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Tag Content
iUUCD ID IUUC-Psi-093832
Ensembl Protein ID ENSPSIP00000018640.1
UniProt Accession K7GEC9; K7GEC9_PELSI
Genbank Protein ID ENSPSIP00000018640
Protein Name Uncharacterized protein
Genbank Nucleotide ID AGCU01006165
Gene Name HERC3
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSPSIG00000016415.1 ENSPSIT00000018726.1 ENSPSIP00000018640.1
ENSPSIG00000016415.1 ENSPSIT00000018733.1 ENSPSIP00000018647.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/HECT 5.40e-91 305.5 727 1050
Active Site
Position(s) Description Evidence
1019 Glycyl thioester intermediate {ECO:0000256|PROSITE-ProRule:PRU00104}
Domain Profile

   E3 activity/HECT
   S: 4    dlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           dlkk l+v f gEe++d+gGvt+ef+ ll+kel np +g+f++ ++++  ++ +         + ++F+++G+++g+a+++  ++dl
   Q: 727  DLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELLNPIYGMFTFYPESNLLWFSDMCFV-----EHNWFHLIGIVCGLAIYNFTVVDL 808
           899***********************************************99777554.....579********************* PP
   S: 91   plsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklv 177
           +++ ++yk+ll++k  ledl+e+ p+  +sl++++++  +d+ee+ ++l+f++  e++g t++++L+p+G++i V ++N++e+v+++
   Q: 809  HFPLALYKKLLNVKPCLEDLKELSPTEGRSLQQLLDYPGDDVEET-FCLNFTICRESYGVTEQKKLIPEGDKIAVQKDNRQEFVDAY 894
           *************************************99888887.*******9********************************* PP
   S: 178  veyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkaf 264
           ++y++  +++e + af+ Gf +v+  ++l+lF++ el+ +i G++++++++l++ + ykg+y++++p++++Fwe++++f se++k+f
   Q: 895  LNYIFSLSVHEWYIAFSTGFLKVCGGKVLELFQPTELRAMIVGNSNYNWKELEECAVYKGDYSATHPTVRMFWETFHDFPSEKKKKF 981
           *************************************************************************************** PP
   S: 265  LqFvTgssrlPlgGfaelkprlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           L F+Tgs+r+P+ G+ +++   ++i+   + ++ lP ++TC+n+L+LP+Y ske+l  +L+ Ai++ +gF+l
   Q: 982  LLFLTGSDRIPIYGMSSVR---IIIQStLRGEQYLPVAHTCYNLLDLPKYRSKETLSMRLTQAIDHYEGFSL 1050
           ******************9...7777768999**************************************97 PP
   
Organism Pelodiscus sinensis
Protein Sequence
(Fasta)
MLCWGCWSFG QSGIGSNLQA IIPEPQVYGF MHDRNIKEVA CGGNHSVFLL ENGDVYTCGL 60
NTKGHLGHQR EGSKPEQIGA LADQHIVHVA CGESHCVALS DQGQIFSWGA GSDGQLGITT 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Psi-093832|E3,HECT|Pelodiscus sinensis
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TAGGCTAAGG CCCAGCCCAG CCGGAGGCAG CTGCTGGAGG TGAGTGGCGC TGCCGCCCTG 60
TCCGGGCTGC TCCCTGCTAG AGCCCGTGCA GGGGTGGGCA GCTTGGGGAA GCCCGGGGCC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Psi-093832|E3,HECT|Pelodiscus sinensis
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
Interpro

IPR000569--HECT_dom
IPR009091--RCC1/BLIP-II
IPR000408--Reg_chr_condens
PROSITE

PS50237--HECT
PS00626--RCC1_2
PS50012--RCC1_3
Pfam

PF00632--HECT
PF00415--RCC1
PRINTS

PR00633--RCCNDNSATION
SMART

SM00119--HECTc
Gene Ontology

GO:0005829--C:cytosol
GO:0004842--F:ubiquitin-protein transferase activity
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001673 Ailuropoda melanoleuca 85.73 0.00e+00 1846.00
IUUC-Apl-003535 Anas platyrhynchos 90.10 0.00e+00 1912.00
IUUC-Aca-005223 Anolis carolinensis 85.82 0.00e+00 1830.00
IUUC-Ame-010816 Astyanax mexicanus 65.17 0.00e+00 1142.00
IUUC-Bta-013373 Bos taurus 85.54 0.00e+00 1842.00
IUUC-Cel-018150 Caenorhabditis elegans 33.12 5.00e-154 538.00
IUUC-Cja-019609 Callithrix jacchus 85.82 0.00e+00 1843.00
IUUC-Cfa-021071 Canis familiaris 85.44 0.00e+00 1837.00
IUUC-Cpo-021548 Cavia porcellus 85.06 0.00e+00 1833.00
IUUC-Csa-023987 Chlorocebus sabaeus 85.63 0.00e+00 1840.00
IUUC-Cho-024325 Choloepus hoffmanni 86.96 0.00e+00 1080.00
IUUC-Dre-027472 Danio rerio 66.00 0.00e+00 1377.00
IUUC-Dno-029241 Dasypus novemcinctus 84.90 0.00e+00 1827.00
IUUC-Dor-030672 Dipodomys ordii 78.98 0.00e+00 987.00
IUUC-Ete-032642 Echinops telfairi 80.97 0.00e+00 1677.00
IUUC-Eca-033646 Equus caballus 85.63 0.00e+00 1841.00
IUUC-Eeu-035098 Erinaceus europaeus 74.94 0.00e+00 1221.00
IUUC-Fal-036952 Ficedula albicollis 90.01 0.00e+00 1907.00
IUUC-Gmo-039297 Gadus morhua 64.90 0.00e+00 1323.00
IUUC-Gga-040591 Gallus gallus 89.15 0.00e+00 1899.00
IUUC-Gac-041741 Gasterosteus aculeatus 64.71 0.00e+00 1370.00
IUUC-Ggo-044769 Gorilla gorilla 85.55 0.00e+00 1835.00
IUUC-Hsa-046066 Homo sapiens 85.63 0.00e+00 1839.00
IUUC-Itr-048311 Ictidomys tridecemlineatus 85.65 0.00e+00 1836.00
IUUC-Lch-050301 Latimeria chalumnae 73.07 0.00e+00 1589.00
IUUC-Loc-052803 Lepisosteus oculatus 66.45 0.00e+00 1431.00
IUUC-Laf-053364 Loxodonta africana 85.54 0.00e+00 1838.00
IUUC-Mcc-054930 Macaca mulatta 85.54 0.00e+00 1839.00
IUUC-Meu-056274 Macropus eugenii 74.31 0.00e+00 817.00
IUUC-Mga-059563 Meleagris gallopavo 89.72 0.00e+00 1905.00
IUUC-Mmr-060792 Microcebus murinus 84.49 0.00e+00 1808.00
IUUC-Mdo-062195 Monodelphis domestica 87.64 0.00e+00 1872.00
IUUC-Mmu-063855 Mus musculus 84.59 0.00e+00 1823.00
IUUC-Mpu-066308 Mustela putorius furo 85.63 0.00e+00 1842.00
IUUC-Mlu-066927 Myotis lucifugus 85.63 0.00e+00 1840.00
IUUC-Nle-070090 Nomascus leucogenys 85.63 0.00e+00 1840.00
IUUC-Opr-070891 Ochotona princeps 75.07 0.00e+00 1560.00
IUUC-Ont-072201 Oreochromis niloticus 63.46 0.00e+00 1319.00
IUUC-Ocu-074770 Oryctolagus cuniculus 85.54 0.00e+00 1837.00
IUUC-Ola-086550 Oryzias latipes 64.23 0.00e+00 1368.00
IUUC-Olu-087836 Ostreococcus lucimarinus 32.43 7.00e-39 154.00
IUUC-Oga-088831 Otolemur garnettii 85.35 0.00e+00 1836.00
IUUC-Oar-090449 Ovis aries 85.73 0.00e+00 1842.00
IUUC-Pan-092135 Papio anubis 85.55 0.00e+00 1835.00
IUUC-Pfo-097268 Poecilia formosa 65.05 0.00e+00 1368.00
IUUC-Pab-098249 Pongo abelii 85.35 0.00e+00 1833.00
IUUC-Pca-100855 Procavia capensis 80.76 0.00e+00 1243.00
IUUC-Pva-102506 Pteropus vampyrus 77.85 0.00e+00 1610.00
IUUC-Rno-105242 Rattus norvegicus 84.59 0.00e+00 1860.00
IUUC-Sar-113612 Sorex araneus 86.99 0.00e+00 676.00
IUUC-Ssc-115473 Sus scrofa 84.97 0.00e+00 1826.00
IUUC-Tgu-116974 Taeniopygia guttata 90.02 0.00e+00 1889.00
IUUC-Tru-118077 Takifugu rubripes 63.36 0.00e+00 1305.00
IUUC-Tsy-119619 Tarsius syrichta 75.36 0.00e+00 1621.00
IUUC-Tni-120807 Tetraodon nigroviridis 63.68 0.00e+00 1326.00
IUUC-Tbe-127640 Tupaia belangeri 81.73 0.00e+00 1709.00
IUUC-Ttr-129172 Tursiops truncatus 84.97 0.00e+00 1824.00
IUUC-Vpa-130442 Vicugna pacos 71.31 0.00e+00 1476.00
IUUC-Xtr-132194 Xenopus tropicalis 70.47 0.00e+00 1405.00
Created Date 25-Jun-2017

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