iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-005077

UUCD1 version

UUC-AnC-01009

Ensembl Protein ID

ENSACAP00000009257.2

UniProt Accession

H9GF73; H9GF73_ANOCA

Protein Name

Uncharacterized protein

Gene Name

USP20

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000009302.3	ENSACAT00000009450.3	ENSACAP00000009257.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	8.30e-79	265.1	1	520

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 23   pelrelllekkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkk. 109
           p+l++++le     +    ++++k +l+ks+qkl++e+w k++ ++v p++l + +k ++++f+gy+qqD+qEfl++l+dql+eelk+ 
   Q: 1    PPLTQFFLE-----CGGLVRTDKKPALCKSYQKLVSEVWhKKRPSYVVPSSLSHGIKLVNPSFRGYAQQDTQEFLRCLMDQLHEELKEp 84
           577888888.....8889999******************99999******************************************885 PP
   S: 110  .......eknkpkeeeeeedkselsde.............................................................. 129
                   + ++ ++           +                                                              
   Q: 85   vaaevrdLEASEADD-----------Kregdrspsedeflscdsgssdrgegdgqagkaggtgmpeaelliqdeagrgisekerlkdrk 162
           544433322222222...........2333455666779************************************************** PP
   S: 130  ......................................................................................... 129
                                                                                                    
   Q: 163  fscshqrshseqvdedadvdtsvetgtegraspdilqpptprpaspartpekkntnpflplcqdcqpltsldgvvvvvvtkpgfssmrl 251
           ***********************************************************************************995555 PP
   S: 130  .............aeekkkkknkslisdlFqgqlk.................sqik.clecdnvssreepfldlslpvpgkeetkke.. 185
                                           ++                    i  ++ c +vs++ e+f+dlslp+pgke+ +k+  
   Q: 252  spgmatsmiqtlfF-----------------STTVmsvprylcvlifqdfcrFVIPpVPCCWEVSTTVETFQDLSLPIPGKEDLAKLhs 323
           55555555544443.................44444444444444444442144435789**********************99888** PP
   S: 186  .................................................slqdcLesftkeeelegenkyycekckkkqeaekklklk. 224
                                                            +l+dcL++f++++el+g+n+y+ce+ckk+++ + ++ +  
   Q: 324  aiyqnvpaktgscagdnyaasqgwiafiveyirrfvvscipswfwgpvvTLEDCLAAFFAADELKGDNMYSCERCKKLRNGSVRHCVPl 412
           ********************************************************************************988888862 PP
   S: 225  klPevLilhLkRfsfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdD 311
            l+++L++hLkRf  ++e + + ki+++v+fple Ldl+pf+++++ +q   ++Y+L++v++H+G+++sGHY+ay++n  +g+W++fdD
   Q: 413  LLSQILCIHLKRF--RHEVMYSFKISSHVSFPLEgLDLRPFLAKESASQ--VTTYDLLSVICHHGTAGSGHYIAYCQNvINGQWYEFDD 497
           68***********..9999*************************99888..9**************************78999****** PP
   S: 312  skVtevkeeevleetgstaYvlfYkr 337
           ++Vtev+e+ v++   ++aYvlfY++
   Q: 498  QYVTEVHETVVQN---AEAYVLFYRK 520
           *************...********98 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

PPLTQFFLEC GGLVRTDKKP ALCKSYQKLV SEVWHKKRPS YVVPSSLSHG IKLVNPSFRG 60
YAQQDTQEFL RCLMDQLHEE LKEPVAAEVR DLEASEADDK REGDRSPSED EFLSCDSGSS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCCCGCTCA CACAGTTCTT CCTCGAATGC GGAGGCCTGG TGCGCACAGA CAAGAAGCCG 60
GCGCTCTGCA AAAGTTACCA GAAGCTGGTT TCGGAAGTCT GGCACAAGAA GCGGTGAGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF00443--UCH

SMART

SM00695--DUSP

Gene Ontology

GO:0005813--C:centrosome
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination
GO:0008277--P:regulation of G-protein coupled receptor protein signaling pathway
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002209	Ailuropoda melanoleuca	75.59	0.00e+00	1105.00
IUUC-Apl-003351	Anas platyrhynchos	81.08	0.00e+00	1214.00
IUUC-Ame-011777	Astyanax mexicanus	69.83	0.00e+00	985.00
IUUC-Bta-013063	Bos taurus	74.80	0.00e+00	1112.00
IUUC-Cja-019868	Callithrix jacchus	76.12	0.00e+00	1137.00
IUUC-Cfa-020761	Canis familiaris	75.07	0.00e+00	1117.00
IUUC-Csa-024251	Chlorocebus sabaeus	76.75	0.00e+00	1146.00
IUUC-Cho-024483	Choloepus hoffmanni	90.14	1.00e-115	410.00
IUUC-Dre-028061	Danio rerio	66.00	0.00e+00	867.00
IUUC-Dno-029423	Dasypus novemcinctus	75.43	0.00e+00	1118.00
IUUC-Dor-030877	Dipodomys ordii	74.46	0.00e+00	860.00
IUUC-Ete-032802	Echinops telfairi	86.22	1.00e-95	343.00
IUUC-Eca-034283	Equus caballus	74.41	0.00e+00	1099.00
IUUC-Fca-036357	Felis catus	77.18	0.00e+00	1105.00
IUUC-Fal-037411	Ficedula albicollis	80.69	0.00e+00	1191.00
IUUC-Gga-041101	Gallus gallus	79.95	0.00e+00	1194.00
IUUC-Ggo-045600	Gorilla gorilla	75.59	0.00e+00	1099.00
IUUC-Hsa-045825	Homo sapiens	76.09	0.00e+00	1115.00
IUUC-Itr-048549	Ictidomys tridecemlineatus	69.22	0.00e+00	999.00
IUUC-Lch-050002	Latimeria chalumnae	69.69	0.00e+00	1000.00
IUUC-Loc-052574	Lepisosteus oculatus	73.52	0.00e+00	1043.00
IUUC-Laf-054428	Loxodonta africana	76.97	0.00e+00	1124.00
IUUC-Mcc-055736	Macaca mulatta	76.62	0.00e+00	1144.00
IUUC-Mga-059781	Meleagris gallopavo	79.84	0.00e+00	1191.00
IUUC-Mmr-061328	Microcebus murinus	88.18	0.00e+00	845.00
IUUC-Mdo-063048	Monodelphis domestica	76.19	0.00e+00	1095.00
IUUC-Mmu-064079	Mus musculus	74.84	0.00e+00	1092.00
IUUC-Mpu-066616	Mustela putorius furo	77.08	0.00e+00	1172.00
IUUC-Mlu-067294	Myotis lucifugus	75.73	0.00e+00	1084.00
IUUC-Nle-070015	Nomascus leucogenys	76.22	0.00e+00	1101.00
IUUC-Opr-070328	Ochotona princeps	76.06	0.00e+00	1133.00
IUUC-Ont-071464	Oreochromis niloticus	70.74	0.00e+00	973.00
IUUC-Oan-073259	Ornithorhynchus anatinus	87.97	0.00e+00	730.00
IUUC-Ocu-074630	Oryctolagus cuniculus	72.99	0.00e+00	1061.00
IUUC-Ola-087240	Oryzias latipes	70.86	0.00e+00	961.00
IUUC-Oga-088761	Otolemur garnettii	74.37	0.00e+00	1111.00
IUUC-Oar-089490	Ovis aries	72.21	0.00e+00	999.00
IUUC-Ptr-091662	Pan troglodytes	76.22	0.00e+00	1116.00
IUUC-Pan-092199	Papio anubis	76.42	0.00e+00	1132.00
IUUC-Psi-093726	Pelodiscus sinensis	79.87	0.00e+00	1187.00
IUUC-Pfo-096522	Poecilia formosa	66.50	0.00e+00	677.00
IUUC-Pab-098632	Pongo abelii	75.13	0.00e+00	1116.00
IUUC-Pca-100614	Procavia capensis	89.06	0.00e+00	746.00
IUUC-Rno-105215	Rattus norvegicus	75.07	0.00e+00	1101.00
IUUC-Sha-106601	Sarcophilus harrisii	75.50	0.00e+00	1061.00
IUUC-Ssc-115533	Sus scrofa	74.93	0.00e+00	1098.00
IUUC-Tgu-117364	Taeniopygia guttata	80.47	0.00e+00	1188.00
IUUC-Tru-117770	Takifugu rubripes	68.74	0.00e+00	972.00
IUUC-Tni-120001	Tetraodon nigroviridis	68.79	0.00e+00	967.00
IUUC-Ttr-128732	Tursiops truncatus	75.59	0.00e+00	1112.00
IUUC-Xtr-132157	Xenopus tropicalis	70.95	0.00e+00	983.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence