iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	microRNA	TRANSFAC	RepTar
RAID2
Protein-protein Interaction
IID	PINA	HINT
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	1.30e-11	45.8	33	150

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmelees.................................................... 37
           +Dv+l  +g++f++hk+vLa++S++F++lf+++ + +                                                    
   Q: 33   CDVTLTAQGQQFHCHKAVLASCSQYFRSLFSSHPPLGggvggqdglgapkdqqqqqqpqqqppqqqqpppqeepgtpssspddklltsp 121
           9*********************************9777*************************************************99 PP
   S: 38   ksklmveikdvqpevfrallkFlYtgkld 66
           +  +  ++++ +   +r +l++lYt  ++
   Q: 122  RAINNLVLQGCSSIGLRLVLEYLYTANVT 150
           7799999999***************9876 PP

Organism

Mus musculus

Protein Sequence
(Fasta)

MSRSGDRTST FDPSHSDNLL HGLNLLWRKQ LFCDVTLTAQ GQQFHCHKAV LASCSQYFRS 60
LFSSHPPLGG GVGGQDGLGA PKDQQQQQQP QQQPPQQQQP PPQEEPGTPS SSPDDKLLTS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTCACTGAG CCCCAGGCCC AAGGATAATG ATGTGTTGTT TCTTGGTAGC ATAATTTGTC 60
ACACGTACAT TTTTTCTTCT TCTTCTCTTG CAGAAAGCTC TGCTCCCTCT CTCTCTCTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0256--Endoplasmic reticulum
KW-0880--Kelch repeat
KW-0472--Membrane
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030584--KLHL14
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0016235--C:aggresome
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0005789--C:endoplasmic reticulum membrane
GO:0043005--C:neuron projection
GO:0043025--C:neuronal cell body
GO:0016567--P:protein ubiquitination

KEGG

mmu:225266

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001196	Ailuropoda melanoleuca	96.65	2.00e-177	614.00
IUUC-Bta-012869	Bos taurus	97.14	0.00e+00	1185.00
IUUC-Cja-018731	Callithrix jacchus	96.67	0.00e+00	1189.00
IUUC-Cfa-020355	Canis familiaris	98.41	0.00e+00	1194.00
IUUC-Cpo-021612	Cavia porcellus	97.62	0.00e+00	1172.00
IUUC-Csa-023993	Chlorocebus sabaeus	97.78	0.00e+00	1167.00
IUUC-Dre-027629	Danio rerio	86.67	0.00e+00	1077.00
IUUC-Dno-029185	Dasypus novemcinctus	98.89	0.00e+00	1196.00
IUUC-Fca-036303	Felis catus	98.25	0.00e+00	1187.00
IUUC-Fal-037175	Ficedula albicollis	93.17	0.00e+00	1148.00
IUUC-Gmo-038807	Gadus morhua	85.74	0.00e+00	1060.00
IUUC-Gga-040750	Gallus gallus	92.73	0.00e+00	1139.00
IUUC-Gac-041372	Gasterosteus aculeatus	84.92	0.00e+00	1064.00
IUUC-Ggo-044702	Gorilla gorilla	94.46	0.00e+00	1157.00
IUUC-Hsa-046282	Homo sapiens	96.98	0.00e+00	1167.00
IUUC-Lch-049564	Latimeria chalumnae	90.81	0.00e+00	1144.00
IUUC-Loc-051831	Lepisosteus oculatus	90.00	0.00e+00	1131.00
IUUC-Laf-054353	Loxodonta africana	97.46	0.00e+00	1192.00
IUUC-Mcc-055080	Macaca mulatta	96.94	2.00e-171	595.00
IUUC-Meu-056733	Macropus eugenii	86.30	0.00e+00	818.00
IUUC-Mmr-061263	Microcebus murinus	98.10	0.00e+00	1169.00
IUUC-Mdo-061930	Monodelphis domestica	89.20	0.00e+00	1059.00
IUUC-Mpu-066871	Mustela putorius furo	98.89	0.00e+00	1194.00
IUUC-Mlu-067725	Myotis lucifugus	81.75	0.00e+00	904.00
IUUC-Nle-069427	Nomascus leucogenys	98.89	0.00e+00	1171.00
IUUC-Ont-072429	Oreochromis niloticus	86.83	0.00e+00	1088.00
IUUC-Ocu-074635	Oryctolagus cuniculus	97.15	0.00e+00	1189.00
IUUC-Ola-086870	Oryzias latipes	88.11	0.00e+00	1089.00
IUUC-Oga-088397	Otolemur garnettii	98.89	0.00e+00	1197.00
IUUC-Oar-089280	Ovis aries	99.41	0.00e+00	1021.00
IUUC-Ptr-091356	Pan troglodytes	91.90	0.00e+00	1082.00
IUUC-Pan-092718	Papio anubis	97.78	0.00e+00	1167.00
IUUC-Psi-093970	Pelodiscus sinensis	91.80	0.00e+00	1084.00
IUUC-Pfo-096550	Poecilia formosa	86.85	0.00e+00	1085.00
IUUC-Pab-097802	Pongo abelii	97.14	0.00e+00	1158.00
IUUC-Pca-101125	Procavia capensis	93.33	0.00e+00	1112.00
IUUC-Pva-102888	Pteropus vampyrus	98.12	0.00e+00	1097.00
IUUC-Rno-105007	Rattus norvegicus	99.68	0.00e+00	1200.00
IUUC-Sar-113671	Sorex araneus	96.04	0.00e+00	1154.00
IUUC-Ssc-116060	Sus scrofa	99.52	0.00e+00	1198.00
IUUC-Tgu-116795	Taeniopygia guttata	85.42	0.00e+00	1016.00
IUUC-Tru-118216	Takifugu rubripes	87.96	0.00e+00	1110.00
IUUC-Tsy-118816	Tarsius syrichta	96.33	0.00e+00	634.00
IUUC-Tni-120281	Tetraodon nigroviridis	79.84	0.00e+00	956.00
IUUC-Tbe-128057	Tupaia belangeri	93.98	0.00e+00	1116.00
IUUC-Ttr-128618	Tursiops truncatus	84.60	0.00e+00	1023.00
IUUC-Vpa-130468	Vicugna pacos	97.58	0.00e+00	731.00
IUUC-Xtr-132753	Xenopus tropicalis	88.92	0.00e+00	1101.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence