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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-046986
Ensembl Protein ID ENSP00000329200.2
UniProt Accession Q96MF2; B4DUK9; Q96HU5; STAC3_HUMAN
Genbank Protein ID BAB71343.1; BAG62371.1; EAW97005.1; AAH08069.1
Protein Name SH3 and cysteine-rich domain-containing protein 3
Genbank Nucleotide ID AK057013; AK300688; AC137834; BC008069
Gene Name STAC3
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000185482.7 ENST00000332782.6 ENSP00000329200.2
ENSG00000185482.7 ENST00000557176.5 ENSP00000450740.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMIC
DNA & RNA Element
UTRdbAREsitecircBaseCircNet
microRNATRANSFACRepTarmiRNAMap
miRcodeRAID2
Protein-protein Interaction
IIDPINAHINTMentha
InWeb_IM
Protein 3D Structure
PDBMMDB
Disease-associated Variation
ClinVarGWASdbOMIM
Post-translational Modifications (PTMs)
dbPAFPhosphositePlus
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 1.20e-15 58.9 248 305
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           + +++ +ly ++a ++d+L +  G++++vi  ++ +e+W++g  +  +k G+fP nF+ +++
   Q: 248  QSHYFVALYRFKALEKDDLDFPPGEKITVI--DDSNEEWWRG--KIGEKVGFFPPNFIIRVR 305
           578999************************..999*******..8*************9986 PP
   
Organism Homo sapiens
Functional Description
(View)

Functional Description


     In skeletal muscles contraction, may play a role in neuromuscular synaptic transmission.
 In skeletal muscles contraction, may play a role in neuromuscular synaptic transmission.
Protein Sequence
(Fasta)
MTEKEVLESP KPSFPAETRQ SGLQRLKQLL RKGSTGTKEM ELPPEPQANG EAVGAGGGPI 60
YYIYEEEEEE EEEEEEPPPE PPKLVNDKPH KFKDHFFKKP KFCDVCARMI VLNNKFGLRC 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046986|UBD,SH3|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CCCTGTCATT TCAGCCCTGA CACCAAGGCA GGAGGCTAGG AGGTCTACAA ATAGCGACTG 60
GGTAGCTGGT GTGAACACAG GGGGTACTGG GGGGGCTTAG CCCCCAAGGA AGAGGACCAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046986|UBD,SH3|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0225--Disease mutation
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0728--SH3 domain
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR002219--PE/DAG-bd
IPR011511--SH3_2
IPR001452--SH3_domain
PROSITE

PS50002--SH3
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2
Pfam

PF00130--C1_1
PF00018--SH3_1
PF07653--SH3_2
PRINTS

PR00452--SH3DOMAIN
SMART

SM00109--C1
SM00326--SH3
Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0042802--F:identical protein binding
GO:0046872--F:metal ion binding
GO:0035556--P:intracellular signal transduction
GO:0007274--P:neuromuscular synaptic transmission
GO:0003009--P:skeletal muscle contraction
GO:0048741--P:skeletal muscle fiber development
KEGG hsa:246329
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001628 Ailuropoda melanoleuca 96.70 2.00e-177 614.00
IUUC-Apl-003476 Anas platyrhynchos 75.54 1.00e-145 509.00
IUUC-Aca-004927 Anolis carolinensis 73.32 1.00e-126 446.00
IUUC-Bta-013019 Bos taurus 96.43 6.00e-175 606.00
IUUC-Cja-019413 Callithrix jacchus 97.80 3.00e-179 620.00
IUUC-Cfa-020850 Canis familiaris 96.43 3.00e-180 624.00
IUUC-Cpo-022550 Cavia porcellus 95.60 3.00e-174 604.00
IUUC-Csa-023317 Chlorocebus sabaeus 99.18 0.00e+00 631.00
IUUC-Cho-024370 Choloepus hoffmanni 82.94 4.00e-121 427.00
IUUC-Dre-027776 Danio rerio 63.16 2.00e-104 372.00
IUUC-Dno-030075 Dasypus novemcinctus 94.51 3.00e-178 617.00
IUUC-Dor-030293 Dipodomys ordii 89.29 3.00e-153 534.00
IUUC-Dme-032167 Drosophila melanogaster 39.50 2.00e-21 99.00
IUUC-Eca-034242 Equus caballus 96.70 0.00e+00 650.00
IUUC-Eeu-035253 Erinaceus europaeus 85.16 4.00e-154 537.00
IUUC-Fal-036603 Ficedula albicollis 71.22 1.00e-120 426.00
IUUC-Gmo-038819 Gadus morhua 65.03 1.00e-99 356.00
IUUC-Gac-041411 Gasterosteus aculeatus 62.85 8.00e-92 330.00
IUUC-Ggo-045153 Gorilla gorilla 99.45 0.00e+00 634.00
IUUC-Itr-047869 Ictidomys tridecemlineatus 94.52 3.00e-169 587.00
IUUC-Lch-050210 Latimeria chalumnae 66.58 2.00e-127 448.00
IUUC-Loc-052713 Lepisosteus oculatus 67.59 3.00e-118 418.00
IUUC-Laf-053842 Loxodonta africana 95.60 9.00e-172 595.00
IUUC-Mcc-054677 Macaca mulatta 98.90 0.00e+00 631.00
IUUC-Meu-055955 Macropus eugenii 76.65 1.00e-119 422.00
IUUC-Mmr-060715 Microcebus murinus 96.15 2.00e-165 575.00
IUUC-Mmu-063329 Mus musculus 89.04 1.00e-147 515.00
IUUC-Mpu-066119 Mustela putorius furo 97.25 4.00e-178 617.00
IUUC-Mlu-068094 Myotis lucifugus 95.60 0.00e+00 630.00
IUUC-Nle-069394 Nomascus leucogenys 99.18 0.00e+00 631.00
IUUC-Opr-070364 Ochotona princeps 100.00 2.00e-70 259.00
IUUC-Ont-072682 Oreochromis niloticus 65.34 1.00e-94 339.00
IUUC-Ocu-074004 Oryctolagus cuniculus 97.97 9.00e-168 582.00
IUUC-Ola-087262 Oryzias latipes 65.84 6.00e-92 330.00
IUUC-Oga-088079 Otolemur garnettii 82.56 6.00e-128 449.00
IUUC-Oar-089375 Ovis aries 96.43 2.00e-175 607.00
IUUC-Ptr-091572 Pan troglodytes 99.45 0.00e+00 635.00
IUUC-Pan-091976 Papio anubis 98.35 0.00e+00 628.00
IUUC-Pma-094461 Petromyzon marinus 43.25 2.00e-66 245.00
IUUC-Pfo-096226 Poecilia formosa 64.11 8.00e-94 337.00
IUUC-Pab-097731 Pongo abelii 97.73 4.00e-119 422.00
IUUC-Pca-100482 Procavia capensis 94.51 8.00e-171 592.00
IUUC-Pva-102329 Pteropus vampyrus 88.82 6.00e-129 453.00
IUUC-Rno-105196 Rattus norvegicus 89.86 1.00e-148 519.00
IUUC-Sha-106995 Sarcophilus harrisii 89.59 7.00e-153 533.00
IUUC-Sar-113724 Sorex araneus 87.15 3.00e-79 288.00
IUUC-Ssc-115771 Sus scrofa 96.46 2.00e-177 615.00
IUUC-Tru-118166 Takifugu rubripes 65.03 1.00e-99 356.00
IUUC-Tsy-119347 Tarsius syrichta 96.15 8.00e-176 609.00
IUUC-Tni-120179 Tetraodon nigroviridis 70.24 3.00e-115 408.00
IUUC-Ttr-128506 Tursiops truncatus 95.61 9.00e-175 605.00
IUUC-Xtr-131834 Xenopus tropicalis 74.69 3.00e-126 444.00
Created Date 25-Jun-2017

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