iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062519

UUCD1 version

UUC-MoD-00915

Ensembl Protein ID

ENSMODP00000014676.2

UniProt Accession

F7FT50; F7FT50_MONDO

Protein Name

Uncharacterized protein

Gene Name

POC1A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000011717.3	ENSMODT00000014947.2	ENSMODP00000014676.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.80e-56	184.4	153	191
UBD/Beta-Prp	4.80e-75	252.7	109	316

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           H ++v+c +f +d +l+vs+sdD+t+k+WD ++  +++s
   Q: 153  HINWVRCAKFsPDgRLIVSASDDKTVKLWDKTSRECVHS 191
           999********999******************9999886 PP

UBD/Beta-Prp

   S: 49   sgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghd 137
             h+++v++v fs+dg+ lvt+s+D+t+kvw +   k + ++++h + v++ +fsp+g  +vs+s+d+t+++wd  +++c++  + +h 
   Q: 109  RAHTGTVRSVHFSSDGQSLVTASDDKTLKVWTVHRQKFLFSFTQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSRECVH-SFCEHG 196
           67********************************************************************************.****** PP
   S: 138  gvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvk 226
           g+vn+v +hp+g +++++++D+tv+lWd++t++ll++ +  h   v+ lsf+++g++l+++s+d+t+k+ dl +g+ ++tl+gh  + +
   Q: 197  GFVNYVDFHPSGTCIAAAGTDNTVKLWDIRTNRLLQHYQL-HSAVVNALSFHPSGNYLITASNDSTLKILDLMEGRLLYTLHGHLGPAT 284
           ***************************************8.************************************************ PP
   S: 227  svrfspnderlvsgssDgsiriW..dlrsgdl 256
           +v+fs+ +e+++sg+ D+++ +W  + +  d+
   Q: 285  CVAFSRSGELFASGGTDEQVMVWksNFDVTDY 316
           ***********************884433333 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MALFKDSIRS YPGRKEDPSL ERNFRGHKDA VTSVDFSANR KQLVSGSMDA CLMIWHMKPH 60
MRAYRFVGHK DAVMCVNFSP SGHLVASGSR DKTVRIWVPN LKGESTVFRA HTGTVRSVHF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCTTGGAAC CATTACATAG TATTGATTCT ATAATGGACA GTGTTAAAAA AAATTAACAT 60
TTGGTGGACT AAAGAGAAAA CATGGCAGTT CCAGGAAAAA AAAAATTTAC TTCTGCCTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005814--C:centriole
GO:0036064--C:ciliary basal body
GO:0000922--C:spindle pole
GO:0003431--P:growth plate cartilage chondrocyte development
GO:0007052--P:mitotic spindle organization
GO:1905515--P:non-motile cilium assembly
GO:0010825--P:positive regulation of centrosome duplication
GO:0007283--P:spermatogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001513	Ailuropoda melanoleuca	77.57	3.00e-171	594.00
IUUC-Apl-003466	Anas platyrhynchos	79.30	3.00e-177	614.00
IUUC-Aca-004323	Anolis carolinensis	69.19	4.00e-167	580.00
IUUC-Bta-012484	Bos taurus	78.86	2.00e-179	621.00
IUUC-Cja-019067	Callithrix jacchus	76.84	1.00e-172	599.00
IUUC-Cfa-020439	Canis familiaris	78.32	2.00e-178	618.00
IUUC-Cpo-021403	Cavia porcellus	77.03	2.00e-176	611.00
IUUC-Cre-022724	Chlamydomonas reinhardtii	52.89	1.00e-111	396.00
IUUC-Csa-023479	Chlorocebus sabaeus	77.45	9.00e-156	542.00
IUUC-Cho-024354	Choloepus hoffmanni	76.82	6.00e-102	363.00
IUUC-Cin-025258	Ciona intestinalis	73.44	4.00e-144	504.00
IUUC-Csv-025955	Ciona savignyi	62.96	5.00e-134	470.00
IUUC-Dno-029467	Dasypus novemcinctus	72.24	2.00e-115	408.00
IUUC-Dor-030399	Dipodomys ordii	78.02	3.00e-176	611.00
IUUC-Dme-032182	Drosophila melanogaster	46.20	6.00e-81	294.00
IUUC-Eca-034425	Equus caballus	78.38	3.00e-170	591.00
IUUC-Eeu-034607	Erinaceus europaeus	66.94	5.00e-142	497.00
IUUC-Fca-035627	Felis catus	77.75	5.00e-174	603.00
IUUC-Fal-037381	Ficedula albicollis	76.34	7.00e-174	603.00
IUUC-Gmo-038489	Gadus morhua	67.66	4.00e-150	523.00
IUUC-Gga-040559	Gallus gallus	75.60	3.00e-171	594.00
IUUC-Gac-041453	Gasterosteus aculeatus	67.20	8.00e-152	530.00
IUUC-Ggo-044773	Gorilla gorilla	78.05	8.00e-172	596.00
IUUC-Hsa-045823	Homo sapiens	78.05	3.00e-171	594.00
IUUC-Itr-048560	Ictidomys tridecemlineatus	77.84	3.00e-177	614.00
IUUC-Lch-050558	Latimeria chalumnae	69.85	8.00e-170	589.00
IUUC-Loc-052836	Lepisosteus oculatus	69.53	1.00e-167	582.00
IUUC-Laf-053974	Loxodonta africana	70.16	4.00e-151	527.00
IUUC-Mcc-055494	Macaca mulatta	75.47	5.00e-167	580.00
IUUC-Meu-056646	Macropus eugenii	82.64	2.00e-140	491.00
IUUC-Mga-059295	Meleagris gallopavo	67.07	8.00e-163	566.00
IUUC-Mmr-061040	Microcebus murinus	79.40	4.00e-177	613.00
IUUC-Mmu-063759	Mus musculus	85.91	2.00e-156	545.00
IUUC-Mpu-066442	Mustela putorius furo	78.05	7.00e-173	599.00
IUUC-Mlu-068163	Myotis lucifugus	79.40	1.00e-177	615.00
IUUC-Nle-070160	Nomascus leucogenys	77.24	2.00e-170	591.00
IUUC-Opr-070192	Ochotona princeps	77.06	2.00e-158	551.00
IUUC-Ont-072539	Oreochromis niloticus	75.57	4.00e-149	521.00
IUUC-Oan-072834	Ornithorhynchus anatinus	63.28	5.00e-115	407.00
IUUC-Ocu-074624	Oryctolagus cuniculus	78.64	8.00e-164	569.00
IUUC-Ola-087268	Oryzias latipes	61.15	9.00e-145	506.00
IUUC-Oga-088964	Otolemur garnettii	78.65	9.00e-178	615.00
IUUC-Oar-090202	Ovis aries	79.19	2.00e-173	602.00
IUUC-Ptr-091164	Pan troglodytes	77.84	2.00e-171	595.00
IUUC-Pan-092805	Papio anubis	76.85	3.00e-154	538.00
IUUC-Psi-093359	Pelodiscus sinensis	85.35	1.00e-168	585.00
IUUC-Pma-094425	Petromyzon marinus	77.74	6.00e-152	530.00
IUUC-Ppa-095677	Physcomitrella patens	48.03	4.00e-86	311.00
IUUC-Pfo-096741	Poecilia formosa	72.97	2.00e-139	488.00
IUUC-Pab-098376	Pongo abelii	77.78	4.00e-176	610.00
IUUC-Pca-101122	Procavia capensis	77.51	1.00e-175	608.00
IUUC-Pva-103104	Pteropus vampyrus	74.11	9.00e-135	473.00
IUUC-Rno-105282	Rattus norvegicus	78.64	2.00e-158	551.00
IUUC-Sha-106840	Sarcophilus harrisii	86.64	2.00e-129	454.00
IUUC-Smo-109423	Selaginella moellendorffii	46.50	4.00e-83	301.00
IUUC-Ssc-115392	Sus scrofa	82.46	7.00e-166	576.00
IUUC-Tgu-117340	Taeniopygia guttata	76.55	2.00e-169	588.00
IUUC-Tru-117577	Takifugu rubripes	72.48	8.00e-136	477.00
IUUC-Tsy-119404	Tarsius syrichta	74.32	4.00e-162	563.00
IUUC-Tni-120713	Tetraodon nigroviridis	64.71	3.00e-138	484.00
IUUC-Tbe-127788	Tupaia belangeri	60.00	9.00e-116	410.00
IUUC-Ttr-128608	Tursiops truncatus	75.07	4.00e-164	570.00
IUUC-Xtr-132720	Xenopus tropicalis	78.64	1.00e-149	522.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence