iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ang-009771

Ensembl Protein ID

CAK38851

UniProt Accession

A2QJ57; A2QJ57_ASPNC

Genbank Protein ID

CAK38851.1

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AM270079

Gene Name

An04g05870

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
An04g05870	CAK38851	CAK38851

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	4.50e-118	394.0	3735	4066

Active Site

Position(s)	Description	Evidence
4035	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkk.rlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfyklll 101
           +lk+ +l+v+f gEeg+d+gGvtre+++ l++ ++np++ lf   ++d++t++pn+ sg+ n ehl +F+f+Gr++gkal++gr+ld+++s+++yk++l
   Q: 3735 ELKYgKLNVRFHGEEGVDAGGVTREWFQVLARGMFNPNYALFIPVASDRTTFHPNRLSGV-NSEHLMFFKFIGRIIGKALYEGRVLDCHFSRAVYKCIL 3832
           66755899***************************************************9.56************************************ PP
   S: 102  gkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfnev 200
           g+++s++d+e++d ++yksl +++en   di+++ ++ tf v+++ +ge ++ +L+++G+nipVt+eNkeeY+++vv+yrl  ++keq+++f +Gf+e+
   Q: 3833 GRSVSIKDMETLDLDYYKSLLWMLEN---DITDI-ITETFAVETDDFGEKQVIDLIENGRNIPVTEENKEEYIQRVVDYRLVGSVKEQLDNFLKGFHEI 3927
           ************************99...99999.999************************************************************* PP
   S: 201  iplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelk....prlfvirk.das 294
           ip +l+s+F+e+elelli+G +ei+v+d+k +t+y++ y+++sp+iqwFw+++++f++eer+++LqFvTg+s++Pl+Gf+el+     ++f i++ +++
   Q: 3928 IPSDLISIFNEQELELLISGLPEIEVDDWKVNTEYHN-YSASSPQIQWFWRAVRSFDKEERAKLLQFVTGTSKVPLNGFKELEgmngVSRFNIHRdYGN 4025
           ***********************************66.*********************************************9999666777776899 PP
   S: 295  ddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFe 334
           +drlPss+TCfn+L+LPeY+s+e+l+++L +A++ + + F+
   Q: 4026 KDRLPSSHTCFNQLDLPEYESYETLRQRLYTAMTAGsEYFG 4066
           9********************************99877776 PP

Organism

Aspergillus niger

Protein Sequence
(Fasta)

MGRIKKVASQ KHEATISPYL ADFVARATTI PVPELPSHLN TFSRIWPFPR GDLYHWINVL 60
NRFDEILASA IEKYALNNGP QTKPFGKDFL VESYVHGDSA GKPQDVDAKL AELGYGPEGD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGAGAA TTAAGAAGGT GGCGAGCCAA AAACACGAGG CTACGATCGT GAGTCCCTCT 60
TTTCCCACCC CGCGTTCCAT CTGTCACGTC TGCCAGGCTA ACTGAATTTT TCCTTCACTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR025527--DUF4414
IPR010309--E3_Ub_ligase_DUF908
IPR010314--E3_Ub_ligase_DUF913
IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF14377--DUF4414
PF06012--DUF908
PF06025--DUF913
PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000627	Aegilops tauschii	32.21	2.00e-117	417.00
IUUC-Aml-001684	Ailuropoda melanoleuca	53.19	1.00e-133	471.00
IUUC-Atr-003044	Amborella trichopoda	42.23	1.00e-138	488.00
IUUC-Apl-003729	Anas platyrhynchos	51.83	7.00e-101	358.00
IUUC-Aca-005263	Anolis carolinensis	53.66	5.00e-135	475.00
IUUC-Aly-006157	Arabidopsis lyrata	40.76	4.00e-139	489.00
IUUC-Ath-007472	Arabidopsis thaliana	43.95	8.00e-137	481.00
IUUC-Ago-008005	Ashbya gossypii	56.90	0.00e+00	746.00
IUUC-Acl-008254	Aspergillus clavatus	76.07	0.00e+00	3583.00
IUUC-Afl-008712	Aspergillus flavus	88.41	0.00e+00	1904.00
IUUC-Afu-009022	Aspergillus fumigatus	79.46	0.00e+00	5919.00
IUUC-Ani-009412	Aspergillus nidulans	72.45	0.00e+00	3755.00
IUUC-Aor-010186	Aspergillus oryzae	85.55	0.00e+00	2180.00
IUUC-Ate-010253	Aspergillus terreus	75.15	0.00e+00	3533.00
IUUC-Ame-011067	Astyanax mexicanus	52.71	1.00e-132	468.00
IUUC-Bgr-012043	Blumeria graminis	38.90	0.00e+00	1467.00
IUUC-Bta-012813	Bos taurus	53.19	1.00e-133	471.00
IUUC-Bci-013995	Botrytis cinerea	60.27	0.00e+00	1244.00
IUUC-Bdi-014884	Brachypodium distachyon	34.51	2.00e-139	490.00
IUUC-Bol-016533	Brassica oleracea	55.27	8.00e-92	328.00
IUUC-Bra-016726	Brassica rapa	43.95	1.00e-138	488.00
IUUC-Cel-018179	Caenorhabditis elegans	51.29	1.00e-130	461.00
IUUC-Cja-018741	Callithrix jacchus	53.19	5.00e-133	469.00
IUUC-Cfa-020083	Canis familiaris	53.19	1.00e-133	471.00
IUUC-Cpo-021923	Cavia porcellus	43.85	2.00e-95	344.00
IUUC-Cre-022900	Chlamydomonas reinhardtii	51.77	1.00e-132	464.00
IUUC-Csa-023853	Chlorocebus sabaeus	53.19	1.00e-133	471.00
IUUC-Cho-024718	Choloepus hoffmanni	56.27	7.00e-123	434.00
IUUC-Cin-025627	Ciona intestinalis	52.07	4.00e-133	469.00
IUUC-Csv-025872	Ciona savignyi	51.84	6.00e-130	455.00
IUUC-Cgl-026647	Colletotrichum gloeosporioides	35.57	0.00e+00	1186.00
IUUC-Cne-027095	Cryptococcus neoformans	40.68	0.00e+00	634.00
IUUC-Cme-027267	Cyanidioschyzon merolae	51.55	2.00e-120	425.00
IUUC-Dre-028525	Danio rerio	51.67	2.00e-120	427.00
IUUC-Dno-029680	Dasypus novemcinctus	53.19	1.00e-133	471.00
IUUC-Dor-030902	Dipodomys ordii	47.75	5.00e-112	399.00
IUUC-Dse-031197	Dothistroma septosporum	35.85	0.00e+00	1291.00
IUUC-Dme-032122	Drosophila melanogaster	52.24	7.00e-130	459.00
IUUC-Eca-033915	Equus caballus	52.13	3.00e-131	463.00
IUUC-Eeu-034963	Erinaceus europaeus	52.83	1.00e-131	464.00
IUUC-Fca-035824	Felis catus	53.19	1.00e-133	471.00
IUUC-Fox-037756	Fusarium oxysporum	57.07	0.00e+00	1258.00
IUUC-Fso-038464	Fusarium solani	56.88	0.00e+00	1239.00
IUUC-Gmo-039073	Gadus morhua	52.72	1.00e-133	471.00
IUUC-Ggr-039946	Gaeumannomyces graminis	56.63	0.00e+00	1198.00
IUUC-Gga-040309	Gallus gallus	57.98	2.00e-106	376.00
IUUC-Gac-042430	Gasterosteus aculeatus	52.72	1.00e-133	471.00
IUUC-Gma-042956	Glycine max	48.05	6.00e-137	481.00
IUUC-Hsa-046879	Homo sapiens	53.19	1.00e-133	471.00
IUUC-Hvu-047697	Hordeum vulgare	34.38	5.00e-140	492.00
IUUC-Itr-048430	Ictidomys tridecemlineatus	53.19	4.00e-134	471.00
IUUC-Kpa-049228	Komagataella pastoris	59.75	0.00e+00	774.00
IUUC-Lch-050252	Latimeria chalumnae	46.56	8.00e-133	468.00
IUUC-Lpe-051550	Leersia perrieri	40.72	1.00e-137	484.00
IUUC-Loc-052472	Lepisosteus oculatus	53.19	2.00e-134	474.00
IUUC-Lma-053159	Leptosphaeria maculans	42.58	0.00e+00	1664.00
IUUC-Laf-054154	Loxodonta africana	53.19	1.00e-133	471.00
IUUC-Mcc-055085	Macaca mulatta	53.19	1.00e-133	471.00
IUUC-Mor-057201	Magnaporthe oryzae	55.78	0.00e+00	1190.00
IUUC-Mpo-057597	Magnaporthe poae	71.03	0.00e+00	963.00
IUUC-Mtr-057633	Medicago truncatula	32.31	6.00e-156	545.00
IUUC-Mla-058888	Melampsora laricipopulina	57.49	4.00e-143	499.00
IUUC-Mga-059935	Meleagris gallopavo	41.42	2.00e-93	335.00
IUUC-Mvi-060320	Microbotryum violaceum	44.31	0.00e+00	738.00
IUUC-Mmr-060820	Microcebus murinus	53.19	8.00e-134	471.00
IUUC-Mdo-062930	Monodelphis domestica	53.43	2.00e-134	473.00
IUUC-Mmu-063601	Mus musculus	53.19	1.00e-133	471.00
IUUC-Mac-065229	Musa acuminata	33.28	4.00e-156	545.00
IUUC-Mpu-066653	Mustela putorius furo	53.19	1.00e-133	471.00
IUUC-Mlu-067418	Myotis lucifugus	53.19	1.00e-133	471.00
IUUC-Nfi-068278	Neosartorya fischeri	76.09	0.00e+00	3528.00
IUUC-Ncr-068813	Neurospora crassa	33.60	0.00e+00	1127.00
IUUC-Nle-069418	Nomascus leucogenys	53.19	1.00e-133	471.00
IUUC-Ont-071300	Oreochromis niloticus	52.72	1.00e-133	471.00
IUUC-Oan-073046	Ornithorhynchus anatinus	53.41	1.00e-133	471.00
IUUC-Ocu-074178	Oryctolagus cuniculus	53.19	5.00e-134	472.00
IUUC-Oba-075757	Oryza barthii	40.38	1.00e-140	494.00
IUUC-Obr-076553	Oryza brachyantha	43.13	2.00e-140	493.00
IUUC-Ogl-077520	Oryza glaberrima	40.38	2.00e-140	493.00
IUUC-Ogu-078278	Oryza glumaepatula	40.38	1.00e-140	494.00
IUUC-Oin-079767	Oryza indica	40.38	1.00e-140	494.00
IUUC-Olo-080380	Oryza longistaminata	40.14	1.00e-138	487.00
IUUC-Ome-081925	Oryza meridionalis	40.35	8.00e-139	488.00
IUUC-Oni-082619	Oryza nivara	40.38	1.00e-140	494.00
IUUC-Opu-083684	Oryza punctata	38.87	6.00e-139	488.00
IUUC-Oru-084501	Oryza rufipogon	40.38	1.00e-140	494.00
IUUC-Osa-086251	Oryza sativa	40.38	8.00e-140	489.00
IUUC-Olu-087813	Ostreococcus lucimarinus	47.91	2.00e-115	407.00
IUUC-Oga-088903	Otolemur garnettii	53.19	1.00e-133	471.00
IUUC-Oar-090210	Ovis aries	53.19	1.00e-133	471.00
IUUC-Pan-092368	Papio anubis	52.44	8.00e-121	428.00
IUUC-Pno-094871	Phaeosphaeria nodorum	41.14	0.00e+00	1619.00
IUUC-Ppa-095657	Physcomitrella patens	46.43	5.00e-132	465.00
IUUC-Pfo-096232	Poecilia formosa	52.72	1.00e-133	471.00
IUUC-Pab-098583	Pongo abelii	53.19	1.00e-133	471.00
IUUC-Pop-099468	Populus trichocarpa	32.35	7.00e-154	538.00
IUUC-Ppe-101641	Prunus persica	44.88	7.00e-138	484.00
IUUC-Pva-102116	Pteropus vampyrus	49.88	1.00e-119	425.00
IUUC-Pgr-103465	Puccinia graminis	49.00	0.00e+00	636.00
IUUC-Ptt-103813	Puccinia triticina	40.77	0.00e+00	746.00
IUUC-Pte-104018	Pyrenophora teres	43.05	0.00e+00	1737.00
IUUC-Pyt-104713	Pyrenophora triticirepentis	42.26	0.00e+00	1713.00
IUUC-Sce-106449	Saccharomyces cerevisiae	55.97	0.00e+00	728.00
IUUC-Sha-106961	Sarcophilus harrisii	46.64	1.00e-134	474.00
IUUC-Sja-107814	Schizosaccharomyces japonicus	46.57	0.00e+00	879.00
IUUC-Spo-108024	Schizosaccharomyces pombe	45.66	0.00e+00	862.00
IUUC-Smo-109428	Selaginella moellendorffii	50.70	2.00e-134	473.00
IUUC-Sit-110598	Setaria italica	35.34	4.00e-142	499.00
IUUC-Sly-111706	Solanum lycopersicum	43.36	2.00e-138	486.00
IUUC-Stu-112582	Solanum tuberosum	34.46	2.00e-56	212.00
IUUC-Sar-113291	Sorex araneus	53.37	2.00e-129	457.00
IUUC-Sbi-114042	Sorghum bicolor	38.68	5.00e-138	485.00
IUUC-Sre-114958	Sporisorium reilianum	58.55	5.00e-175	605.00
IUUC-Ssc-115754	Sus scrofa	53.19	1.00e-133	471.00
IUUC-Tru-118570	Takifugu rubripes	52.72	1.00e-133	471.00
IUUC-Tni-120836	Tetraodon nigroviridis	51.06	7.00e-128	451.00
IUUC-Tca-121479	Theobroma cacao	32.57	2.00e-153	536.00
IUUC-Tre-121909	Trichoderma reesei	57.68	0.00e+00	1216.00
IUUC-Tvi-122370	Trichoderma virens	56.46	0.00e+00	1221.00
IUUC-Tae-125214	Triticum aestivum	33.04	5.00e-137	481.00
IUUC-Tur-126774	Triticum urartu	31.07	3.00e-50	191.00
IUUC-Tme-127172	Tuber melanosporum	72.67	0.00e+00	990.00
IUUC-Ttr-129253	Tursiops truncatus	53.19	1.00e-133	471.00
IUUC-Uma-129355	Ustilago maydis	57.76	5.00e-180	622.00
IUUC-Vda-129886	Verticillium dahliae	57.13	0.00e+00	1204.00
IUUC-Vpa-130708	Vicugna pacos	53.19	4.00e-133	469.00
IUUC-Vvi-131078	Vitis vinifera	45.37	1.00e-138	487.00
IUUC-Xtr-132123	Xenopus tropicalis	51.87	1.00e-127	451.00
IUUC-Xma-133869	Xiphophorus maculatus	52.72	5.00e-134	472.00
IUUC-Yli-134657	Yarrowia lipolytica	47.82	0.00e+00	974.00
IUUC-Zma-135570	Zea mays	43.51	2.00e-141	496.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence