iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-091186

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AACZ03022963

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000030309.2	ENSPTRT00000058562.2	ENSPTRP00000051576.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	99.01	1.00e-53	205.00	IUUC-Hsa-046547

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MPRRAENWDE AEVGAEEAGV EKYGPEEDGG EESGAQERPH LWLFRDAGTH DGLLVNQTEL 60
FVPSLNVDGQ PIFANITLPV YTLKERCLQV VRSLVKPENY RRLDIVRSLY EDLEDHPNVQ 120

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Nucleotide Sequence
(Fasta)

ATGCCCCGGA GGGCGGAGAA CTGGGACGAG GCCGAGGTAG GCGCGGAGGA GGCAGGCGTC 60
GAAAAGTACG GCCCTGAAGA AGACGGCGGG GAGGAGTCGG GCGCCCAGGA GTCGGCCCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR002714--VHL
IPR024048--VHL_alpha_dom
IPR024053--VHL_beta_dom
IPR022772--VHL_tumour_suppress_b/a_dom

Pfam

PF01847--VHL
PF17211--VHL_C

Gene Ontology

GO:0005929--C:cilium
GO:0031462--C:Cul2-RING ubiquitin ligase complex
GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0030891--C:VCB complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0001525--P:angiogenesis
GO:0043534--P:blood vessel endothelial cell migration
GO:0061073--P:ciliary body morphogenesis
GO:0030198--P:extracellular matrix organization
GO:0048069--P:eye pigmentation
GO:0048877--P:homeostasis of number of retina cells
GO:0061072--P:iris morphogenesis
GO:0006582--P:melanin metabolic process
GO:0045602--P:negative regulation of endothelial cell differentiation
GO:0010629--P:negative regulation of gene expression
GO:1902072--P:negative regulation of hypoxia-inducible factor-1alpha signaling pathway
GO:0070244--P:negative regulation of thymocyte apoptotic process
GO:0006607--P:NLS-bearing protein import into nucleus
GO:0003310--P:pancreatic A cell differentiation
GO:0050679--P:positive regulation of epithelial cell proliferation
GO:0010498--P:proteasomal protein catabolic process
GO:0016567--P:protein ubiquitination
GO:2001233--P:regulation of apoptotic signaling pathway
GO:1903827--P:regulation of cellular protein localization
GO:0003309--P:type B pancreatic cell differentiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002327	Ailuropoda melanoleuca	82.35	4.00e-49	187.00
IUUC-Apl-003580	Anas platyrhynchos	71.43	2.00e-26	109.00
IUUC-Aca-004492	Anolis carolinensis	81.93	5.00e-36	143.00
IUUC-Ame-011818	Astyanax mexicanus	56.18	1.00e-25	109.00
IUUC-Bta-013459	Bos taurus	92.00	5.00e-49	186.00
IUUC-Cja-019826	Callithrix jacchus	97.03	5.00e-53	200.00
IUUC-Cfa-021280	Canis familiaris	93.94	6.00e-50	190.00
IUUC-Cpo-022544	Cavia porcellus	92.78	1.00e-48	185.00
IUUC-Csa-023644	Chlorocebus sabaeus	97.03	6.00e-53	200.00
IUUC-Cho-024479	Choloepus hoffmanni	93.10	5.00e-26	109.00
IUUC-Dre-028350	Danio rerio	50.56	8.00e-13	66.20
IUUC-Dno-029207	Dasypus novemcinctus	88.07	7.00e-52	196.00
IUUC-Dor-030912	Dipodomys ordii	84.48	6.00e-23	100.00
IUUC-Dme-031988	Drosophila melanogaster	28.00	2.80e-01	28.10
IUUC-Eca-034007	Equus caballus	97.50	3.00e-20	89.40
IUUC-Fca-036350	Felis catus	92.08	2.00e-48	185.00
IUUC-Fal-037192	Ficedula albicollis	72.04	7.00e-33	132.00
IUUC-Gmo-038921	Gadus morhua	58.59	2.00e-25	108.00
IUUC-Gga-041016	Gallus gallus	73.12	3.00e-34	137.00
IUUC-Gac-042560	Gasterosteus aculeatus	53.93	4.00e-20	90.90
IUUC-Ggo-045419	Gorilla gorilla	99.01	2.00e-54	205.00
IUUC-Hsa-046547	Homo sapiens	99.01	2.00e-54	204.00
IUUC-Itr-048225	Ictidomys tridecemlineatus	92.93	8.00e-50	189.00
IUUC-Lch-050463	Latimeria chalumnae	67.78	6.00e-32	130.00
IUUC-Loc-052053	Lepisosteus oculatus	57.95	2.00e-27	114.00
IUUC-Laf-053893	Loxodonta africana	90.10	4.00e-49	186.00
IUUC-Mcc-055347	Macaca mulatta	61.98	1.00e-55	208.00
IUUC-Mdo-062169	Monodelphis domestica	82.50	1.00e-15	74.30
IUUC-Mmu-064366	Mus musculus	93.18	2.00e-44	171.00
IUUC-Mpu-066593	Mustela putorius furo	91.92	3.00e-49	187.00
IUUC-Mlu-066926	Myotis lucifugus	93.07	5.00e-51	193.00
IUUC-Nle-069724	Nomascus leucogenys	98.02	9.00e-54	202.00
IUUC-Opr-070679	Ochotona princeps	76.32	2.00e-46	177.00
IUUC-Ont-071332	Oreochromis niloticus	55.32	2.00e-24	105.00
IUUC-Ola-086869	Oryzias latipes	50.52	2.00e-20	91.70
IUUC-Oga-089124	Otolemur garnettii	92.16	4.00e-49	187.00
IUUC-Oar-089799	Ovis aries	90.82	1.00e-48	184.00
IUUC-Pan-092150	Papio anubis	96.04	2.00e-52	197.00
IUUC-Psi-094039	Pelodiscus sinensis	61.86	1.00e-39	155.00
IUUC-Pma-094129	Petromyzon marinus	50.56	4.00e-17	80.90
IUUC-Pfo-096892	Poecilia formosa	52.81	2.00e-20	91.70
IUUC-Pab-097822	Pongo abelii	98.02	9.00e-54	202.00
IUUC-Pca-101058	Procavia capensis	85.15	2.00e-43	168.00
IUUC-Pva-102932	Pteropus vampyrus	94.06	3.00e-51	194.00
IUUC-Rno-105050	Rattus norvegicus	89.11	1.00e-49	189.00
IUUC-Sha-106738	Sarcophilus harrisii	77.78	6.00e-42	161.00
IUUC-Ssc-115973	Sus scrofa	88.00	3.00e-47	181.00
IUUC-Tgu-116663	Taeniopygia guttata	71.43	6.00e-33	131.00
IUUC-Tru-118654	Takifugu rubripes	56.18	5.00e-23	99.80
IUUC-Ttr-128418	Tursiops truncatus	92.08	9.00e-50	189.00
IUUC-Vpa-130268	Vicugna pacos	97.50	2.00e-18	84.70
IUUC-Xtr-132506	Xenopus tropicalis	67.05	2.00e-31	128.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence