iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066273

Ensembl Protein ID

ENSMPUP00000014750.1

UniProt Accession

M3YTU0; M3YTU0_MUSPF

Genbank Protein ID

ENSMPUP00000014750

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01021486

Gene Name

RFFL

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000014861.1	ENSMPUT00000014985.1	ENSMPUP00000014750.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	91.74	0.00e+00	694.00	IUUC-Hsa-045798

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

FSPSSLAPDF IMWATCCNWF CLDGQPEEAP PAQGARTQAY SNPGYSSFPS PTGSEPSCKA 60
CGAHFANMAR KQTCLDCKKN FCMTCSSQVG NGPRLCLLCQ RVRATAFQRE ELMKMKVKDL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCTCCCCTT CCTCCCTCGC ACCAGATTTT ATCATGTGGG CAACCTGCTG CAACTGGTTC 60
TGCTTGGATG GACAGCCTGA GGAGGCCCCA CCGGCACAGG GAGCCAGGAC ACAGGCCTAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR003034--SAP_dom
IPR011011--Znf_FYVE_PHD
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0010008--C:endosome membrane
GO:0005886--C:plasma membrane
GO:0002947--C:tumor necrosis factor receptor superfamily complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:2001271--P:negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis
GO:1902042--P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1901797--P:negative regulation of signal transduction by p53 class mediator
GO:0010804--P:negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001630	Ailuropoda melanoleuca	94.65	0.00e+00	680.00
IUUC-Apl-004124	Anas platyrhynchos	65.75	3.00e-121	427.00
IUUC-Ame-011616	Astyanax mexicanus	59.18	3.00e-106	378.00
IUUC-Bta-012374	Bos taurus	86.96	0.00e+00	643.00
IUUC-Cja-019780	Callithrix jacchus	90.11	0.00e+00	660.00
IUUC-Cfa-021252	Canis familiaris	94.54	0.00e+00	664.00
IUUC-Cpo-022047	Cavia porcellus	88.47	0.00e+00	653.00
IUUC-Csa-023161	Chlorocebus sabaeus	91.18	0.00e+00	691.00
IUUC-Cho-024316	Choloepus hoffmanni	90.43	9.00e-156	542.00
IUUC-Dre-028596	Danio rerio	55.49	1.00e-110	392.00
IUUC-Dno-029333	Dasypus novemcinctus	92.29	0.00e+00	667.00
IUUC-Ete-033163	Echinops telfairi	82.64	3.00e-165	573.00
IUUC-Eca-033994	Equus caballus	92.35	0.00e+00	676.00
IUUC-Eeu-035162	Erinaceus europaeus	85.33	8.00e-129	452.00
IUUC-Fca-036418	Felis catus	93.32	0.00e+00	722.00
IUUC-Fal-037427	Ficedula albicollis	65.67	3.00e-133	468.00
IUUC-Gga-041053	Gallus gallus	67.77	3.00e-131	461.00
IUUC-Ggo-045436	Gorilla gorilla	91.74	0.00e+00	694.00
IUUC-Hsa-045798	Homo sapiens	91.74	0.00e+00	694.00
IUUC-Itr-048077	Ictidomys tridecemlineatus	90.11	0.00e+00	649.00
IUUC-Lch-050639	Latimeria chalumnae	61.71	3.00e-124	437.00
IUUC-Laf-053355	Loxodonta africana	88.04	6.00e-180	622.00
IUUC-Mcc-055222	Macaca mulatta	90.91	0.00e+00	652.00
IUUC-Meu-056692	Macropus eugenii	75.76	7.00e-155	539.00
IUUC-Mga-059298	Meleagris gallopavo	67.40	1.00e-131	462.00
IUUC-Mmr-061792	Microcebus murinus	89.81	0.00e+00	648.00
IUUC-Mdo-062986	Monodelphis domestica	77.93	2.00e-163	568.00
IUUC-Mmu-063356	Mus musculus	87.98	0.00e+00	643.00
IUUC-Mlu-066953	Myotis lucifugus	92.90	0.00e+00	694.00
IUUC-Nle-070075	Nomascus leucogenys	91.53	0.00e+00	703.00
IUUC-Opr-070838	Ochotona princeps	89.53	0.00e+00	638.00
IUUC-Ont-071967	Oreochromis niloticus	72.03	4.00e-54	204.00
IUUC-Ocu-074807	Oryctolagus cuniculus	90.71	0.00e+00	686.00
IUUC-Ola-086903	Oryzias latipes	49.06	2.00e-89	322.00
IUUC-Oga-088536	Otolemur garnettii	88.71	1.00e-178	619.00
IUUC-Oar-089838	Ovis aries	87.98	0.00e+00	631.00
IUUC-Ptr-090962	Pan troglodytes	91.46	0.00e+00	694.00
IUUC-Pan-092853	Papio anubis	90.63	0.00e+00	688.00
IUUC-Psi-093164	Pelodiscus sinensis	71.23	7.00e-127	446.00
IUUC-Pma-094104	Petromyzon marinus	44.24	2.00e-56	213.00
IUUC-Pab-098304	Pongo abelii	91.53	0.00e+00	698.00
IUUC-Pca-100316	Procavia capensis	90.63	0.00e+00	628.00
IUUC-Pva-102612	Pteropus vampyrus	77.96	9.00e-158	549.00
IUUC-Rno-105449	Rattus norvegicus	88.43	0.00e+00	638.00
IUUC-Sha-107578	Sarcophilus harrisii	78.36	2.00e-153	535.00
IUUC-Sar-113638	Sorex araneus	87.88	1.00e-179	622.00
IUUC-Ssc-116401	Sus scrofa	90.98	0.00e+00	693.00
IUUC-Tru-118765	Takifugu rubripes	48.63	7.00e-81	293.00
IUUC-Tsy-118850	Tarsius syrichta	89.11	8.00e-155	539.00
IUUC-Tbe-128086	Tupaia belangeri	82.92	3.00e-177	613.00
IUUC-Ttr-128249	Tursiops truncatus	70.80	4.00e-141	493.00
IUUC-Vpa-130816	Vicugna pacos	87.21	1.00e-40	160.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence