iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-021620

Ensembl Protein ID

ENSCPOP00000009439.2

UniProt Accession

H0VH20; H0VH20_CAVPO

Genbank Protein ID

ENSCPOP00000009439

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02048066

Gene Name

ARHGEF6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000010511.3	ENSCPOT00000010606.2	ENSCPOP00000009439.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	4.30e-14	52.2	164	218

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            v++ ++++ +n+deL+  kGd+++v     +++gW++g  +l+g+ G fP+n+v++++
   Q: 164  IVKARFNFKQTNEDELSVCKGDIIYVT--RIEEGGWWEG--TLNGRTGWFPSNYVREIK 218
           68999*********************7..9999******..8**************997 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MNPEERIVTW LISLGVLDSP KKTICDPEEF LKSSLKNGVV LCKLINRLMP GLVDKYCLEP 60
QTEANCLSNI NEFLKGCAAL QVEVFDPDDL YSGVNFSKVL TTLLAVNKAT EDQLSERPCG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAATCCAG AAGAGCGAAT CGTGACATGG CTTATATCTC TTGGCGTTTT GGATTCTCCA 60
AAAAAGACCA TCTGCGATCC AGAGGAGTTC TTGAAGTCCT CGCTGAAAAA TGGGGTAGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-1185--Reference proteome

Interpro

IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR032409--GEF_CC
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001452--SH3_domain

PROSITE

PS50021--CH
PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF16523--betaPIX_CC
PF00307--CH
PF00621--RhoGEF
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00033--CH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035556--P:intracellular signal transduction
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001631	Ailuropoda melanoleuca	78.15	0.00e+00	1226.00
IUUC-Apl-003960	Anas platyrhynchos	71.57	0.00e+00	1069.00
IUUC-Aca-004988	Anolis carolinensis	66.92	0.00e+00	982.00
IUUC-Ame-011546	Astyanax mexicanus	62.76	0.00e+00	915.00
IUUC-Bta-013527	Bos taurus	88.60	0.00e+00	1327.00
IUUC-Cja-018935	Callithrix jacchus	87.84	0.00e+00	1300.00
IUUC-Cfa-021269	Canis familiaris	87.84	0.00e+00	1301.00
IUUC-Csa-023415	Chlorocebus sabaeus	88.22	0.00e+00	1308.00
IUUC-Dre-028580	Danio rerio	61.89	0.00e+00	938.00
IUUC-Dno-029201	Dasypus novemcinctus	85.20	0.00e+00	1286.00
IUUC-Dor-030868	Dipodomys ordii	70.55	0.00e+00	964.00
IUUC-Eca-033500	Equus caballus	88.86	0.00e+00	1304.00
IUUC-Eeu-035269	Erinaceus europaeus	81.32	4.00e-164	571.00
IUUC-Fca-035683	Felis catus	87.71	0.00e+00	1283.00
IUUC-Fal-037611	Ficedula albicollis	72.09	0.00e+00	1070.00
IUUC-Gmo-038980	Gadus morhua	59.43	0.00e+00	887.00
IUUC-Gga-040940	Gallus gallus	70.23	0.00e+00	1062.00
IUUC-Gac-042203	Gasterosteus aculeatus	58.13	0.00e+00	910.00
IUUC-Ggo-044755	Gorilla gorilla	88.60	0.00e+00	1311.00
IUUC-Hsa-046210	Homo sapiens	88.09	0.00e+00	1306.00
IUUC-Lch-049517	Latimeria chalumnae	66.75	0.00e+00	997.00
IUUC-Loc-052393	Lepisosteus oculatus	63.10	0.00e+00	981.00
IUUC-Laf-054196	Loxodonta africana	87.18	0.00e+00	1253.00
IUUC-Mcc-055716	Macaca mulatta	88.22	0.00e+00	1309.00
IUUC-Meu-056285	Macropus eugenii	71.40	0.00e+00	667.00
IUUC-Mtr-058576	Medicago truncatula	43.08	5.00e-11	61.60
IUUC-Mga-060029	Meleagris gallopavo	71.45	0.00e+00	1076.00
IUUC-Mmr-060803	Microcebus murinus	88.86	0.00e+00	1313.00
IUUC-Mdo-062654	Monodelphis domestica	76.37	0.00e+00	1168.00
IUUC-Mmu-063479	Mus musculus	86.54	0.00e+00	1262.00
IUUC-Mpu-066065	Mustela putorius furo	88.08	0.00e+00	1290.00
IUUC-Mlu-068222	Myotis lucifugus	86.70	0.00e+00	1264.00
IUUC-Nle-069379	Nomascus leucogenys	88.73	0.00e+00	1313.00
IUUC-Opr-070687	Ochotona princeps	69.80	0.00e+00	776.00
IUUC-Ont-072240	Oreochromis niloticus	56.02	0.00e+00	873.00
IUUC-Oan-073067	Ornithorhynchus anatinus	76.95	0.00e+00	1169.00
IUUC-Ocu-074852	Oryctolagus cuniculus	88.09	0.00e+00	1297.00
IUUC-Oga-089048	Otolemur garnettii	82.54	0.00e+00	1118.00
IUUC-Oar-089339	Ovis aries	88.48	0.00e+00	1319.00
IUUC-Pan-092666	Papio anubis	86.21	0.00e+00	1258.00
IUUC-Psi-093116	Pelodiscus sinensis	71.87	0.00e+00	1100.00
IUUC-Pfo-097394	Poecilia formosa	60.84	0.00e+00	895.00
IUUC-Pab-098567	Pongo abelii	88.60	0.00e+00	1312.00
IUUC-Pca-100997	Procavia capensis	75.16	0.00e+00	1032.00
IUUC-Pva-102500	Pteropus vampyrus	86.30	0.00e+00	1253.00
IUUC-Rno-104974	Rattus norvegicus	86.54	0.00e+00	1238.00
IUUC-Sar-113420	Sorex araneus	82.20	0.00e+00	1196.00
IUUC-Ssc-115679	Sus scrofa	88.95	0.00e+00	1159.00
IUUC-Tgu-117069	Taeniopygia guttata	70.68	0.00e+00	1056.00
IUUC-Tsy-119243	Tarsius syrichta	78.86	0.00e+00	874.00
IUUC-Tni-120584	Tetraodon nigroviridis	58.82	0.00e+00	883.00
IUUC-Tbe-127994	Tupaia belangeri	72.22	0.00e+00	1048.00
IUUC-Ttr-128839	Tursiops truncatus	87.96	0.00e+00	1274.00
IUUC-Vpa-130144	Vicugna pacos	80.49	0.00e+00	1125.00
IUUC-Xtr-132624	Xenopus tropicalis	67.57	0.00e+00	1023.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence