iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093942

Ensembl Protein ID

ENSPSIP00000016071.1

UniProt Accession

K7G710; K7G710_PELSI

Genbank Protein ID

ENSPSIP00000016071

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01049457

Gene Name

USP4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000014081.1	ENSPSIT00000016147.1	ENSPSIP00000016071.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.30e-112	375.5	289	899
ULD/UDP/UBQ/UBQ_Other	2.20e-12	46.7	129	207

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           +Gl+NlgNtC+mNS+LQcLsn+p+l+e++le +++ ++n++np ++ ge++++++ l++++w++++++v+pr+++ +++++a++fsgy+
   Q: 289  CGLSNLGNTCFMNSALQCLSNTPPLTEYFLEdRYEAEINHDNPLGMRGEIAEAYAGLIKQMWSGRHSHVAPRMFKVQVGRFAPQFSGYQ 377
           7******************************9********************************************************* PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           qqD+qE+laflld+l+e+l++ k+kp+ e+++++   ++d+     a+e++  +n+s+i+d+F+g +ks+++c++c +vs++++pf++l
   Q: 378  QQDSQELLAFLLDGLHEDLNRVKKKPYLELKDAN--GRPDSvvakeAWENHRLRNDSIIVDIFHGLFKSTLVCPKCSKVSVTFDPFCYL 464
           *****************************98888..5555455777******************************************* PP
   S: 173  slpvpgkeetkke............................................................................ 185
           +lp+p k+++++                                                                             
   Q: 465  TLPLPLKKDRSMDvsvvfadphrrptqyrvvvptmgavsdlcealsklskipagnmvvtdvynhrfhkifqmdeglshimpkdnifvye 553
           ******99998889*************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 554  vckpgvdgvesvtlsvyfrdkrlrqsgtsgavlcgqpllicvpkhkltldhlysvlleqigrylkfppakessrvcqdagicngssggc 642
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 643  eveemehqdgdeecrtkapetdscqsqgcaqdspgkegqhckkplftfslvnsygtseinsvvtegkllqlnshatlaidlephtwell 731
           ***************************************************************************************** PP
   S: 186  .........................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksreki 249
                                     l+dc+e ft+ e+l +++ +yc++ckk+q+a+kk++l++lP++L++hLkRfs++++   r k+
   Q: 732  seeqesqafdkdvsvlhsqkkktpvALKDCIELFTTMETLGEHDPWYCPNCKKHQQATKKFDLWSLPRILVVHLKRFSYNRY--WRDKL 818
           *****************************************************************************99885..567** PP
   S: 250  nkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlf 334
           ++ vefp++ L++spf+++p+ +   ++ Y+Liav +H+G ++ GHY+ay+kn+ ++ W++fdDs+V+  +e+++++   + aYvlf
   Q: 819  DTVVEFPIRdLSMSPFVCDPTAD---PYVYDLIAVSNHYGAMGVGHYTAYAKNDVNGrWYYFDDSSVSLASEDQIVT---KAAYVLF 899
           *******************9976...9**************************65555*******************...******9 PP

ULD/UDP/UBQ/UBQ_Other

   S: 5    vksldgs.eltlkvnpsdtVaeLKekiekklgip.peqqrLiyk......GkiLeddktLadyglkdgstihllekksg 75
           ++++d +  lt+ ++++d Va++ ++++++++ip + + rL+ +       ++   d t++d gl++g+++++++k+++
   Q: 129  CENSDPTnLLTCCFSKADAVATIEKEMRQLFNIPsEKETRLWSRymsnsyEQVSNLDSTVQDAGLYHGQVLLIEVKNED 207
           7888888899999*********************777*****777777766677********************99986 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MLWQVQTESC SHISLKRFPR YLIDSRWFKQ WKKYVGFDSW DMYNVGEPNL FPGPIDNSGL 60
FADPEIQILK EHLIDELDYV LVPTEAWNKL VSWYGCVDGQ QPILRKVVEY GLFVKHCKVE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTCTGGC AGGTACAAAC TGAAAGCTGC TCACACATCT CGTTGAAACG TTTCCCCAGG 60
TATTTGATTG ACAGTCGGTG GTTCAAACAG TGGAAGAAGT ATGTGGGTTT TGACAGCTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF14836--Ubiquitin_3
PF00443--UCH

SMART

SM00695--DUSP

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0031397--P:negative regulation of protein ubiquitination
GO:0016579--P:protein deubiquitination
GO:0034394--P:protein localization to cell surface
GO:0031647--P:regulation of protein stability
GO:0000244--P:spliceosomal tri-snRNP complex assembly
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

pss:102463622

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000058	Aegilops tauschii	40.12	4.00e-119	422.00
IUUC-Aml-001597	Ailuropoda melanoleuca	75.14	0.00e+00	1284.00
IUUC-Atr-002991	Amborella trichopoda	37.38	8.00e-142	497.00
IUUC-Apl-004068	Anas platyrhynchos	74.25	0.00e+00	1249.00
IUUC-Aca-004459	Anolis carolinensis	74.89	0.00e+00	1250.00
IUUC-Aly-006315	Arabidopsis lyrata	40.58	5.00e-123	435.00
IUUC-Ath-007343	Arabidopsis thaliana	36.65	2.00e-146	512.00
IUUC-Ago-007911	Ashbya gossypii	39.28	7.00e-69	256.00
IUUC-Ame-011064	Astyanax mexicanus	63.85	0.00e+00	859.00
IUUC-Bta-012929	Bos taurus	75.22	0.00e+00	1296.00
IUUC-Bdi-014523	Brachypodium distachyon	34.61	4.00e-129	455.00
IUUC-Bra-017554	Brassica rapa	41.03	2.00e-119	422.00
IUUC-Cel-018257	Caenorhabditis elegans	33.04	1.00e-91	330.00
IUUC-Cja-018798	Callithrix jacchus	73.99	0.00e+00	1264.00
IUUC-Cfa-020599	Canis familiaris	75.87	0.00e+00	1294.00
IUUC-Cpo-022144	Cavia porcellus	73.21	0.00e+00	1281.00
IUUC-Cre-022582	Chlamydomonas reinhardtii	59.31	4.00e-69	254.00
IUUC-Csa-023770	Chlorocebus sabaeus	74.28	0.00e+00	1230.00
IUUC-Cho-024595	Choloepus hoffmanni	66.98	0.00e+00	806.00
IUUC-Dno-029316	Dasypus novemcinctus	73.58	0.00e+00	1282.00
IUUC-Dse-031432	Dothistroma septosporum	40.58	7.00e-59	223.00
IUUC-Ete-032970	Echinops telfairi	69.61	0.00e+00	813.00
IUUC-Eca-034012	Equus caballus	74.75	0.00e+00	1269.00
IUUC-Fca-035373	Felis catus	73.28	0.00e+00	1268.00
IUUC-Fal-037634	Ficedula albicollis	78.70	0.00e+00	1323.00
IUUC-Gmo-038866	Gadus morhua	64.93	0.00e+00	1064.00
IUUC-Ggr-039740	Gaeumannomyces graminis	42.86	9.00e-61	229.00
IUUC-Gga-040729	Gallus gallus	75.74	0.00e+00	1294.00
IUUC-Gac-042631	Gasterosteus aculeatus	66.67	0.00e+00	1134.00
IUUC-Ggo-045337	Gorilla gorilla	73.41	0.00e+00	1149.00
IUUC-Hsa-045669	Homo sapiens	74.55	0.00e+00	1280.00
IUUC-Itr-048610	Ictidomys tridecemlineatus	74.97	0.00e+00	1287.00
IUUC-Lch-050533	Latimeria chalumnae	66.82	0.00e+00	1102.00
IUUC-Lpe-051424	Leersia perrieri	37.51	1.00e-145	510.00
IUUC-Loc-051800	Lepisosteus oculatus	64.44	0.00e+00	1187.00
IUUC-Laf-053803	Loxodonta africana	76.13	0.00e+00	1297.00
IUUC-Mcc-055556	Macaca mulatta	71.40	0.00e+00	1192.00
IUUC-Meu-056742	Macropus eugenii	68.43	0.00e+00	1107.00
IUUC-Mga-059300	Meleagris gallopavo	75.57	0.00e+00	1274.00
IUUC-Mdo-061848	Monodelphis domestica	75.17	0.00e+00	1291.00
IUUC-Mmu-063960	Mus musculus	73.59	0.00e+00	1258.00
IUUC-Mpu-066920	Mustela putorius furo	75.87	0.00e+00	1293.00
IUUC-Mlu-068088	Myotis lucifugus	74.38	0.00e+00	1268.00
IUUC-Nle-070010	Nomascus leucogenys	74.44	0.00e+00	1278.00
IUUC-Opr-070740	Ochotona princeps	74.68	0.00e+00	927.00
IUUC-Ont-072573	Oreochromis niloticus	64.90	0.00e+00	1147.00
IUUC-Oan-073363	Ornithorhynchus anatinus	71.28	0.00e+00	1249.00
IUUC-Ocu-074242	Oryctolagus cuniculus	71.00	0.00e+00	1192.00
IUUC-Obr-076902	Oryza brachyantha	37.42	1.00e-143	503.00
IUUC-Ogu-077990	Oryza glumaepatula	40.91	3.00e-122	432.00
IUUC-Oni-082303	Oryza nivara	40.91	1.00e-122	434.00
IUUC-Oru-085141	Oryza rufipogon	40.99	1.00e-125	444.00
IUUC-Ola-086553	Oryzias latipes	65.82	0.00e+00	1169.00
IUUC-Olu-087717	Ostreococcus lucimarinus	39.67	5.00e-118	418.00
IUUC-Oga-088562	Otolemur garnettii	69.73	0.00e+00	1166.00
IUUC-Oar-090439	Ovis aries	75.11	0.00e+00	1291.00
IUUC-Ptr-090801	Pan troglodytes	74.64	0.00e+00	1281.00
IUUC-Pan-092717	Papio anubis	69.97	0.00e+00	1153.00
IUUC-Pfo-097060	Poecilia formosa	63.69	0.00e+00	1131.00
IUUC-Pop-099801	Populus trichocarpa	37.96	1.00e-148	520.00
IUUC-Pca-100161	Procavia capensis	73.79	0.00e+00	864.00
IUUC-Rno-106081	Rattus norvegicus	74.32	0.00e+00	1276.00
IUUC-Sha-106937	Sarcophilus harrisii	75.00	0.00e+00	1291.00
IUUC-Spo-108291	Schizosaccharomyces pombe	43.38	1.00e-72	268.00
IUUC-Smo-109250	Selaginella moellendorffii	51.76	4.00e-72	265.00
IUUC-Sly-111746	Solanum lycopersicum	37.96	2.00e-147	516.00
IUUC-Stu-112671	Solanum tuberosum	37.43	7.00e-147	514.00
IUUC-Sar-113542	Sorex araneus	72.59	0.00e+00	1237.00
IUUC-Sbi-114031	Sorghum bicolor	40.35	1.00e-121	430.00
IUUC-Ssc-115637	Sus scrofa	75.03	0.00e+00	1283.00
IUUC-Tgu-117267	Taeniopygia guttata	76.42	0.00e+00	1311.00
IUUC-Tru-118634	Takifugu rubripes	66.89	0.00e+00	1103.00
IUUC-Tur-126478	Triticum urartu	40.00	6.00e-119	421.00
IUUC-Ttr-128778	Tursiops truncatus	74.07	0.00e+00	1267.00
IUUC-Vvi-131010	Vitis vinifera	39.44	6.00e-148	518.00
IUUC-Xtr-132305	Xenopus tropicalis	67.26	0.00e+00	1184.00
IUUC-Xma-133176	Xiphophorus maculatus	61.49	0.00e+00	1032.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence