iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-092979

Ensembl Protein ID

ENSPSIP00000005023.1

UniProt Accession

K7FAG3; K7FAG3_PELSI

Genbank Protein ID

ENSPSIP00000005023

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01087339

Gene Name

KLHL21

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000004691.1	ENSPSIT00000005052.1	ENSPSIP00000005023.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.10e-18	66.5	34	96
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	4.50e-06	26.0	133	162

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkl 65
           Dv++v gg ef ah++vLaa+S +F+a+f + l+es+  ++v +++v+pe++  ll+F Ytg++
   Q: 34   DVTVVAGGCEFGAHRAVLAAASGYFRAMFGGSLRESR-AERVRLHGVDPECLALLLDFAYTGRV 96
           9************************************.************************97 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkh 30
           + N+l++ +fA+++ cp L+ aa++f+l+h
   Q: 133  PANALDMQDFAEAFACPALAAAAHRFVLRH 162
           57***************************9 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

HIMEPSPGGG GESAHAVALL RGLSALRSER SLLDVTVVAG GCEFGAHRAV LAAASGYFRA 60
MFGGSLRESR AERVRLHGVD PECLALLLDF AYTGRVGRLG PDIAERLLRA ADLLQFPAVK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGAGACTCT GCAGAGTAAC CCTGCGAGTG TCGCTCCTGC ACTTGACACG CCAGACTCTT 60
GGCTTTCTTG CCGCAGCCTG TCTGTGACCG TAACCTAGCG CCTGGCACCT ATTTCCCAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005827--C:polar microtubule
GO:0004842--F:ubiquitin-protein transferase activity
GO:0035853--P:chromosome passenger complex localization to spindle midzone
GO:0032465--P:regulation of cytokinesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001782	Ailuropoda melanoleuca	74.35	0.00e+00	761.00
IUUC-Apl-003189	Anas platyrhynchos	91.93	6.00e-164	569.00
IUUC-Ame-011774	Astyanax mexicanus	63.05	1.00e-115	408.00
IUUC-Bta-012367	Bos taurus	80.82	0.00e+00	910.00
IUUC-Cja-019501	Callithrix jacchus	78.60	0.00e+00	842.00
IUUC-Cfa-020550	Canis familiaris	80.85	0.00e+00	912.00
IUUC-Cpo-022072	Cavia porcellus	82.65	0.00e+00	899.00
IUUC-Csa-023364	Chlorocebus sabaeus	84.17	0.00e+00	857.00
IUUC-Cin-025253	Ciona intestinalis	41.77	7.00e-133	467.00
IUUC-Csv-025871	Ciona savignyi	41.70	1.00e-135	476.00
IUUC-Dre-028694	Danio rerio	69.84	0.00e+00	803.00
IUUC-Dno-029082	Dasypus novemcinctus	81.93	0.00e+00	809.00
IUUC-Dor-030680	Dipodomys ordii	81.13	0.00e+00	910.00
IUUC-Ete-032315	Echinops telfairi	83.27	0.00e+00	807.00
IUUC-Eca-033570	Equus caballus	82.62	1.00e-179	621.00
IUUC-Eeu-035067	Erinaceus europaeus	81.57	4.00e-128	451.00
IUUC-Fca-035663	Felis catus	76.37	8.00e-106	375.00
IUUC-Fal-037103	Ficedula albicollis	92.27	0.00e+00	1003.00
IUUC-Gmo-039420	Gadus morhua	65.88	0.00e+00	779.00
IUUC-Ggr-039934	Gaeumannomyces graminis	32.18	3.00e-08	52.80
IUUC-Gga-040161	Gallus gallus	92.04	0.00e+00	998.00
IUUC-Gac-041755	Gasterosteus aculeatus	69.09	0.00e+00	800.00
IUUC-Ggo-044899	Gorilla gorilla	82.57	0.00e+00	915.00
IUUC-Hsa-045834	Homo sapiens	82.69	0.00e+00	913.00
IUUC-Itr-048413	Ictidomys tridecemlineatus	82.43	0.00e+00	913.00
IUUC-Lch-050338	Latimeria chalumnae	67.00	0.00e+00	816.00
IUUC-Loc-051780	Lepisosteus oculatus	69.52	0.00e+00	805.00
IUUC-Laf-053725	Loxodonta africana	83.58	0.00e+00	707.00
IUUC-Mcc-055032	Macaca mulatta	82.99	0.00e+00	781.00
IUUC-Meu-056661	Macropus eugenii	89.56	0.00e+00	726.00
IUUC-Mga-059821	Meleagris gallopavo	90.66	1.00e-144	504.00
IUUC-Mdo-062095	Monodelphis domestica	82.79	0.00e+00	782.00
IUUC-Mmu-063138	Mus musculus	83.27	0.00e+00	922.00
IUUC-Mpu-066386	Mustela putorius furo	81.99	3.00e-163	566.00
IUUC-Mlu-067807	Myotis lucifugus	86.65	0.00e+00	630.00
IUUC-Nle-069181	Nomascus leucogenys	81.08	0.00e+00	897.00
IUUC-Opr-070658	Ochotona princeps	81.03	0.00e+00	942.00
IUUC-Ont-072209	Oreochromis niloticus	69.64	0.00e+00	795.00
IUUC-Oan-072861	Ornithorhynchus anatinus	88.15	2.00e-113	400.00
IUUC-Ocu-074631	Oryctolagus cuniculus	74.26	0.00e+00	783.00
IUUC-Ola-087553	Oryzias latipes	67.86	0.00e+00	778.00
IUUC-Oga-088782	Otolemur garnettii	80.99	0.00e+00	914.00
IUUC-Oar-089634	Ovis aries	80.65	0.00e+00	910.00
IUUC-Ptr-091259	Pan troglodytes	85.34	0.00e+00	737.00
IUUC-Pan-091734	Papio anubis	82.75	0.00e+00	917.00
IUUC-Pma-094459	Petromyzon marinus	51.03	2.00e-116	412.00
IUUC-Pno-094945	Phaeosphaeria nodorum	35.29	2.00e-06	45.40
IUUC-Pfo-097446	Poecilia formosa	69.11	0.00e+00	790.00
IUUC-Pab-098765	Pongo abelii	82.12	0.00e+00	916.00
IUUC-Pva-102730	Pteropus vampyrus	77.70	0.00e+00	862.00
IUUC-Pyt-104491	Pyrenophora triticirepentis	28.74	8.00e-06	43.90
IUUC-Rno-104972	Rattus norvegicus	84.30	0.00e+00	914.00
IUUC-Ssc-115869	Sus scrofa	82.69	0.00e+00	784.00
IUUC-Tgu-116562	Taeniopygia guttata	92.02	0.00e+00	1050.00
IUUC-Tru-118490	Takifugu rubripes	67.07	0.00e+00	781.00
IUUC-Tni-119898	Tetraodon nigroviridis	65.51	0.00e+00	750.00
IUUC-Ttr-128976	Tursiops truncatus	81.67	8.00e-126	443.00
IUUC-Xtr-132876	Xenopus tropicalis	72.16	0.00e+00	843.00
IUUC-Xma-133540	Xiphophorus maculatus	68.93	0.00e+00	788.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence