iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033489

Ensembl Protein ID

ENSECAP00000019623.1

UniProt Accession

F6Z2A3; F6Z2A3_HORSE

Protein Name

Uncharacterized protein

Gene Name

TRIM24

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000021957.1	ENSECAT00000023677.1	ENSECAP00000019623.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.30e-09	38.2	706	750

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           ++C+vC++gge    l++CekC ++fH  C+ ++   ++p+ e wiC+ Cr
   Q: 706  DWCAVCQNGGE----LLCCEKCPKVFHLSCHVPT-LANFPSGE-WICTFCR 750
           79*********....*******************.*******8.******8 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

VGVIRCPVCS QECAERHIID NFFVKDTTEV PSSTVEKSNQ VCTSCEDNAE ANGFCVECVE 60
WLCKTCIRAH QRVKFTKDHT VRQKEEVSPE AVGVTSQRPV FCPFHKKEQL KLYCETCDKL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCAGTTGGA GTCATTCGAT GTCCAGTTTG CAGCCAAGAA TGTGCAGAGA GACACATCAT 60
AGATAATTTT TTTGTGAAGG ACACTACTGA GGTTCCCAGC AGTACAGTAG AAAAGTCTAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003649--Bbox_C
IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR019786--Zinc_finger_PHD-type_CS
IPR000315--Znf_B-box
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS50119--ZF_BBOX
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00439--Bromodomain
PF00628--PHD
PF00643--zf-B_box

PRINTS

PR00503--BROMODOMAIN

SMART

SM00502--BBC
SM00336--BBOX
SM00297--BROMO
SM00249--PHD

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005719--C:nuclear euchromatin
GO:0005654--C:nucleoplasm
GO:0005726--C:perichromatin fibrils
GO:0003682--F:chromatin binding
GO:0034056--F:estrogen response element binding
GO:0004672--F:protein kinase activity
GO:0043565--F:sequence-specific DNA binding
GO:0003713--F:transcription coactivator activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0055074--P:calcium ion homeostasis
GO:0071391--P:cellular response to estrogen stimulus
GO:0008285--P:negative regulation of cell proliferation
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0046777--P:protein autophosphorylation
GO:0030163--P:protein catabolic process
GO:0042981--P:regulation of apoptotic process
GO:0031647--P:regulation of protein stability
GO:1901796--P:regulation of signal transduction by p53 class mediator
GO:0070562--P:regulation of vitamin D receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001838	Ailuropoda melanoleuca	98.71	0.00e+00	1602.00
IUUC-Apl-003697	Anas platyrhynchos	81.35	0.00e+00	1300.00
IUUC-Bta-013282	Bos taurus	97.32	0.00e+00	1587.00
IUUC-Cja-018920	Callithrix jacchus	97.20	0.00e+00	1621.00
IUUC-Cfa-020984	Canis familiaris	98.60	0.00e+00	1609.00
IUUC-Cpo-022035	Cavia porcellus	96.12	0.00e+00	1608.00
IUUC-Csa-024208	Chlorocebus sabaeus	97.95	0.00e+00	1620.00
IUUC-Cho-024413	Choloepus hoffmanni	65.50	7.00e-163	568.00
IUUC-Dno-029145	Dasypus novemcinctus	97.63	0.00e+00	1632.00
IUUC-Dor-030396	Dipodomys ordii	94.72	0.00e+00	1230.00
IUUC-Ete-032414	Echinops telfairi	88.25	0.00e+00	924.00
IUUC-Eeu-034654	Erinaceus europaeus	96.26	0.00e+00	778.00
IUUC-Fca-035844	Felis catus	94.74	0.00e+00	1484.00
IUUC-Fal-036735	Ficedula albicollis	81.01	0.00e+00	1320.00
IUUC-Gga-041124	Gallus gallus	81.03	0.00e+00	1290.00
IUUC-Ggo-044542	Gorilla gorilla	98.06	0.00e+00	1621.00
IUUC-Hsa-046785	Homo sapiens	97.95	0.00e+00	1620.00
IUUC-Itr-048262	Ictidomys tridecemlineatus	97.52	0.00e+00	1603.00
IUUC-Laf-054279	Loxodonta africana	95.48	0.00e+00	1580.00
IUUC-Mcc-055668	Macaca mulatta	98.06	0.00e+00	1622.00
IUUC-Meu-056195	Macropus eugenii	78.06	0.00e+00	802.00
IUUC-Mga-059272	Meleagris gallopavo	80.92	0.00e+00	1290.00
IUUC-Mmr-060936	Microcebus murinus	96.66	0.00e+00	1598.00
IUUC-Mdo-062848	Monodelphis domestica	90.69	0.00e+00	1481.00
IUUC-Mmu-063598	Mus musculus	95.05	0.00e+00	1558.00
IUUC-Mpu-066272	Mustela putorius furo	98.06	0.00e+00	1596.00
IUUC-Mlu-067958	Myotis lucifugus	96.03	0.00e+00	1597.00
IUUC-Nle-069375	Nomascus leucogenys	98.06	0.00e+00	1622.00
IUUC-Opr-070836	Ochotona princeps	82.96	0.00e+00	671.00
IUUC-Oan-073393	Ornithorhynchus anatinus	81.32	0.00e+00	1026.00
IUUC-Ocu-074873	Oryctolagus cuniculus	95.61	0.00e+00	1572.00
IUUC-Oga-088692	Otolemur garnettii	96.56	0.00e+00	1576.00
IUUC-Oar-090160	Ovis aries	98.06	0.00e+00	1600.00
IUUC-Ptr-090756	Pan troglodytes	97.95	0.00e+00	1620.00
IUUC-Pan-091719	Papio anubis	97.85	0.00e+00	1617.00
IUUC-Psi-093433	Pelodiscus sinensis	82.31	0.00e+00	1351.00
IUUC-Pab-098599	Pongo abelii	96.56	0.00e+00	1591.00
IUUC-Pca-100540	Procavia capensis	88.75	0.00e+00	975.00
IUUC-Pva-102478	Pteropus vampyrus	90.85	0.00e+00	1421.00
IUUC-Rno-105478	Rattus norvegicus	78.53	0.00e+00	654.00
IUUC-Sha-106740	Sarcophilus harrisii	85.88	0.00e+00	1381.00
IUUC-Sar-113615	Sorex araneus	95.95	0.00e+00	1408.00
IUUC-Ssc-115513	Sus scrofa	97.67	7.00e-149	519.00
IUUC-Tgu-117368	Taeniopygia guttata	80.06	0.00e+00	1316.00
IUUC-Tsy-118904	Tarsius syrichta	97.52	0.00e+00	1622.00
IUUC-Tbe-127354	Tupaia belangeri	83.33	0.00e+00	717.00
IUUC-Ttr-128983	Tursiops truncatus	93.94	0.00e+00	1199.00
IUUC-Vpa-130420	Vicugna pacos	96.23	0.00e+00	1575.00
IUUC-Vvi-131561	Vitis vinifera	49.06	1.00e-12	68.90
IUUC-Xtr-132822	Xenopus tropicalis	64.38	0.00e+00	1016.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence