iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089555

Ensembl Protein ID

ENSOARP00000009621.1

UniProt Accession

W5PGQ5; W5PGQ5_SHEEP

Genbank Protein ID

ENSOARP00000009621

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01069096

Gene Name

TRIM72

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000008958.1	ENSOART00000009760.1	ENSOARP00000009621.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	8.70e-07	29.1	10	76
E3 activity/RING/RING	8.00e-08	32.9	14	57

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwl...asggk.tcPvtrqplteedlvPnltlrrliq 66
           +e+ Cp+ l+l++ Pv++++G+++ r+++ +     a++g+  cP +++p++++ l  nl l rl++
   Q: 10   QELSCPLCLQLFNAPVTAECGHSFCRACLSRVAgepAEDGTvLCPSCQAPTRPQALSTNLQLARLVE 76
           7899***************************776654444489****************99988765 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++Cl+ f   p++  CgH f++ Cl ++      + ++ +CP C+
   Q: 14   CPLCLQLFNA-PVTAECGHSFCRACLSRV-AGEPAEDGTVLCPSCQ 57
           ********99.999***************.5555899********7 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MSAAPGLLHQ ELSCPLCLQL FNAPVTAECG HSFCRACLSR VAGEPAEDGT VLCPSCQAPT 60
RPQALSTNLQ LARLVEGLAQ VPQGHCEEHL DPLSIYCEQD RVLVCGVCAS LGSHRGHRLL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCCGCCATG TCGGCCGCGC CCGGCCTCCT GCACCAGGAG CTGTCCTGCC CGCTGTGCCT 60
GCAGCTGTTC AACGCGCCCG TAACGGCCGA GTGTGGCCAC AGCTTCTGTC GCGCCTGCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00643--zf-B_box

SMART

SM00336--BBOX
SM00184--RING

Gene Ontology

GO:0030659--C:cytoplasmic vesicle membrane
GO:0042383--C:sarcolemma
GO:0001786--F:phosphatidylserine binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007517--P:muscle organ development
GO:0003012--P:muscle system process
GO:0046627--P:negative regulation of insulin receptor signaling pathway
GO:0043569--P:negative regulation of insulin-like growth factor receptor signaling pathway
GO:0010832--P:negative regulation of myotube differentiation
GO:0001778--P:plasma membrane repair
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051260--P:protein homooligomerization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002377	Ailuropoda melanoleuca	55.74	1.00e-117	416.00
IUUC-Aca-004755	Anolis carolinensis	49.16	2.00e-110	392.00
IUUC-Bta-013476	Bos taurus	60.54	5.00e-133	467.00
IUUC-Cja-018969	Callithrix jacchus	62.60	7.00e-147	513.00
IUUC-Cfa-020155	Canis familiaris	71.75	7.00e-173	600.00
IUUC-Cpo-021646	Cavia porcellus	68.19	1.00e-161	562.00
IUUC-Csa-023855	Chlorocebus sabaeus	60.40	1.00e-95	343.00
IUUC-Dno-029142	Dasypus novemcinctus	69.79	3.00e-146	511.00
IUUC-Dor-030394	Dipodomys ordii	88.37	8.00e-62	231.00
IUUC-Ete-032801	Echinops telfairi	76.99	5.00e-41	161.00
IUUC-Eca-034378	Equus caballus	71.22	5.00e-177	613.00
IUUC-Eeu-034526	Erinaceus europaeus	64.66	9.00e-149	520.00
IUUC-Fca-036440	Felis catus	72.18	2.00e-180	624.00
IUUC-Ggo-045086	Gorilla gorilla	95.47	6.00e-148	516.00
IUUC-Hsa-046533	Homo sapiens	72.44	7.00e-169	586.00
IUUC-Itr-048959	Ictidomys tridecemlineatus	70.06	1.00e-169	589.00
IUUC-Laf-054479	Loxodonta africana	69.14	5.00e-164	570.00
IUUC-Mcc-055814	Macaca mulatta	69.25	8.00e-159	553.00
IUUC-Meu-056767	Macropus eugenii	58.14	4.00e-133	468.00
IUUC-Mmr-061616	Microcebus murinus	69.94	2.00e-170	592.00
IUUC-Mdo-062252	Monodelphis domestica	60.50	2.00e-140	492.00
IUUC-Mmu-063094	Mus musculus	68.68	2.00e-170	591.00
IUUC-Mpu-065885	Mustela putorius furo	57.32	2.00e-122	432.00
IUUC-Mlu-068150	Myotis lucifugus	63.41	5.00e-83	300.00
IUUC-Nle-069476	Nomascus leucogenys	71.22	4.00e-168	584.00
IUUC-Opr-070871	Ochotona princeps	88.04	1.00e-125	443.00
IUUC-Oan-072738	Ornithorhynchus anatinus	61.67	6.00e-139	487.00
IUUC-Ocu-074132	Oryctolagus cuniculus	70.78	2.00e-163	568.00
IUUC-Olu-087666	Ostreococcus lucimarinus	39.19	7.00e-11	62.00
IUUC-Oga-088268	Otolemur garnettii	44.56	3.00e-71	262.00
IUUC-Ptr-090792	Pan troglodytes	72.44	7.00e-169	586.00
IUUC-Pan-092897	Papio anubis	70.96	3.00e-168	584.00
IUUC-Pab-098716	Pongo abelii	71.17	9.00e-169	586.00
IUUC-Pca-100618	Procavia capensis	92.28	9.00e-120	423.00
IUUC-Pva-102430	Pteropus vampyrus	92.68	4.00e-120	424.00
IUUC-Rno-105665	Rattus norvegicus	69.38	2.00e-173	602.00
IUUC-Sha-106854	Sarcophilus harrisii	48.87	3.00e-105	375.00
IUUC-Sar-113028	Sorex araneus	56.71	2.00e-78	285.00
IUUC-Ssc-116124	Sus scrofa	72.41	8.00e-167	580.00
IUUC-Tbe-127273	Tupaia belangeri	91.54	5.00e-65	241.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence