iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gac-041856

UUCD1 version

UUC-GaA-00899

Ensembl Protein ID

ENSGACP00000022846.1

UniProt Accession

G3PZ06; G3PZ06_GASAC

Protein Name

Uncharacterized protein

Gene Name

RCBTB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000017297.1	ENSGACT00000022889.1	ENSGACP00000022846.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	3.50e-90	303.2	307	645

Active Site

Position(s)	Description	Evidence
614	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 6    kkrle.vefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknp.....ehlklFeflGrllgkalqdgrll 88
            +r++ v++vgE + d+gGv+ ++++++++el++  + l+  s+n ++++ +n+d++l np     eh   F+flG+l+g+a++++++l
   Q: 307  PSRAWkVKLVGEGADDAGGVFDDTITEMCQELETGVVDLLIPSPNATAEVGYNRDRFLFNPstcldEHVIQFRFLGILMGVAIRTKKPL 395
           466666*********************************************************************************** PP
   S: 89   dlplsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeee..LkpgGenipVtneNkeeYvk 175
           dl+l++ ++k+l+  +l+ledleevd  ++++lk+i++ ++s i+e++++ ++  ++ + ++++ ++  ++pgG++ip   +N++eYv+
   Q: 396  DLHLAPLVWKQLCCIPLTLEDLEEVDLLYVQTLKSILHIEDSGITEENFHEMIPLDSFVGQSADGKMvpIIPGGNSIPLSFSNRKEYVE 484
           *****************************************************9999887777766666******************** PP
   S: 176  lvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkaf 264
           + +eyrl+e i++qv+a+reG+++++p  llsl+t++ le+++cG++ei  e lkk  +y++ ++e+++ +qwFw++leefs+eer  f
   Q: 485  RAIEYRLHE-IDRQVAAVREGMSWIVPVPLLSLLTARHLEQMVCGMPEICCEVLKKVVRYRE-VEEQHSLVQWFWQTLEEFSNEERVLF 571
           *********.**************************************************88.************************** PP
   S: 265  LqFvTgssrlPlgGfaelkprlfvirk....dasd.drlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           ++Fv+g+srlP+ + a+++ ++f+i k      ++ d+lP+s+TCf++L+LP+Yss+ ++ e+L+yAi++++++++
   Q: 572  MRFVSGRSRLPA-NTADIS-QRFQIMKvdrrPPQPyDSLPTSQTCFFQLRLPPYSSQAVMAERLRYAINNCRSIDM 645
           ***********6.889999.6799999999845556***********************************99987 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

MVWAFGDGDY GKLGLGNSTA KSSPQKVDAL CGSGIIKVAC GTQFSVALTS DGKVFTFGQD 60
RLIGLPEGRA RNHNRPQQVP ALSGVHIQDV AVGAEHTLVL SSTGDVYTWG SNSEGQLGLG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAGAGCGGC GAGGTCTTCA GCTGGGGCGA CGGGGACTAC GGCAAGCTGG GCCACGGCAA 60
CAGCGACCGG CAGCGCCGGC CCCGGCAGAT CGAGGCGCTG CAGGGCGAGG AGGTGGTGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR009091--RCC1/BLIP-II
IPR000408--Reg_chr_condens

PROSITE

PS50237--HECT
PS50012--RCC1_3

Pfam

PF00632--HECT
PF00415--RCC1

PRINTS

PR00633--RCCNDNSATION

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cho-024567	Choloepus hoffmanni	82.88	0.00e+00	1073.00
IUUC-Ete-032598	Echinops telfairi	83.44	0.00e+00	1093.00
IUUC-Gmo-038634	Gadus morhua	90.98	0.00e+00	1207.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence