iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062651

UUCD1 version

UUC-MoD-00468

Ensembl Protein ID

ENSMODP00000010672.4

UniProt Accession

F7CCW5; F7CCW5_MONDO

Protein Name

Uncharacterized protein

Gene Name

ZNRF3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000008580.4	ENSMODT00000010881.4	ENSMODP00000010672.4

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	65.55	0.00e+00	872.00	IUUC-Hsa-046484

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MGWNPWQMHP LGLCNNNDEE DLYEYGWVGV VKLEQPELDP KPCLTVLGKA KRAVQRGATA 60
VIFDVSENPD AIDQLNQGSE DPLKRPVVYV KGADALKLMN IVNKQKVARA RIQHRPPRQP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAATTGCTGG GATGGGCTGG AATCCTTGGC AGGTAAGATA ACCTCCAAGA GTCTGTTTCC 60
TCCACTGACA GTTTTTGTTT TACTTCACCT GAGAGTTATT GCTTGGAAGA AGCCCCTTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005887--C:integral component of plasma membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0060070--P:canonical Wnt signaling pathway
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:2000051--P:negative regulation of non-canonical Wnt signaling pathway
GO:0072089--P:stem cell proliferation
GO:0006511--P:ubiquitin-dependent protein catabolic process
GO:0038018--P:Wnt receptor catabolic process
GO:0060071--P:Wnt signaling pathway, planar cell polarity pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001916	Ailuropoda melanoleuca	67.86	0.00e+00	858.00
IUUC-Apl-004188	Anas platyrhynchos	64.95	0.00e+00	882.00
IUUC-Aly-005850	Arabidopsis lyrata	43.90	8.00e-16	76.30
IUUC-Ath-007372	Arabidopsis thaliana	43.90	3.00e-15	74.30
IUUC-Ame-011764	Astyanax mexicanus	62.61	0.00e+00	705.00
IUUC-Bta-012478	Bos taurus	94.09	2.00e-92	333.00
IUUC-Bol-016217	Brassica oleracea	41.46	3.00e-14	70.90
IUUC-Bra-017407	Brassica rapa	41.46	3.00e-14	70.90
IUUC-Cja-019504	Callithrix jacchus	69.60	0.00e+00	896.00
IUUC-Cfa-020048	Canis familiaris	67.19	0.00e+00	889.00
IUUC-Cpo-021725	Cavia porcellus	63.79	0.00e+00	867.00
IUUC-Csa-023586	Chlorocebus sabaeus	66.51	0.00e+00	845.00
IUUC-Cho-024867	Choloepus hoffmanni	81.11	1.00e-161	563.00
IUUC-Cin-025569	Ciona intestinalis	47.73	7.00e-56	211.00
IUUC-Csv-025869	Ciona savignyi	45.45	3.00e-50	193.00
IUUC-Dre-027553	Danio rerio	59.95	0.00e+00	761.00
IUUC-Dno-029370	Dasypus novemcinctus	65.95	0.00e+00	856.00
IUUC-Dor-030816	Dipodomys ordii	69.02	0.00e+00	814.00
IUUC-Ete-033060	Echinops telfairi	64.54	0.00e+00	657.00
IUUC-Eca-034044	Equus caballus	66.87	0.00e+00	885.00
IUUC-Eeu-034591	Erinaceus europaeus	49.68	1.00e-84	308.00
IUUC-Fca-036000	Felis catus	66.83	0.00e+00	895.00
IUUC-Fal-037147	Ficedula albicollis	64.58	0.00e+00	894.00
IUUC-Gmo-039099	Gadus morhua	51.57	2.00e-113	402.00
IUUC-Gga-041243	Gallus gallus	59.72	0.00e+00	674.00
IUUC-Gac-041340	Gasterosteus aculeatus	49.74	1.00e-107	383.00
IUUC-Gma-044387	Glycine max	36.63	9.00e-15	73.60
IUUC-Ggo-044953	Gorilla gorilla	67.11	0.00e+00	882.00
IUUC-Hsa-046484	Homo sapiens	67.23	0.00e+00	889.00
IUUC-Itr-048470	Ictidomys tridecemlineatus	69.39	0.00e+00	883.00
IUUC-Lch-050004	Latimeria chalumnae	56.98	0.00e+00	631.00
IUUC-Loc-051830	Lepisosteus oculatus	61.50	0.00e+00	746.00
IUUC-Laf-053975	Loxodonta africana	67.64	0.00e+00	919.00
IUUC-Mcc-055302	Macaca mulatta	65.90	0.00e+00	846.00
IUUC-Meu-056263	Macropus eugenii	79.09	0.00e+00	822.00
IUUC-Mtr-058744	Medicago truncatula	39.56	5.00e-14	70.50
IUUC-Mga-059706	Meleagris gallopavo	65.07	0.00e+00	912.00
IUUC-Mmr-061372	Microcebus murinus	65.23	0.00e+00	863.00
IUUC-Mmu-064339	Mus musculus	70.20	0.00e+00	879.00
IUUC-Mac-065356	Musa acuminata	40.21	1.00e-13	70.90
IUUC-Mpu-066211	Mustela putorius furo	63.46	0.00e+00	841.00
IUUC-Mlu-067058	Myotis lucifugus	66.67	0.00e+00	803.00
IUUC-Nle-069886	Nomascus leucogenys	66.71	0.00e+00	865.00
IUUC-Opr-070218	Ochotona princeps	67.78	0.00e+00	767.00
IUUC-Ont-072483	Oreochromis niloticus	58.01	0.00e+00	749.00
IUUC-Oan-073718	Ornithorhynchus anatinus	71.64	0.00e+00	819.00
IUUC-Ocu-073847	Oryctolagus cuniculus	64.50	0.00e+00	791.00
IUUC-Oba-075528	Oryza barthii	43.10	3.00e-12	66.20
IUUC-Obr-076311	Oryza brachyantha	41.03	6.00e-13	68.60
IUUC-Ogl-077034	Oryza glaberrima	53.06	3.00e-11	62.80
IUUC-Ogu-078680	Oryza glumaepatula	53.06	1.00e-11	63.90
IUUC-Oin-079182	Oryza indica	53.06	1.00e-11	63.50
IUUC-Oni-082249	Oryza nivara	53.06	1.00e-11	63.90
IUUC-Oru-084953	Oryza rufipogon	53.06	2.00e-11	63.20
IUUC-Osa-085734	Oryza sativa	53.06	2.00e-11	63.20
IUUC-Ola-087358	Oryzias latipes	62.20	0.00e+00	736.00
IUUC-Oga-088362	Otolemur garnettii	66.34	0.00e+00	872.00
IUUC-Oar-090197	Ovis aries	89.77	2.00e-92	333.00
IUUC-Ptr-091350	Pan troglodytes	67.11	0.00e+00	888.00
IUUC-Pan-091700	Papio anubis	65.94	0.00e+00	843.00
IUUC-Psi-093301	Pelodiscus sinensis	63.46	0.00e+00	848.00
IUUC-Pfo-096917	Poecilia formosa	60.86	0.00e+00	727.00
IUUC-Pab-097932	Pongo abelii	67.55	0.00e+00	899.00
IUUC-Pop-099512	Populus trichocarpa	44.74	2.00e-15	75.50
IUUC-Pca-101054	Procavia capensis	77.57	0.00e+00	771.00
IUUC-Ppe-101991	Prunus persica	43.48	3.00e-13	67.80
IUUC-Pva-102879	Pteropus vampyrus	66.03	0.00e+00	877.00
IUUC-Pgr-103476	Puccinia graminis	41.27	5.00e-10	58.50
IUUC-Sha-106507	Sarcophilus harrisii	63.70	0.00e+00	712.00
IUUC-Sit-110370	Setaria italica	52.17	1.00e-10	60.50
IUUC-Stu-112500	Solanum tuberosum	62.79	3.00e-13	68.20
IUUC-Sar-113182	Sorex araneus	85.89	7.00e-105	375.00
IUUC-Sbi-113770	Sorghum bicolor	50.91	4.00e-11	61.60
IUUC-Ssc-115966	Sus scrofa	68.70	0.00e+00	765.00
IUUC-Tgu-116864	Taeniopygia guttata	54.39	5.00e-152	531.00
IUUC-Tru-118502	Takifugu rubripes	61.34	0.00e+00	728.00
IUUC-Tsy-119210	Tarsius syrichta	68.10	0.00e+00	868.00
IUUC-Tni-120344	Tetraodon nigroviridis	53.06	7.00e-123	434.00
IUUC-Tca-120966	Theobroma cacao	48.39	5.00e-13	68.60
IUUC-Tbe-127735	Tupaia belangeri	64.76	4.00e-90	326.00
IUUC-Ttr-128714	Tursiops truncatus	59.12	0.00e+00	730.00
IUUC-Vvi-131598	Vitis vinifera	45.45	8.00e-14	70.10
IUUC-Xtr-132280	Xenopus tropicalis	59.29	0.00e+00	654.00
IUUC-Xma-134192	Xiphophorus maculatus	61.41	0.00e+00	741.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence