iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049774

Ensembl Protein ID

ENSLACP00000018381.2

UniProt Accession

H3B910; H3B910_LATCH

Genbank Protein ID

ENSLACP00000018381

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01065007

Gene Name

RNF19A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000016189.2	ENSLACT00000018514.2	ENSLACP00000018381.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	4.40e-52	177.5	106	306

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpekleeseikellveeelykryekllleevveadaalkw 90
           C++Cll++s+++++ +++C+h+ C +Cl+qyl+++i+e++ ++iscp  ec+e++++++i+ +l ++ l+++ye+++l++++ ad++++w
   Q: 106  CPLCLLRHSKDRFPEIMTCHHRSCVDCLRQYLRIEISESR-VNISCP--ECSERFNPHDIRMILNDDVLMEKYEEFMLRRWLVADPDCRW 192
           ****************************************.9*****..89*************************************** PP
   S: 91   cpapdCslvvllekea..eklevecekcgkefCveCkeewHeglsCkelkeklakteeek.......eeaeskelleanskkCpkCkvyi 171
           cpapdC ++v++  +a  +kl++ +e+cg+efC++Ck+ wH++++C+++++++a++ + +       + ++++ ++++++k+Cp+C +yi
   Q: 193  CPAPDCGYAVIAFGCAscPKLSCGREGCGTEFCYHCKQLWHPNQTCDAARQQRAQSLRLRtirsssiSYSQESGAAADDIKPCPRCAAYI 282
           *************999889************************************99998999**9999999****************** PP
   S: 172  ek..negCnhmtCakCkaefCwlC 193
           +k  +++CnhmtCa C++efCwlC
   Q: 283  IKmnDGSCNHMTCAVCGCEFCWLC 306
           *997889***************** PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MSAVNMSLHR QMGSEHDLQS SASSVSLPSV KKAPKKRRLS LGSLFRKKKD PKRKSRDLNG 60
GVDGIASIES IHSEMCNDKN SMFPTCTTSE SVPASNSKQT GDFMECPLCL LRHSKDRFPE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGTCACCAAA ATGTGTAGTC CTGGCACCTA TTTAATTGTG ACTAGAGTGC GCTTTACGTC 60
AGTGGAATGT GTGCACTGGG ATCGTTTGGG TGTGTATGCG TGAGAGAGAC AGAGTGAACG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF01485--IBR

SMART

SM00647--IBR
SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding

KEGG

lcm:102345215

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001958	Ailuropoda melanoleuca	84.40	0.00e+00	1154.00
IUUC-Apl-003427	Anas platyrhynchos	86.72	0.00e+00	1127.00
IUUC-Aca-004252	Anolis carolinensis	84.80	0.00e+00	1095.00
IUUC-Ame-011434	Astyanax mexicanus	75.30	0.00e+00	897.00
IUUC-Bta-013558	Bos taurus	84.40	0.00e+00	1155.00
IUUC-Cja-019070	Callithrix jacchus	84.50	0.00e+00	1153.00
IUUC-Cfa-020286	Canis familiaris	84.28	0.00e+00	1152.00
IUUC-Cpo-022015	Cavia porcellus	84.22	0.00e+00	1141.00
IUUC-Csa-023975	Chlorocebus sabaeus	84.59	0.00e+00	1136.00
IUUC-Cho-024442	Choloepus hoffmanni	70.52	0.00e+00	931.00
IUUC-Dre-028422	Danio rerio	74.06	0.00e+00	900.00
IUUC-Dno-029018	Dasypus novemcinctus	84.17	0.00e+00	1123.00
IUUC-Dor-030548	Dipodomys ordii	76.52	2.00e-149	523.00
IUUC-Eca-034249	Equus caballus	84.52	0.00e+00	1158.00
IUUC-Eeu-035298	Erinaceus europaeus	92.01	0.00e+00	757.00
IUUC-Fca-035912	Felis catus	84.40	0.00e+00	1154.00
IUUC-Fal-037488	Ficedula albicollis	84.75	0.00e+00	1086.00
IUUC-Gmo-038893	Gadus morhua	82.22	0.00e+00	803.00
IUUC-Gga-040380	Gallus gallus	86.63	0.00e+00	1110.00
IUUC-Gac-041421	Gasterosteus aculeatus	76.27	0.00e+00	892.00
IUUC-Ggo-044893	Gorilla gorilla	84.62	0.00e+00	1157.00
IUUC-Hsa-046876	Homo sapiens	84.50	0.00e+00	1156.00
IUUC-Itr-048257	Ictidomys tridecemlineatus	84.28	0.00e+00	1152.00
IUUC-Loc-052040	Lepisosteus oculatus	80.24	0.00e+00	1018.00
IUUC-Laf-053874	Loxodonta africana	85.01	0.00e+00	1144.00
IUUC-Mcc-054817	Macaca mulatta	86.73	2.00e-84	305.00
IUUC-Mla-059062	Melampsora laricipopulina	24.59	2.00e-10	60.50
IUUC-Mga-060175	Meleagris gallopavo	86.72	0.00e+00	1127.00
IUUC-Mmr-060800	Microcebus murinus	84.52	0.00e+00	1155.00
IUUC-Mdo-061827	Monodelphis domestica	83.09	0.00e+00	1055.00
IUUC-Mmu-064134	Mus musculus	82.11	0.00e+00	1087.00
IUUC-Mpu-066076	Mustela putorius furo	84.03	0.00e+00	1150.00
IUUC-Mlu-068218	Myotis lucifugus	84.00	0.00e+00	1103.00
IUUC-Nle-069707	Nomascus leucogenys	91.26	0.00e+00	976.00
IUUC-Opr-070977	Ochotona princeps	83.66	0.00e+00	1155.00
IUUC-Ont-072373	Oreochromis niloticus	76.55	0.00e+00	942.00
IUUC-Oan-073376	Ornithorhynchus anatinus	95.83	2.00e-156	545.00
IUUC-Ocu-074878	Oryctolagus cuniculus	83.66	0.00e+00	1130.00
IUUC-Ola-086472	Oryzias latipes	78.01	0.00e+00	926.00
IUUC-Oga-088377	Otolemur garnettii	84.64	0.00e+00	1151.00
IUUC-Oar-089540	Ovis aries	83.91	0.00e+00	1147.00
IUUC-Ptr-090613	Pan troglodytes	84.50	0.00e+00	1156.00
IUUC-Pan-092879	Papio anubis	84.71	0.00e+00	1133.00
IUUC-Psi-093201	Pelodiscus sinensis	86.22	0.00e+00	1092.00
IUUC-Pma-094620	Petromyzon marinus	71.59	0.00e+00	802.00
IUUC-Pfo-096615	Poecilia formosa	80.15	0.00e+00	885.00
IUUC-Pca-100625	Procavia capensis	83.66	0.00e+00	1125.00
IUUC-Pva-103110	Pteropus vampyrus	79.22	0.00e+00	936.00
IUUC-Rno-105998	Rattus norvegicus	81.74	0.00e+00	1088.00
IUUC-Sha-107523	Sarcophilus harrisii	83.46	0.00e+00	1046.00
IUUC-Sar-113089	Sorex araneus	80.65	0.00e+00	818.00
IUUC-Ssc-115471	Sus scrofa	84.03	0.00e+00	1121.00
IUUC-Tgu-117080	Taeniopygia guttata	85.24	0.00e+00	1119.00
IUUC-Tru-117547	Takifugu rubripes	79.47	0.00e+00	885.00
IUUC-Tsy-119143	Tarsius syrichta	83.54	0.00e+00	1135.00
IUUC-Tni-119693	Tetraodon nigroviridis	75.31	0.00e+00	891.00
IUUC-Ttr-129175	Tursiops truncatus	83.66	0.00e+00	1139.00
IUUC-Vpa-130594	Vicugna pacos	77.63	0.00e+00	1061.00
IUUC-Xtr-132579	Xenopus tropicalis	86.03	0.00e+00	1120.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence