iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-073963

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02009022

Gene Name

BIRC2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000013890.2	ENSOCUT00000013891.2	ENSOCUP00000011948.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	91.12	0.00e+00	1061.00	IUUC-Hsa-045769

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MEDSTILSTW TNDNKQKMKY DFSCELYRMS TYSAFPNGVP VSERSLARAG FYYTGVNDKV 60
KCFCCGLMLD NWKQGDNPIE KHKQLYPSCS FIQNLVSASL DSTIKNTSPV RSSFAHSLSP 120

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Nucleotide Sequence
(Fasta)

ATGGAAGACA GCACCATCTT GTCAACTTGG ACAAATGACA ACAAACAAAA AATGAAGTAT 60
GACTTCTCTT GCGAACTCTA CAGAATGTCT ACCTACTCAG CTTTCCCCAA CGGTGTTCCT 120

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Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR028795--C-IAP1
IPR001315--CARD
IPR011029--DEATH-like_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01282--BIR_REPEAT_1
PS50143--BIR_REPEAT_2
PS50209--CARD
PS50089--ZF_RING_2

Pfam

PF00653--BIR
PF00619--CARD

SMART

SM00238--BIR
SM00114--CARD
SM00184--RING

Gene Ontology

GO:0035631--C:CD40 receptor complex
GO:0005737--C:cytoplasm
GO:0009898--C:cytoplasmic side of plasma membrane
GO:0005634--C:nucleus
GO:0003713--F:transcription coactivator activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0071356--P:cellular response to tumor necrosis factor
GO:0070266--P:necroptotic process
GO:0043066--P:negative regulation of apoptotic process
GO:1902443--P:negative regulation of ripoptosome assembly involved in necroptotic process
GO:0001890--P:placenta development
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:1902524--P:positive regulation of protein K48-linked ubiquitination
GO:1902523--P:positive regulation of protein K63-linked ubiquitination
GO:1902527--P:positive regulation of protein monoubiquitination
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0051726--P:regulation of cell cycle
GO:0045595--P:regulation of cell differentiation
GO:0050727--P:regulation of inflammatory response
GO:1901222--P:regulation of NIK/NF-kappaB signaling
GO:2000377--P:regulation of reactive oxygen species metabolic process
GO:0034121--P:regulation of toll-like receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002369	Ailuropoda melanoleuca	87.50	0.00e+00	1019.00
IUUC-Ang-009667	Aspergillus niger	31.06	5.00e-12	66.60
IUUC-Bta-012450	Bos taurus	86.80	0.00e+00	928.00
IUUC-Cel-018418	Caenorhabditis elegans	42.37	1.00e-09	57.40
IUUC-Cja-018895	Callithrix jacchus	90.30	0.00e+00	1030.00
IUUC-Cfa-020419	Canis familiaris	87.46	0.00e+00	1018.00
IUUC-Cpo-022048	Cavia porcellus	88.94	0.00e+00	1029.00
IUUC-Cho-024277	Choloepus hoffmanni	86.12	0.00e+00	979.00
IUUC-Cin-025521	Ciona intestinalis	30.14	3.00e-71	262.00
IUUC-Cne-027029	Cryptococcus neoformans	32.54	3.00e-13	70.10
IUUC-Dor-030796	Dipodomys ordii	72.03	1.00e-94	340.00
IUUC-Eca-033393	Equus caballus	91.49	0.00e+00	1061.00
IUUC-Eeu-035114	Erinaceus europaeus	86.10	0.00e+00	981.00
IUUC-Fca-036034	Felis catus	85.45	0.00e+00	981.00
IUUC-Gmo-038477	Gadus morhua	56.08	2.00e-174	605.00
IUUC-Gac-041467	Gasterosteus aculeatus	56.85	3.00e-177	615.00
IUUC-Ggo-044857	Gorilla gorilla	90.79	0.00e+00	1043.00
IUUC-Hsa-045769	Homo sapiens	91.12	0.00e+00	1046.00
IUUC-Itr-048441	Ictidomys tridecemlineatus	89.82	0.00e+00	1046.00
IUUC-Kpa-049324	Komagataella pastoris	30.41	3.00e-12	68.20
IUUC-Laf-053449	Loxodonta africana	85.33	0.00e+00	999.00
IUUC-Mdo-062352	Monodelphis domestica	78.09	0.00e+00	901.00
IUUC-Mmu-064340	Mus musculus	83.31	0.00e+00	968.00
IUUC-Mpu-065890	Mustela putorius furo	86.14	0.00e+00	945.00
IUUC-Mlu-068077	Myotis lucifugus	89.17	0.00e+00	1048.00
IUUC-Nle-070081	Nomascus leucogenys	90.28	0.00e+00	1048.00
IUUC-Opr-070561	Ochotona princeps	88.44	0.00e+00	991.00
IUUC-Ogu-078452	Oryza glumaepatula	45.45	4.00e-07	48.90
IUUC-Ome-081435	Oryza meridionalis	43.48	1.00e-06	47.00
IUUC-Oni-082044	Oryza nivara	41.82	2.00e-09	57.40
IUUC-Opu-084085	Oryza punctata	39.58	2.00e-06	46.60
IUUC-Oru-085060	Oryza rufipogon	44.19	1.00e-06	47.80
IUUC-Oga-087976	Otolemur garnettii	90.79	0.00e+00	1040.00
IUUC-Oar-090097	Ovis aries	87.73	0.00e+00	1024.00
IUUC-Ptr-091137	Pan troglodytes	91.12	0.00e+00	1046.00
IUUC-Pan-092673	Papio anubis	91.96	0.00e+00	1055.00
IUUC-Pab-098734	Pongo abelii	91.46	0.00e+00	1049.00
IUUC-Pca-100708	Procavia capensis	72.49	2.00e-174	605.00
IUUC-Pva-102788	Pteropus vampyrus	90.13	0.00e+00	1036.00
IUUC-Rno-105026	Rattus norvegicus	80.90	0.00e+00	949.00
IUUC-Ssc-115804	Sus scrofa	87.02	0.00e+00	999.00
IUUC-Tsy-118958	Tarsius syrichta	62.98	0.00e+00	640.00
IUUC-Tbe-127523	Tupaia belangeri	89.61	0.00e+00	1041.00
IUUC-Ttr-128954	Tursiops truncatus	87.65	0.00e+00	1006.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence