iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-053806

Ensembl Protein ID

ENSLAFP00000007701.3

UniProt Accession

G3T3A4; G3T3A4_LOXAF

Protein Name

Uncharacterized protein

Gene Name

LATS2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000009188.3	ENSLAFT00000009187.3	ENSLAFP00000007701.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	3.20e-06	27.5	100	137

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraa.nnnleaAveyLl 39
           + ++l++lv+ G+d+e a++aL ++ + ++eaA+ey+ 
   Q: 100  NRQMLQELVNAGCDQEMAVRALKQTgSRSIEAALEYIS 137
           669*********************************86 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MRPKTFPATT YSGNSRQRLQ EIREGLKQPS KSSAQGLPVG PNNDSSLDAK VLGGKDAARQ 60
QQQMRSTPKF GPYQKALREI RYSLLPFANE SGTSAAAEVN RQMLQELVNA GCDQEMAVRA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGGCCAA AGACTTTTCC TGCCACGACT TATTCTGGAA ATAGCAGGCA GCGATTGCAG 60
GAGATTCGCG AAGGGTTAAA GCAACCGTCC AAGTCTTCAG CTCAGGGGTT ACCAGTGGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR000961--AGC-kinase_C
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS
IPR015940--UBA
IPR009060--UBA-like

PROSITE

PS51285--AGC_KINASE_CTER
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50030--UBA

Pfam

PF00069--Pkinase

SMART

SM00133--S_TK_X
SM00220--S_TKc

Gene Ontology

GO:0005829--C:cytosol
GO:0005815--C:microtubule organizing center
GO:0005634--C:nucleus
GO:0000922--C:spindle pole
GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0034613--P:cellular protein localization
GO:0000082--P:G1/S transition of mitotic cell cycle
GO:0035329--P:hippo signaling
GO:0009755--P:hormone-mediated signaling pathway
GO:0001827--P:inner cell mass cell fate commitment
GO:0001828--P:inner cell mass cellular morphogenesis
GO:0030216--P:keratinocyte differentiation
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:0045736--P:negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0046620--P:regulation of organ growth

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001960	Ailuropoda melanoleuca	85.06	0.00e+00	1893.00
IUUC-Apl-003521	Anas platyrhynchos	74.70	0.00e+00	1297.00
IUUC-Aca-004995	Anolis carolinensis	74.57	0.00e+00	1580.00
IUUC-Ame-011481	Astyanax mexicanus	62.41	0.00e+00	1245.00
IUUC-Bta-012618	Bos taurus	85.21	0.00e+00	998.00
IUUC-Cja-019430	Callithrix jacchus	82.66	0.00e+00	1753.00
IUUC-Cfa-020687	Canis familiaris	84.62	0.00e+00	1840.00
IUUC-Cpo-021985	Cavia porcellus	84.44	0.00e+00	1070.00
IUUC-Csa-023534	Chlorocebus sabaeus	94.41	0.00e+00	975.00
IUUC-Cho-024363	Choloepus hoffmanni	81.03	0.00e+00	731.00
IUUC-Dre-027538	Danio rerio	62.27	0.00e+00	1260.00
IUUC-Dno-029126	Dasypus novemcinctus	83.41	0.00e+00	1890.00
IUUC-Dor-030172	Dipodomys ordii	79.84	0.00e+00	1511.00
IUUC-Eca-033868	Equus caballus	84.44	0.00e+00	1811.00
IUUC-Eeu-034881	Erinaceus europaeus	67.96	0.00e+00	1310.00
IUUC-Fca-036203	Felis catus	78.75	0.00e+00	1661.00
IUUC-Fal-036668	Ficedula albicollis	75.75	0.00e+00	1680.00
IUUC-Gmo-039195	Gadus morhua	85.51	0.00e+00	780.00
IUUC-Gac-041789	Gasterosteus aculeatus	84.25	0.00e+00	867.00
IUUC-Ggo-044904	Gorilla gorilla	80.62	0.00e+00	1684.00
IUUC-Hsa-046254	Homo sapiens	83.38	0.00e+00	1711.00
IUUC-Itr-047948	Ictidomys tridecemlineatus	83.59	0.00e+00	1552.00
IUUC-Lch-050079	Latimeria chalumnae	67.70	0.00e+00	1491.00
IUUC-Loc-052265	Lepisosteus oculatus	66.80	0.00e+00	924.00
IUUC-Mcc-055253	Macaca mulatta	83.32	0.00e+00	1721.00
IUUC-Meu-056509	Macropus eugenii	83.30	0.00e+00	805.00
IUUC-Mga-059600	Meleagris gallopavo	75.31	0.00e+00	1674.00
IUUC-Mmr-061586	Microcebus murinus	83.98	0.00e+00	1685.00
IUUC-Mdo-062126	Monodelphis domestica	76.04	0.00e+00	1626.00
IUUC-Mmu-063164	Mus musculus	78.55	0.00e+00	1585.00
IUUC-Mpu-065992	Mustela putorius furo	84.34	0.00e+00	1882.00
IUUC-Mlu-067728	Myotis lucifugus	77.00	0.00e+00	1582.00
IUUC-Nle-069546	Nomascus leucogenys	83.59	0.00e+00	1704.00
IUUC-Opr-070872	Ochotona princeps	80.74	0.00e+00	1666.00
IUUC-Ont-072296	Oreochromis niloticus	85.97	0.00e+00	913.00
IUUC-Ocu-074068	Oryctolagus cuniculus	80.51	0.00e+00	1694.00
IUUC-Ola-086756	Oryzias latipes	59.31	0.00e+00	1179.00
IUUC-Oga-089066	Otolemur garnettii	83.98	0.00e+00	1807.00
IUUC-Oar-090416	Ovis aries	84.87	0.00e+00	996.00
IUUC-Ptr-091247	Pan troglodytes	83.20	0.00e+00	1731.00
IUUC-Pan-092438	Papio anubis	83.23	0.00e+00	1719.00
IUUC-Psi-093920	Pelodiscus sinensis	75.18	0.00e+00	1671.00
IUUC-Pfo-096334	Poecilia formosa	84.49	0.00e+00	890.00
IUUC-Pab-098452	Pongo abelii	83.14	0.00e+00	1741.00
IUUC-Pca-101081	Procavia capensis	86.50	0.00e+00	1917.00
IUUC-Rno-105102	Rattus norvegicus	79.15	0.00e+00	1579.00
IUUC-Sha-106917	Sarcophilus harrisii	76.57	0.00e+00	1659.00
IUUC-Sar-113711	Sorex araneus	77.02	0.00e+00	1493.00
IUUC-Tgu-116553	Taeniopygia guttata	76.85	0.00e+00	1671.00
IUUC-Tru-118069	Takifugu rubripes	86.12	0.00e+00	899.00
IUUC-Tni-120617	Tetraodon nigroviridis	81.73	0.00e+00	885.00
IUUC-Ttr-129256	Tursiops truncatus	70.51	0.00e+00	1353.00
IUUC-Xtr-132593	Xenopus tropicalis	70.82	0.00e+00	1504.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence