iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020422

Ensembl Protein ID

ENSCAFP00000037426.1

UniProt Accession

J9NW81; J9NW81_CANLF

Genbank Protein ID

ENSCAFP00000037426

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03015287

Gene Name

CHD4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000014929.5	ENSCAFT00000048002.1	ENSCAFP00000037426.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	3.10e-16	59.6	470	514

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           ++C vC++gge    l++C+ C + +H +Cl+++  +e pn e w Cp+C+
   Q: 470  EFCRVCKDGGE----LLCCDTCPSSYHIHCLNPP-LPEIPNGE-WLCPRCT 514
           58*********....*******************.*******8.******6 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

RGPQAAGRSS WANSLAGRKG MASGLGSPSP CSAGSEEEDM DALLNNSLPP PHPENEEDPE 60
EDLSEAETPK LKKKKKPKKP RDPKIPKSKR QKKERMLLCR QLGDSSGEGP EFVEEEEEVA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGACTCGGGC CAGTGTAGAG GGCCCCAGGC CGCAGGCAGG AGCAGCTGGG CCAATTCCCT 60
GGCCGGGAGC GGAAGGGGAT GGCGTCGGGC CTGGGCTCCC CGTCCCCCTG CTCCGCGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028725--CHD4
IPR012957--CHD_C2
IPR012958--CHD_N
IPR000953--Chromo/chromo_shadow_dom
IPR023780--Chromo_domain
IPR016197--Chromodomain-like
IPR002464--DNA/RNA_helicase_DEAH_CS
IPR009462--DUF1086
IPR009463--DUF1087
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR000330--SNF2_N
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50013--CHROMO_2
PS00690--DEAH_ATP_HELICASE
PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF08074--CHDCT2
PF08073--CHDNT
PF00385--Chromo
PF06461--DUF1086
PF06465--DUF1087
PF00271--Helicase_C
PF00628--PHD
PF00176--SNF2_N

SMART

SM00298--CHROMO
SM00487--DEXDc
SM01146--DUF1086
SM01147--DUF1087
SM00490--HELICc
SM00249--PHD

Gene Ontology

GO:0005813--C:centrosome
GO:0005737--C:cytoplasm
GO:0016020--C:membrane
GO:0000790--C:nuclear chromatin
GO:0016581--C:NuRD complex
GO:0032993--C:protein-DNA complex
GO:0005524--F:ATP binding
GO:0008026--F:ATP-dependent helicase activity
GO:0031492--F:nucleosomal DNA binding
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980--F:RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0008270--F:zinc ion binding
GO:0043044--P:ATP-dependent chromatin remodeling
GO:0006355--P:regulation of transcription, DNA-templated
GO:0051225--P:spindle assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001361	Ailuropoda melanoleuca	97.16	0.00e+00	2999.00
IUUC-Apl-004175	Anas platyrhynchos	92.14	0.00e+00	2728.00
IUUC-Aca-004774	Anolis carolinensis	88.46	0.00e+00	2778.00
IUUC-Bta-013220	Bos taurus	99.01	0.00e+00	2977.00
IUUC-Cel-018683	Caenorhabditis elegans	57.61	0.00e+00	1275.00
IUUC-Cja-019510	Callithrix jacchus	92.42	0.00e+00	2673.00
IUUC-Cpo-021704	Cavia porcellus	98.65	0.00e+00	2918.00
IUUC-Csa-023625	Chlorocebus sabaeus	99.27	0.00e+00	2988.00
IUUC-Cho-024361	Choloepus hoffmanni	91.06	0.00e+00	1455.00
IUUC-Dno-029656	Dasypus novemcinctus	98.90	0.00e+00	2959.00
IUUC-Dor-030354	Dipodomys ordii	96.14	0.00e+00	1887.00
IUUC-Eca-034112	Equus caballus	99.48	0.00e+00	3003.00
IUUC-Fca-036056	Felis catus	99.84	0.00e+00	3001.00
IUUC-Fal-037312	Ficedula albicollis	96.29	0.00e+00	2318.00
IUUC-Gga-040216	Gallus gallus	92.33	0.00e+00	2811.00
IUUC-Gac-042478	Gasterosteus aculeatus	77.59	0.00e+00	2016.00
IUUC-Ggo-044428	Gorilla gorilla	89.92	0.00e+00	2646.00
IUUC-Hsa-045908	Homo sapiens	97.47	0.00e+00	2981.00
IUUC-Itr-048002	Ictidomys tridecemlineatus	99.42	0.00e+00	2971.00
IUUC-Lch-049948	Latimeria chalumnae	78.13	0.00e+00	1902.00
IUUC-Loc-052144	Lepisosteus oculatus	85.23	0.00e+00	2108.00
IUUC-Mcc-055773	Macaca mulatta	97.53	0.00e+00	2986.00
IUUC-Mga-059633	Meleagris gallopavo	92.46	0.00e+00	2816.00
IUUC-Mmr-060886	Microcebus murinus	97.78	0.00e+00	2988.00
IUUC-Mdo-062872	Monodelphis domestica	95.84	0.00e+00	2643.00
IUUC-Mmu-063672	Mus musculus	99.50	0.00e+00	2437.00
IUUC-Mpu-066692	Mustela putorius furo	99.79	0.00e+00	3001.00
IUUC-Mlu-067785	Myotis lucifugus	99.22	0.00e+00	2988.00
IUUC-Nle-070039	Nomascus leucogenys	97.60	0.00e+00	2915.00
IUUC-Ont-072418	Oreochromis niloticus	82.61	0.00e+00	2114.00
IUUC-Ocu-074177	Oryctolagus cuniculus	96.64	0.00e+00	2966.00
IUUC-Ola-086880	Oryzias latipes	81.36	0.00e+00	2160.00
IUUC-Oga-088970	Otolemur garnettii	97.94	0.00e+00	3000.00
IUUC-Oar-090422	Ovis aries	98.96	0.00e+00	2884.00
IUUC-Pan-092441	Papio anubis	99.37	0.00e+00	2994.00
IUUC-Psi-093530	Pelodiscus sinensis	90.26	0.00e+00	2774.00
IUUC-Ppa-095213	Physcomitrella patens	42.11	0.00e+00	726.00
IUUC-Pfo-097530	Poecilia formosa	82.84	0.00e+00	2098.00
IUUC-Pab-097959	Pongo abelii	96.94	0.00e+00	2883.00
IUUC-Pva-103186	Pteropus vampyrus	97.86	0.00e+00	2914.00
IUUC-Rno-105692	Rattus norvegicus	97.44	0.00e+00	2889.00
IUUC-Ssc-115295	Sus scrofa	99.42	0.00e+00	2969.00
IUUC-Tgu-117484	Taeniopygia guttata	90.04	0.00e+00	2810.00
IUUC-Tsy-119261	Tarsius syrichta	87.36	0.00e+00	2069.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence