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Tag Content
iUUCD ID IUUC-Mcc-054865
Ensembl Protein ID ENSMMUP00000020299.3
UniProt Accession H9ES76; F6QA16; H9ES76_MACMU
Genbank Protein ID AFE65235.1; AFH30626.1; AFI35748.1
Protein Name E3 ubiquitin-protein ligase MYLIP
Genbank Nucleotide ID JSUE03030317; JU473822; JV045677
Gene Name MYLIP
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMMUG00000015474.3 ENSMMUT00000021700.3 ENSMMUP00000020299.3
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/RING/RING 98.88 0.00e+00 860.00 IUUC-Hsa-046869
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Macaca mulatta
Protein Sequence
(Fasta)
MLCYVTRPDA VLMEVEVEAK ANGEDCLNQV CRRLGIIEVD YFGLQFTGSK GESLWLNLRN 60
RISQQIDGLA PYRLKLRVKF FVEPHLILQE QTRHIFFLHI KEALLAGHLL CSPEQAVELS 120
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Protein Fasta Sequence


>IUUC-Mcc-054865|E3,RING|Macaca mulatta
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Nucleotide Sequence
(Fasta)
GCGGCCGCGG GGCGCAGGAC AAGGGTCCGC AGAGCTGCAG CCTTCGAGGG CCAGCCCTCT 60
CCGAGTCCGG GGCTGGGTCC CAGCCGTGAC AAGGCGGCAG CCCTGCGCAC ACCAAAGAGA 120
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Nucleotide Fasta Sequence


>IUUC-Mcc-054865|E3,RING|Macaca mulatta
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Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR019749--Band_41_domain
IPR001370--BIR_rpt
IPR000798--Ez/rad/moesin-like
IPR014352--FERM/acyl-CoA-bd_prot_3-hlx
IPR019748--FERM_central
IPR000299--FERM_domain
IPR018979--FERM_N
IPR018980--FERM_PH-like_C
IPR011993--PH_dom-like
IPR029071--Ubiquitin-rel_dom
IPR001841--Znf_RING
PROSITE

PS50057--FERM_3
PS50089--ZF_RING_2
Pfam

PF09380--FERM_C
PF00373--FERM_M
PF09379--FERM_N
PRINTS

PR00935--BAND41
PR00661--ERMFAMILY
SMART

SM00295--B41
SM01196--FERM_C
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005856--C:cytoskeleton
GO:0019898--C:extrinsic component of membrane
GO:0016874--F:ligase activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0042632--P:cholesterol homeostasis
GO:0010989--P:negative regulation of low-density lipoprotein particle clearance
GO:0007399--P:nervous system development
GO:0045732--P:positive regulation of protein catabolic process
GO:0031648--P:protein destabilization
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0032803--P:regulation of low-density lipoprotein particle receptor catabolic process
KEGG mcc:702625
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001425 Ailuropoda melanoleuca 95.43 0.00e+00 807.00
IUUC-Apl-003704 Anas platyrhynchos 90.69 0.00e+00 769.00
IUUC-Aca-004645 Anolis carolinensis 89.44 0.00e+00 774.00
IUUC-Ame-011401 Astyanax mexicanus 75.00 0.00e+00 655.00
IUUC-Bta-012752 Bos taurus 94.21 0.00e+00 708.00
IUUC-Cja-019734 Callithrix jacchus 98.43 0.00e+00 857.00
IUUC-Cfa-020145 Canis familiaris 95.53 0.00e+00 733.00
IUUC-Cpo-021436 Cavia porcellus 95.53 0.00e+00 718.00
IUUC-Csa-024248 Chlorocebus sabaeus 99.78 0.00e+00 867.00
IUUC-Cho-024528 Choloepus hoffmanni 84.27 0.00e+00 684.00
IUUC-Cin-025748 Ciona intestinalis 36.70 2.00e-47 182.00
IUUC-Csv-025837 Ciona savignyi 38.56 9.00e-91 327.00
IUUC-Dre-027847 Danio rerio 74.89 0.00e+00 663.00
IUUC-Dno-029860 Dasypus novemcinctus 95.53 0.00e+00 696.00
IUUC-Dor-030664 Dipodomys ordii 83.37 0.00e+00 709.00
IUUC-Dse-031509 Dothistroma septosporum 45.10 1.00e-09 58.90
IUUC-Dme-031990 Drosophila melanogaster 31.23 1.00e-37 151.00
IUUC-Ete-032496 Echinops telfairi 75.60 4.00e-149 520.00
IUUC-Eca-033674 Equus caballus 95.32 0.00e+00 867.00
IUUC-Eeu-035048 Erinaceus europaeus 88.09 0.00e+00 778.00
IUUC-Fca-036547 Felis catus 95.19 0.00e+00 811.00
IUUC-Fal-037504 Ficedula albicollis 91.37 0.00e+00 759.00
IUUC-Gmo-038660 Gadus morhua 74.41 3.00e-153 535.00
IUUC-Gga-040123 Gallus gallus 91.46 0.00e+00 805.00
IUUC-Gac-042073 Gasterosteus aculeatus 72.54 0.00e+00 632.00
IUUC-Ggo-045387 Gorilla gorilla 99.33 0.00e+00 863.00
IUUC-Hsa-046869 Homo sapiens 98.88 0.00e+00 866.00
IUUC-Itr-047917 Ictidomys tridecemlineatus 94.61 0.00e+00 835.00
IUUC-Lch-049990 Latimeria chalumnae 82.92 0.00e+00 780.00
IUUC-Lpe-051271 Leersia perrieri 39.62 2.00e-07 54.30
IUUC-Loc-051908 Lepisosteus oculatus 75.89 0.00e+00 675.00
IUUC-Lma-053223 Leptosphaeria maculans 50.00 8.00e-08 53.50
IUUC-Laf-053915 Loxodonta africana 95.28 0.00e+00 838.00
IUUC-Meu-056826 Macropus eugenii 85.71 8.00e-74 270.00
IUUC-Mga-059827 Meleagris gallopavo 90.70 0.00e+00 726.00
IUUC-Mmr-060734 Microcebus murinus 97.75 0.00e+00 874.00
IUUC-Mdo-062988 Monodelphis domestica 94.38 0.00e+00 855.00
IUUC-Mmu-064415 Mus musculus 95.51 0.00e+00 803.00
IUUC-Mpu-066118 Mustela putorius furo 95.53 0.00e+00 716.00
IUUC-Mlu-067131 Myotis lucifugus 95.06 0.00e+00 827.00
IUUC-Nle-070112 Nomascus leucogenys 99.33 0.00e+00 861.00
IUUC-Opr-071193 Ochotona princeps 92.94 0.00e+00 791.00
IUUC-Ont-072635 Oreochromis niloticus 74.50 0.00e+00 647.00
IUUC-Oan-073266 Ornithorhynchus anatinus 91.11 0.00e+00 761.00
IUUC-Ocu-074903 Oryctolagus cuniculus 93.93 0.00e+00 835.00
IUUC-Oba-075143 Oryza barthii 39.62 2.00e-07 54.30
IUUC-Ome-081491 Oryza meridionalis 39.62 2.00e-07 54.30
IUUC-Oni-082255 Oryza nivara 39.62 2.00e-07 54.30
IUUC-Oru-084921 Oryza rufipogon 39.62 2.00e-07 54.30
IUUC-Ola-087533 Oryzias latipes 71.82 4.00e-177 613.00
IUUC-Oga-087979 Otolemur garnettii 97.98 0.00e+00 882.00
IUUC-Oar-089747 Ovis aries 94.71 0.00e+00 783.00
IUUC-Ptr-090732 Pan troglodytes 99.10 0.00e+00 861.00
IUUC-Pan-092032 Papio anubis 99.78 0.00e+00 867.00
IUUC-Psi-093296 Pelodiscus sinensis 90.93 0.00e+00 781.00
IUUC-Pma-094351 Petromyzon marinus 50.28 2.00e-32 131.00
IUUC-Pfo-097183 Poecilia formosa 73.74 7.00e-175 606.00
IUUC-Pab-098177 Pongo abelii 99.10 0.00e+00 861.00
IUUC-Pca-100734 Procavia capensis 93.03 0.00e+00 833.00
IUUC-Ppe-101272 Prunus persica 43.10 1.00e-09 57.80
IUUC-Pva-102778 Pteropus vampyrus 96.39 0.00e+00 817.00
IUUC-Rno-106039 Rattus norvegicus 95.28 0.00e+00 835.00
IUUC-Sha-106869 Sarcophilus harrisii 93.99 0.00e+00 797.00
IUUC-Sar-113587 Sorex araneus 64.66 2.00e-146 512.00
IUUC-Ssc-116212 Sus scrofa 95.96 0.00e+00 841.00
IUUC-Tgu-116871 Taeniopygia guttata 91.13 0.00e+00 758.00
IUUC-Tru-117925 Takifugu rubripes 72.99 0.00e+00 673.00
IUUC-Tsy-118815 Tarsius syrichta 95.67 0.00e+00 793.00
IUUC-Tni-120007 Tetraodon nigroviridis 73.42 0.00e+00 640.00
IUUC-Tbe-127381 Tupaia belangeri 94.60 0.00e+00 667.00
IUUC-Ttr-129025 Tursiops truncatus 80.53 0.00e+00 642.00
IUUC-Vpa-130164 Vicugna pacos 91.10 1.00e-147 516.00
IUUC-Xtr-132800 Xenopus tropicalis 82.92 0.00e+00 743.00
Created Date 25-Jun-2017

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