-074469	Oryctolagus cuniculus	75.30	0.00e+00	898.00
IUUC-Ogu-078442	Oryza glumaepatula	25.57	2.00e-12	67.80
IUUC-Olo-080536	Oryza longistaminata	34.52	7.00e-38	153.00
IUUC-Oni-082519	Oryza nivara	24.68	5.00e-14	73.20
IUUC-Oga-088236	Otolemur garnettii	96.90	0.00e+00	1387.00
IUUC-Oar-089243	Ovis aries	97.46	0.00e+00	1392.00
IUUC-Ptr-090722	Pan troglodytes	97.32	0.00e+00	1397.00
IUUC-Pan-092727	Papio anubis	97.32	0.00e+00	1396.00
IUUC-Psi-093068	Pelodiscus sinensis	91.68	0.00e+00	1314.00
IUUC-Pma-094371	Petromyzon marinus	79.43	0.00e+00	976.00
IUUC-Ppa-095209	Physcomitrella patens	30.04	1.00e-20	94.40
IUUC-Pfo-096355	Poecilia formosa	77.89	0.00e+00	899.00
IUUC-Pab-097795	Pongo abelii	98.65	0.00e+00	1077.00
IUUC-Pop-099153	Populus trichocarpa	31.12	8.00e-35	142.00
IUUC-Pva-103111	Pteropus vampyrus	96.97	0.00e+00	1348.00
IUUC-Sha-107240	Sarcophilus harrisii	95.63	0.00e+00	1366.00
IUUC-Sit-109883	Setaria italica	25.00	2.00e-17	84.30
IUUC-Sar-113739	Sorex araneus	97.15	0.00e+00	1105.00
IUUC-Sbi-114612	Sorghum bicolor	29.24	3.00e-33	137.00
IUUC-Ssc-115542	Sus scrofa	97.12	0.00e+00	933.00
IUUC-Tgu-116703	Taeniopygia guttata	91.26	0.00e+00	1318.00
IUUC-Tru-117551	Takifugu rubripes	66.20	0.00e+00	914.00
IUUC-Tsy-118944	Tarsius syrichta	91.63	0.00e+00	1283.00
IUUC-Tni-120665	Tetraodon nigroviridis	76.94	0.00e+00	873.00
IUUC-Tur-126089	Triticum urartu	32.49	1.00e-38	155.00
IUUC-Ttr-128501	Tursiops truncatus	97.25	0.00e+00	1361.00
IUUC-Vpa-130295	Vicugna pacos	88.73	0.00e+00	1211.00
IUUC-Xtr-132607	Xenopus tropicalis	85.67	0.00e+00	1212.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence