iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-098225

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin-conjugating enzyme E2 G2; E2 ubiquitin-conjugating enzyme G2; Ubiquitin carrier protein G2; Ubiquitin-protein ligase G2

Genbank Nucleotide ID

CR857277

Gene Name

UBE2G2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000011502.2	ENSPPYT00000013357.1	ENSPPYP00000012839.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	5.70e-50	168.8	8	157

Active Site

Position(s)	Description	Evidence
89	Glycyl thioester intermediate	{ECO:0000255\|PROSITE-ProRule:PRU00388, ECO:0000255\|PROSITE-ProRule:PRU10133}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk.. 87
           Rl+ e+k+l+ +ppegi+a+p++e++++ewe+li+Gpedt++e gvF + ++fp dYP++PPk++f+ ++fhPn+y++G+vC+sil+  
   Q: 8    RLMAEYKQLTLNPPEGIVAGPMNEENFFEWEALIMGPEDTCFEFGVFPAILSFPLDYPLSPPKMRFTCEMFHPNIYPDGRVCISILHap 96
           99************************************************************************************889 PP
   S: 88   .........eeekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvre 139
                    ++e+Wsp++sve++lls++s+l epn es++n++a+++++++re++ k++++
   Q: 97   gddpmgyesSAERWSPVQSVEKILLSVVSMLXEPNDESGANVDASKMWRDDREQFYKIAKQ 157
           9999999999**********************************************99875 PP

Organism

Pongo abelii

Functional Description
(View)

Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Involved in endoplasmic reticulum-associated degradation (ERAD).

Protein Sequence
(Fasta)

MAGTALKRLM AEYKQLTLNP PEGIVAGPMN EENFFEWEAL IMGPEDTCFE FGVFPAILSF 60
PLDYPLSPPK MRFTCEMFHP NIYPDGRVCI SILHAPGDDP MGYESSAERW SPVQSVEKIL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGGGA CGGCGCTCAA GAGGCTGATG GCCGAGTACA AACGTGAGTT CGGGGACCCG 60
GGCCGTCAGC AGCGTCCCGC GTTCCTGCTC CCGGGCCCGC GTCGTCCGGC GGGGCTGGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0007--Acetylation
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0070936--P:protein K48-linked ubiquitination
GO:0018279--P:protein N-linked glycosylation via asparagine
GO:0030433--P:ubiquitin-dependent ERAD pathway

KEGG

pon:100171538

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002172	Ailuropoda melanoleuca	91.72	7.00e-85	305.00
IUUC-Apl-003761	Anas platyrhynchos	92.59	1.00e-87	314.00
IUUC-Aca-005062	Anolis carolinensis	96.97	6.00e-92	328.00
IUUC-Ago-007853	Ashbya gossypii	62.42	3.00e-58	217.00
IUUC-Acl-008080	Aspergillus clavatus	62.05	3.00e-58	217.00
IUUC-Afl-008478	Aspergillus flavus	61.45	3.00e-57	214.00
IUUC-Afu-009051	Aspergillus fumigatus	62.05	2.00e-58	217.00
IUUC-Ani-009271	Aspergillus nidulans	60.24	6.00e-52	196.00
IUUC-Ang-009748	Aspergillus niger	62.65	3.00e-58	217.00
IUUC-Aor-010228	Aspergillus oryzae	61.45	3.00e-57	214.00
IUUC-Ate-010293	Aspergillus terreus	62.05	2.00e-58	217.00
IUUC-Ame-011698	Astyanax mexicanus	92.73	4.00e-90	322.00
IUUC-Bgr-012226	Blumeria graminis	60.37	1.00e-56	211.00
IUUC-Bta-013277	Bos taurus	98.37	3.00e-70	256.00
IUUC-Bci-013676	Botrytis cinerea	60.37	4.00e-56	209.00
IUUC-Cel-018676	Caenorhabditis elegans	76.36	7.00e-74	269.00
IUUC-Cja-019767	Callithrix jacchus	98.18	6.00e-95	338.00
IUUC-Cfa-020047	Canis familiaris	95.15	4.00e-93	332.00
IUUC-Cpo-021507	Cavia porcellus	98.79	3.00e-95	339.00
IUUC-Csa-023745	Chlorocebus sabaeus	92.68	4.00e-88	316.00
IUUC-Cho-024667	Choloepus hoffmanni	65.61	3.00e-53	200.00
IUUC-Cin-025310	Ciona intestinalis	81.21	3.00e-79	286.00
IUUC-Csv-025961	Ciona savignyi	80.61	2.00e-78	284.00
IUUC-Cgl-026553	Colletotrichum gloeosporioides	64.20	2.00e-60	224.00
IUUC-Cne-026903	Cryptococcus neoformans	56.36	8.00e-47	179.00
IUUC-Dre-027900	Danio rerio	93.33	3.00e-90	323.00
IUUC-Dno-029688	Dasypus novemcinctus	92.73	1.00e-88	317.00
IUUC-Dor-030374	Dipodomys ordii	66.01	3.00e-52	196.00
IUUC-Dse-031253	Dothistroma septosporum	63.03	2.00e-61	228.00
IUUC-Dme-031849	Drosophila melanogaster	81.21	3.00e-79	286.00
IUUC-Ete-033010	Echinops telfairi	98.79	9.00e-94	335.00
IUUC-Eca-033294	Equus caballus	94.90	2.00e-87	314.00
IUUC-Eeu-034947	Erinaceus europaeus	72.44	8.00e-48	181.00
IUUC-Fca-036442	Felis catus	94.89	2.00e-76	276.00
IUUC-Fal-037188	Ficedula albicollis	95.42	2.00e-85	307.00
IUUC-Fox-037762	Fusarium oxysporum	61.82	2.00e-59	221.00
IUUC-Fso-038181	Fusarium solani	61.21	8.00e-59	218.00
IUUC-Gmo-038663	Gadus morhua	90.30	8.00e-88	315.00
IUUC-Ggr-039808	Gaeumannomyces graminis	64.20	6.00e-61	226.00
IUUC-Gga-040355	Gallus gallus	97.58	4.00e-94	336.00
IUUC-Gac-041847	Gasterosteus aculeatus	92.73	8.00e-91	325.00
IUUC-Ggo-045202	Gorilla gorilla	99.39	1.00e-95	341.00
IUUC-Hsa-046369	Homo sapiens	99.39	1.00e-95	341.00
IUUC-Itr-048349	Ictidomys tridecemlineatus	98.18	4.00e-95	339.00
IUUC-Kpa-049317	Komagataella pastoris	63.19	1.00e-58	218.00
IUUC-Lch-049596	Latimeria chalumnae	85.45	2.00e-81	294.00
IUUC-Loc-052346	Lepisosteus oculatus	92.68	2.00e-65	240.00
IUUC-Lma-053126	Leptosphaeria maculans	68.18	2.00e-51	194.00
IUUC-Laf-054560	Loxodonta africana	92.68	2.00e-87	313.00
IUUC-Mcc-055172	Macaca mulatta	99.39	1.00e-95	341.00
IUUC-Meu-056891	Macropus eugenii	94.90	2.00e-87	313.00
IUUC-Mor-057260	Magnaporthe oryzae	62.96	7.00e-60	222.00
IUUC-Mpo-057468	Magnaporthe poae	64.81	1.00e-61	228.00
IUUC-Mla-059084	Melampsora laricipopulina	58.14	3.00e-55	207.00
IUUC-Mga-059939	Meleagris gallopavo	89.63	7.00e-86	308.00
IUUC-Mvi-060514	Microbotryum violaceum	65.45	5.00e-59	219.00
IUUC-Mmr-061029	Microcebus murinus	93.45	8.00e-88	315.00
IUUC-Mdo-061820	Monodelphis domestica	98.18	5.00e-95	339.00
IUUC-Mmu-063123	Mus musculus	99.39	1.00e-95	341.00
IUUC-Mpu-065866	Mustela putorius furo	87.88	2.00e-85	306.00
IUUC-Mlu-067220	Myotis lucifugus	93.75	2.00e-87	314.00
IUUC-Nfi-068395	Neosartorya fischeri	62.05	2.00e-58	217.00
IUUC-Ncr-068623	Neurospora crassa	62.58	3.00e-58	217.00
IUUC-Nle-070007	Nomascus leucogenys	99.39	1.00e-95	341.00
IUUC-Opr-071095	Ochotona princeps	100.00	7.00e-64	234.00
IUUC-Ont-071736	Oreochromis niloticus	92.73	9.00e-90	321.00
IUUC-Oan-073475	Ornithorhynchus anatinus	94.90	8.00e-87	311.00
IUUC-Ocu-074820	Oryctolagus cuniculus	95.48	3.00e-87	313.00
IUUC-Ola-087571	Oryzias latipes	92.12	2.00e-89	320.00
IUUC-Oga-087956	Otolemur garnettii	97.62	3.00e-45	172.00
IUUC-Oar-089706	Ovis aries	98.79	1.00e-95	341.00
IUUC-Ptr-090798	Pan troglodytes	99.39	1.00e-95	341.00
IUUC-Pan-091967	Papio anubis	99.39	1.00e-95	341.00
IUUC-Psi-093524	Pelodiscus sinensis	94.04	1.00e-83	301.00
IUUC-Pma-094602	Petromyzon marinus	90.65	1.00e-73	268.00
IUUC-Pno-094979	Phaeosphaeria nodorum	64.85	8.00e-63	232.00
IUUC-Pfo-097330	Poecilia formosa	93.33	1.00e-90	325.00
IUUC-Pca-101040	Procavia capensis	97.39	5.00e-87	312.00
IUUC-Pva-102507	Pteropus vampyrus	82.17	6.00e-72	262.00
IUUC-Pgr-103674	Puccinia graminis	60.23	5.00e-56	209.00
IUUC-Ptt-103840	Puccinia triticina	59.06	3.00e-55	207.00
IUUC-Pte-104389	Pyrenophora teres	66.67	3.00e-65	240.00
IUUC-Pyt-104703	Pyrenophora triticirepentis	66.06	3.00e-64	236.00
IUUC-Rno-105228	Rattus norvegicus	99.39	1.00e-95	341.00
IUUC-Sce-106233	Saccharomyces cerevisiae	62.42	6.00e-56	209.00
IUUC-Sha-107274	Sarcophilus harrisii	90.96	5.00e-88	316.00
IUUC-Sja-107937	Schizosaccharomyces japonicus	68.32	9.00e-66	242.00
IUUC-Spo-108269	Schizosaccharomyces pombe	67.70	7.00e-66	242.00
IUUC-Ssl-108636	Sclerotinia sclerotiorum	60.98	2.00e-57	214.00
IUUC-Sre-114952	Sporisorium reilianum	64.24	2.00e-57	214.00
IUUC-Ssc-115365	Sus scrofa	92.12	2.00e-87	313.00
IUUC-Tgu-116816	Taeniopygia guttata	97.58	4.00e-94	336.00
IUUC-Tru-118547	Takifugu rubripes	80.53	2.00e-50	189.00
IUUC-Tni-120278	Tetraodon nigroviridis	89.16	6.00e-86	309.00
IUUC-Tre-122131	Trichoderma reesei	62.96	2.00e-59	221.00
IUUC-Tvi-122669	Trichoderma virens	62.96	8.00e-60	222.00
IUUC-Tme-127052	Tuber melanosporum	68.10	2.00e-66	243.00
IUUC-Tbe-127792	Tupaia belangeri	99.39	1.00e-95	341.00
IUUC-Ttr-128619	Tursiops truncatus	94.96	3.00e-64	236.00
IUUC-Uma-129587	Ustilago maydis	63.64	4.00e-57	213.00
IUUC-Vda-129914	Verticillium dahliae	62.35	6.00e-59	219.00
IUUC-Xtr-132450	Xenopus tropicalis	95.76	4.00e-92	329.00
IUUC-Xma-133016	Xiphophorus maculatus	93.94	7.00e-91	325.00
IUUC-Yli-134379	Yarrowia lipolytica	71.60	2.00e-68	250.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence