iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-117644

UUCD1 version

UUC-TaR-00165

Ensembl Protein ID

ENSTRUP00000009086.1

UniProt Accession

H2S9L0; H2S9L0_TAKRU

Protein Name

Uncharacterized protein

Gene Name

keap1b; keap1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000003855.1	ENSTRUT00000009140.1	ENSTRUP00000009086.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	8.50e-15	56.1	61	131
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	6.20e-10	38.2	165	195

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvv.....ggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dv+l v     + + f ahk+vLa+sS+vF+a+f+++l+e    + v i+++ p+v++ l++F Yt +++ 
   Q: 61   CDVTLRVrykdlEAVDFVAHKVVLASSSPVFRAMFTNGLKECG-MELVPIEGIHPKVMERLIEFAYTASISV 131
           89999997776569****************************9.999********************98875 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           ++N++gi +fA++ +c++L+++a+++i  +F
   Q: 165  PSNAIGIASFAEQIGCTELHQKAREYIYMNF 195
           89****************************9 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

PFLRARGGGA REEMTECLTE CKALVTPSTR NGHRVFSYTL ESHTAAAFAI MNELRLERQL 60
CDVTLRVRYK DLEAVDFVAH KVVLASSSPV FRAMFTNGLK ECGMELVPIE GIHPKVMERL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGTTCCTGA GAGCCCGAGG AGGAGGAGCA CGGGAGGAAA TGACGGAGTG CCTGACAGAG 60
TGCAAAGCGC TGGTCACGCC GTCCACGCGC AACGGCCACC GGGTCTTCAG CTACACGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR030563--KEAP1
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0008134--F:transcription factor binding
GO:0071379--P:cellular response to prostaglandin stimulus
GO:0071466--P:cellular response to xenobiotic stimulus
GO:0042994--P:cytoplasmic sequestering of transcription factor
GO:0043433--P:negative regulation of sequence-specific DNA binding transcription factor activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001377	Ailuropoda melanoleuca	77.28	0.00e+00	978.00
IUUC-Aca-005389	Anolis carolinensis	77.68	0.00e+00	967.00
IUUC-Ame-010749	Astyanax mexicanus	89.66	0.00e+00	1110.00
IUUC-Bta-013505	Bos taurus	76.95	0.00e+00	973.00
IUUC-Cja-018823	Callithrix jacchus	78.29	0.00e+00	967.00
IUUC-Cfa-021202	Canis familiaris	76.78	0.00e+00	972.00
IUUC-Cpo-021830	Cavia porcellus	76.41	0.00e+00	663.00
IUUC-Csa-023728	Chlorocebus sabaeus	78.63	0.00e+00	971.00
IUUC-Cin-025195	Ciona intestinalis	52.76	0.00e+00	644.00
IUUC-Csv-026155	Ciona savignyi	51.75	2.00e-173	602.00
IUUC-Dre-027388	Danio rerio	86.84	0.00e+00	1071.00
IUUC-Dno-029066	Dasypus novemcinctus	69.49	0.00e+00	849.00
IUUC-Dor-030674	Dipodomys ordii	77.34	0.00e+00	673.00
IUUC-Dse-031490	Dothistroma septosporum	28.09	8.00e-05	40.40
IUUC-Dme-032165	Drosophila melanogaster	49.91	7.00e-161	560.00
IUUC-Eca-034381	Equus caballus	74.96	0.00e+00	951.00
IUUC-Eeu-034791	Erinaceus europaeus	79.90	0.00e+00	677.00
IUUC-Fca-036067	Felis catus	77.28	0.00e+00	976.00
IUUC-Gmo-039691	Gadus morhua	90.44	0.00e+00	1119.00
IUUC-Gga-040266	Gallus gallus	75.30	0.00e+00	919.00
IUUC-Gac-041866	Gasterosteus aculeatus	93.12	0.00e+00	1142.00
IUUC-Ggo-044719	Gorilla gorilla	77.82	0.00e+00	976.00
IUUC-Hsa-046255	Homo sapiens	77.82	0.00e+00	976.00
IUUC-Itr-048457	Ictidomys tridecemlineatus	77.82	0.00e+00	979.00
IUUC-Lch-049646	Latimeria chalumnae	81.72	0.00e+00	1001.00
IUUC-Lpe-051276	Leersia perrieri	32.59	3.00e-39	157.00
IUUC-Loc-052022	Lepisosteus oculatus	59.97	0.00e+00	666.00
IUUC-Laf-054579	Loxodonta africana	77.48	0.00e+00	973.00
IUUC-Mcc-055315	Macaca mulatta	78.63	0.00e+00	971.00
IUUC-Meu-056288	Macropus eugenii	72.65	0.00e+00	901.00
IUUC-Mmr-061639	Microcebus murinus	76.97	0.00e+00	969.00
IUUC-Mdo-062072	Monodelphis domestica	77.61	0.00e+00	986.00
IUUC-Mmu-063622	Mus musculus	77.48	0.00e+00	969.00
IUUC-Mpu-066737	Mustela putorius furo	77.34	0.00e+00	955.00
IUUC-Mlu-068173	Myotis lucifugus	76.78	0.00e+00	972.00
IUUC-Nle-069336	Nomascus leucogenys	49.32	1.00e-145	509.00
IUUC-Opr-070432	Ochotona princeps	77.65	0.00e+00	974.00
IUUC-Ont-072160	Oreochromis niloticus	93.14	0.00e+00	1157.00
IUUC-Oan-072691	Ornithorhynchus anatinus	71.53	0.00e+00	856.00
IUUC-Ocu-073798	Oryctolagus cuniculus	76.45	0.00e+00	971.00
IUUC-Obr-076181	Oryza brachyantha	31.85	1.00e-36	149.00
IUUC-Ola-086367	Oryzias latipes	87.54	0.00e+00	1075.00
IUUC-Oga-088231	Otolemur garnettii	77.48	0.00e+00	971.00
IUUC-Oar-089227	Ovis aries	75.79	0.00e+00	951.00
IUUC-Ptr-091460	Pan troglodytes	77.82	0.00e+00	976.00
IUUC-Pan-092713	Papio anubis	78.63	0.00e+00	971.00
IUUC-Pfo-096468	Poecilia formosa	92.53	0.00e+00	1131.00
IUUC-Pab-098357	Pongo abelii	77.82	0.00e+00	977.00
IUUC-Pca-100837	Procavia capensis	76.81	0.00e+00	959.00
IUUC-Pva-103249	Pteropus vampyrus	74.79	0.00e+00	919.00
IUUC-Pyt-104601	Pyrenophora triticirepentis	32.86	2.00e-05	41.60
IUUC-Rno-106086	Rattus norvegicus	76.81	0.00e+00	956.00
IUUC-Sha-107245	Sarcophilus harrisii	77.45	0.00e+00	985.00
IUUC-Sar-112985	Sorex araneus	77.48	0.00e+00	971.00
IUUC-Ssc-115756	Sus scrofa	77.11	0.00e+00	977.00
IUUC-Tgu-116838	Taeniopygia guttata	55.79	1.00e-121	429.00
IUUC-Tni-120245	Tetraodon nigroviridis	96.23	0.00e+00	1179.00
IUUC-Tbe-127472	Tupaia belangeri	79.17	3.00e-117	415.00
IUUC-Ttr-128953	Tursiops truncatus	75.44	2.00e-150	526.00
IUUC-Vpa-130683	Vicugna pacos	76.62	0.00e+00	855.00
IUUC-Xtr-132827	Xenopus tropicalis	72.29	0.00e+00	902.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence