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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-046942
UUCD1 version UUC-HoS-00361
Ensembl Protein ID ENSP00000238647.3
UniProt Accession Q9H1B7; Q8NDQ2; Q96JG2; Q9H3I7; I2BPL_HUMAN
Genbank Protein ID CAC10539.1; BAB47494.1; CAD38615.1; AAG43156.1
Protein Name Interferon regulatory factor 2-binding protein-like; Enhanced at puberty protein 1
Genbank Nucleotide ID AJ277365; AC007686; AL832320; AF063597
Gene Name IRF2BPL; C14orf4; EAP1; KIAA1865; My039
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000119669.4 ENST00000238647.4 ENSP00000238647.3
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
THPAHPM
DNA & RNA Element
AREsiteCircNetmiRTarBasemicroRNA
TRANSFACTargetScanRepTarSomamiR
miRcodeRAID2
Protein-protein Interaction
iRefIndexMentha
Protein 3D Structure
PDBMMDB
Disease-associated Information
GWASdbOMIM
Post-translational Modifications (PTMs)
CPLMdbPAFPhosSNPPhosphositePlus
dbPTMHPRDPhospho.ELMUniProt
BioGRID
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Reviewed
Details
Family Domain References (PMIDs)
E3 activity/Other E3 activity/Other 19690564; 17334524
Organism Homo sapiens
Functional Description
(View)

Functional Description


     May contribute to the control of female reproductive function (By similarity). May play a role in gene transcription by transactivating GNRH1 promoter and repressing PENK promoter.
 May contribute to the control of female reproductive function (By similarity). May play a role in gene transcription by transactivating GNRH1 promoter and repressing PENK promoter.
Protein Sequence
(Fasta)
MSAAQVSSSR RQSCYLCDLP RMPWAMIWDF SEPVCRGCVN YEGADRIEFV IETARQLKRA 60
HGCFQDGRSP GPPPPVGVKT VALSAKEAAA AAAAAAAAAA AAQQQQQQQQ QQQQQQQQQQ 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046942|E3,E3 activity/Other|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCGAGCCGCA GCCGGAGCAG GAGCGCCGAG ACGCGCCTCC GGAACGTAGA GTAACAATCA 60
CAACCCCACA TTCCGGGCGA GCGTGAGCAC GAGCGGGAAG GGATGCGACC CGGGCCGAGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046942|E3,E3 activity/Other|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0818--Triplet repeat expansion
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR022750--Interferon_reg_fac2-bd1_2_Znf
IPR015943--WD40/YVTN_repeat-like_dom
IPR013083--Znf_RING/FYVE/PHD
Pfam

PF11261--IRF-2BP1_2
Gene Ontology

GO:0005615--C:extracellular space
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0046872--F:metal ion binding
GO:0046543--P:development of secondary female sexual characteristics
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
KEGG hsa:64207
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000340 Aegilops tauschii 31.25 5.90e-02 32.30
IUUC-Aml-001454 Ailuropoda melanoleuca 94.88 0.00e+00 779.00
IUUC-Apl-003750 Anas platyrhynchos 98.46 2.00e-76 277.00
IUUC-Bta-013237 Bos taurus 99.14 0.00e+00 811.00
IUUC-Cja-019554 Callithrix jacchus 98.50 0.00e+00 823.00
IUUC-Cfa-020161 Canis familiaris 99.36 0.00e+00 811.00
IUUC-Cpo-021335 Cavia porcellus 98.29 0.00e+00 804.00
IUUC-Csa-023425 Chlorocebus sabaeus 99.57 0.00e+00 795.00
IUUC-Cme-027246 Cyanidioschyzon merolae 25.47 1.10e-02 35.80
IUUC-Dre-028382 Danio rerio 62.31 0.00e+00 818.00
IUUC-Dno-029037 Dasypus novemcinctus 96.67 0.00e+00 863.00
IUUC-Eca-034258 Equus caballus 97.44 0.00e+00 789.00
IUUC-Fal-036602 Ficedula albicollis 69.17 4.00e-150 525.00
IUUC-Gga-040946 Gallus gallus 87.26 0.00e+00 739.00
IUUC-Gac-041747 Gasterosteus aculeatus 63.48 1.00e-145 510.00
IUUC-Ggo-044869 Gorilla gorilla 99.79 0.00e+00 797.00
IUUC-Itr-048901 Ictidomys tridecemlineatus 99.57 0.00e+00 796.00
IUUC-Lch-050611 Latimeria chalumnae 65.86 0.00e+00 842.00
IUUC-Mcc-054685 Macaca mulatta 99.57 0.00e+00 795.00
IUUC-Mga-059852 Meleagris gallopavo 92.25 2.00e-66 244.00
IUUC-Mdo-062417 Monodelphis domestica 84.34 4.00e-106 378.00
IUUC-Mmu-063451 Mus musculus 90.56 0.00e+00 1056.00
IUUC-Mpu-066363 Mustela putorius furo 98.93 0.00e+00 808.00
IUUC-Mlu-068091 Myotis lucifugus 98.72 0.00e+00 807.00
IUUC-Ocu-073852 Oryctolagus cuniculus 95.72 0.00e+00 808.00
IUUC-Ola-087118 Oryzias latipes 75.98 4.00e-67 246.00
IUUC-Oga-089136 Otolemur garnettii 98.50 0.00e+00 781.00
IUUC-Oar-089764 Ovis aries 98.93 0.00e+00 811.00
IUUC-Ptr-091196 Pan troglodytes 99.79 0.00e+00 795.00
IUUC-Pan-091901 Papio anubis 92.08 0.00e+00 1072.00
IUUC-Psi-093708 Pelodiscus sinensis 87.85 0.00e+00 741.00
IUUC-Pab-097536 Pongo abelii 98.78 8.00e-124 437.00
IUUC-Pca-100927 Procavia capensis 93.63 4.00e-149 521.00
IUUC-Pyt-104489 Pyrenophora triticirepentis 30.34 1.50e-02 34.70
IUUC-Rno-105166 Rattus norvegicus 91.45 0.00e+00 1056.00
IUUC-Sha-107263 Sarcophilus harrisii 96.84 9.00e-99 354.00
IUUC-Ssc-115892 Sus scrofa 99.36 0.00e+00 794.00
IUUC-Tgu-117405 Taeniopygia guttata 86.65 0.00e+00 741.00
IUUC-Ttr-128446 Tursiops truncatus 99.57 0.00e+00 780.00
Created Date 25-Jun-2017

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