iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cin-025454

Ensembl Protein ID

ENSCINP00000033311.1

UniProt Accession

H2XUH7; H2XUH7_CIOIN

Genbank Protein ID

ENSCINP00000033311

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

EAAA01000660

Gene Name

uhrf2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCING00000020404.1	ENSCINT00000031507.1	ENSCINP00000033311.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	7.70e-09	35.4	294	341
ULD/UDP/UBQ/UBQ_Other	5.30e-11	42.1	1	75

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 4    ClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrs 53
           C+vCge+ + +k  + C++C+  fH  Cl+++  ++lp++++w+Cp C++
   Q: 294  CHVCGEKRAFDK-TLLCDECNLPFHTFCLNPP-LDNLPEEDDWYCPLCCQ 341
           *********985.999****************.***************86 PP

ULD/UDP/UBQ/UBQ_Other

   S: 1    vqvtvksldgs.eltlk.vnpsdtVaeLKekiekklgippeqqrLiykGkiLeddktLadyglkdgstihllekk 73
           ++++v+++dg+ + ++  +++ + + +L+e i +k+++ p  qrL ++Gk Led+ +L dy++  +  + lle+k
   Q: 1    MWIRVRTMDGKrSEQVDgLSKLTKIEDLRELIMEKFSVEPSLQRLFFRGKQLEDGYSLFDYDVGLNALVQLLERK 75
           689************************************************************999999998876 PP

Organism

Ciona intestinalis

Protein Sequence
(Fasta)

MWIRVRTMDG KRSEQVDGLS KLTKIEDLRE LIMEKFSVEP SLQRLFFRGK QLEDGYSLFD 60
YDVGLNALVQ LLERKVIKEV ETQQENETPA SPSDTDSGIE TAENVQEVVE DIPSTSCEGL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGGATCA GGGTTCGAAC AATGGACGGT AAAAGGTCCG AGCAAGTTGA TGGCCTTTCT 60
AAACTAACGA AAATCGAAGA TTTGCGAGAA CTTATAATGG AAAAGTTTAG CGTCGAACCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR015947--PUA-like_domain
IPR014722--Rib_L2_dom2
IPR003105--SRA_YDG
IPR021991--TTD_dom
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50053--UBIQUITIN_2
PS51015--YDG
PS50016--ZF_PHD_2
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00628--PHD
PF02182--SAD_SRA
PF12148--TTD
PF00240--ubiquitin

SMART

SM00249--PHD
SM00184--RING
SM00466--SRA
SM00213--UBQ

Gene Ontology

GO:0005720--C:nuclear heterochromatin
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0010216--P:maintenance of DNA methylation
GO:0016567--P:protein ubiquitination
GO:0090308--P:regulation of methylation-dependent chromatin silencing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000242	Aegilops tauschii	35.97	4.00e-43	167.00
IUUC-Aml-001285	Ailuropoda melanoleuca	52.50	0.00e+00	762.00
IUUC-Atr-002603	Amborella trichopoda	34.25	2.00e-42	165.00
IUUC-Apl-003819	Anas platyrhynchos	53.02	0.00e+00	746.00
IUUC-Aca-005287	Anolis carolinensis	48.61	0.00e+00	747.00
IUUC-Aly-006276	Arabidopsis lyrata	35.35	1.00e-46	179.00
IUUC-Ath-006667	Arabidopsis thaliana	35.12	2.00e-45	175.00
IUUC-Ame-011845	Astyanax mexicanus	53.48	0.00e+00	783.00
IUUC-Bta-012600	Bos taurus	52.65	0.00e+00	760.00
IUUC-Bci-013703	Botrytis cinerea	29.35	7.00e-09	53.90
IUUC-Bdi-014586	Brachypodium distachyon	39.23	6.00e-43	167.00
IUUC-Bol-015519	Brassica oleracea	34.88	5.00e-45	174.00
IUUC-Bra-017110	Brassica rapa	35.12	2.00e-45	175.00
IUUC-Cja-018864	Callithrix jacchus	50.94	0.00e+00	758.00
IUUC-Cfa-020558	Canis familiaris	52.51	0.00e+00	762.00
IUUC-Cpo-022125	Cavia porcellus	52.53	0.00e+00	772.00
IUUC-Cre-022645	Chlamydomonas reinhardtii	33.17	1.00e-21	97.10
IUUC-Csa-023649	Chlorocebus sabaeus	47.95	0.00e+00	722.00
IUUC-Cho-024857	Choloepus hoffmanni	47.04	6.00e-126	443.00
IUUC-Cgl-026498	Colletotrichum gloeosporioides	29.37	3.00e-07	48.90
IUUC-Cne-026942	Cryptococcus neoformans	43.90	2.00e-23	100.00
IUUC-Dre-028200	Danio rerio	54.38	0.00e+00	813.00
IUUC-Dno-029950	Dasypus novemcinctus	46.95	0.00e+00	680.00
IUUC-Dor-031084	Dipodomys ordii	51.85	0.00e+00	776.00
IUUC-Ete-032375	Echinops telfairi	41.04	5.00e-54	204.00
IUUC-Eca-033266	Equus caballus	53.25	0.00e+00	756.00
IUUC-Eeu-035077	Erinaceus europaeus	64.19	6.00e-100	356.00
IUUC-Fca-035685	Felis catus	73.76	9.00e-88	316.00
IUUC-Fal-037082	Ficedula albicollis	49.58	0.00e+00	750.00
IUUC-Gmo-039452	Gadus morhua	52.33	0.00e+00	780.00
IUUC-Gga-040484	Gallus gallus	53.54	0.00e+00	808.00
IUUC-Gac-042196	Gasterosteus aculeatus	54.10	0.00e+00	808.00
IUUC-Gma-042831	Glycine max	34.26	3.00e-43	168.00
IUUC-Ggo-045414	Gorilla gorilla	51.12	0.00e+00	767.00
IUUC-Hsa-046236	Homo sapiens	51.12	0.00e+00	766.00
IUUC-Hvu-047471	Hordeum vulgare	36.34	2.00e-42	166.00
IUUC-Itr-047867	Ictidomys tridecemlineatus	51.70	0.00e+00	765.00
IUUC-Lch-050162	Latimeria chalumnae	57.97	0.00e+00	661.00
IUUC-Lpe-050756	Leersia perrieri	34.92	1.00e-40	160.00
IUUC-Loc-051806	Lepisosteus oculatus	53.54	0.00e+00	809.00
IUUC-Lma-052953	Leptosphaeria maculans	26.51	4.00e-11	61.60
IUUC-Laf-053671	Loxodonta africana	51.92	0.00e+00	783.00
IUUC-Mcc-055513	Macaca mulatta	50.75	0.00e+00	775.00
IUUC-Meu-056189	Macropus eugenii	40.21	4.00e-76	278.00
IUUC-Mtr-057930	Medicago truncatula	34.17	3.00e-43	168.00
IUUC-Mla-058836	Melampsora laricipopulina	44.44	5.00e-31	127.00
IUUC-Mga-059759	Meleagris gallopavo	52.34	0.00e+00	737.00
IUUC-Mvi-060378	Microbotryum violaceum	48.30	1.00e-37	149.00
IUUC-Mmr-060646	Microcebus murinus	47.23	0.00e+00	689.00
IUUC-Mdo-061911	Monodelphis domestica	53.16	0.00e+00	788.00
IUUC-Mmu-063738	Mus musculus	50.57	0.00e+00	756.00
IUUC-Mac-064697	Musa acuminata	37.60	2.00e-43	169.00
IUUC-Mpu-065696	Mustela putorius furo	52.20	0.00e+00	763.00
IUUC-Mlu-067538	Myotis lucifugus	50.86	0.00e+00	763.00
IUUC-Nle-069901	Nomascus leucogenys	46.57	0.00e+00	632.00
IUUC-Opr-070813	Ochotona princeps	42.27	9.00e-94	336.00
IUUC-Ont-072292	Oreochromis niloticus	54.81	0.00e+00	796.00
IUUC-Oan-073109	Ornithorhynchus anatinus	57.55	1.00e-144	504.00
IUUC-Ocu-074748	Oryctolagus cuniculus	46.81	0.00e+00	634.00
IUUC-Oba-075108	Oryza barthii	35.18	3.00e-41	162.00
IUUC-Obr-076572	Oryza brachyantha	37.86	2.00e-41	162.00
IUUC-Ogl-077177	Oryza glaberrima	35.18	5.00e-41	161.00
IUUC-Ogu-078298	Oryza glumaepatula	35.18	4.00e-41	161.00
IUUC-Oin-079911	Oryza indica	35.18	4.00e-41	161.00
IUUC-Olo-080527	Oryza longistaminata	44.21	1.00e-28	120.00
IUUC-Ome-081137	Oryza meridionalis	32.25	2.00e-32	133.00
IUUC-Oni-082620	Oryza nivara	35.18	4.00e-41	161.00
IUUC-Opu-083974	Oryza punctata	35.34	2.00e-41	162.00
IUUC-Oru-084985	Oryza rufipogon	33.91	3.00e-41	162.00
IUUC-Osa-085339	Oryza sativa	35.18	5.00e-41	161.00
IUUC-Ola-086416	Oryzias latipes	52.34	0.00e+00	764.00
IUUC-Oga-088221	Otolemur garnettii	51.38	0.00e+00	773.00
IUUC-Oar-089604	Ovis aries	50.19	0.00e+00	698.00
IUUC-Ptr-090559	Pan troglodytes	51.13	0.00e+00	769.00
IUUC-Pan-092855	Papio anubis	50.75	0.00e+00	776.00
IUUC-Psi-093033	Pelodiscus sinensis	48.12	0.00e+00	683.00
IUUC-Pma-094339	Petromyzon marinus	53.79	0.00e+00	745.00
IUUC-Ppa-095940	Physcomitrella patens	34.40	1.00e-43	170.00
IUUC-Pfo-096243	Poecilia formosa	52.60	0.00e+00	775.00
IUUC-Pab-098243	Pongo abelii	51.06	0.00e+00	754.00
IUUC-Pop-099357	Populus trichocarpa	34.47	2.00e-47	182.00
IUUC-Pca-100503	Procavia capensis	49.44	0.00e+00	712.00
IUUC-Ppe-101961	Prunus persica	37.43	8.00e-47	180.00
IUUC-Pva-102266	Pteropus vampyrus	47.48	0.00e+00	696.00
IUUC-Pgr-103644	Puccinia graminis	46.34	1.00e-28	120.00
IUUC-Ptt-103867	Puccinia triticina	43.39	2.00e-29	122.00
IUUC-Rno-105345	Rattus norvegicus	50.58	0.00e+00	755.00
IUUC-Sha-106618	Sarcophilus harrisii	52.75	0.00e+00	787.00
IUUC-Smo-109556	Selaginella moellendorffii	37.21	8.00e-41	160.00
IUUC-Sit-110588	Setaria italica	33.66	1.00e-41	163.00
IUUC-Sly-111415	Solanum lycopersicum	34.94	9.00e-47	180.00
IUUC-Stu-112842	Solanum tuberosum	34.38	2.00e-45	176.00
IUUC-Sar-113546	Sorex araneus	42.47	7.00e-63	234.00
IUUC-Sbi-114726	Sorghum bicolor	35.73	2.00e-42	166.00
IUUC-Sre-115182	Sporisorium reilianum	44.13	7.00e-28	117.00
IUUC-Ssc-116081	Sus scrofa	52.36	0.00e+00	767.00
IUUC-Tgu-116538	Taeniopygia guttata	57.05	0.00e+00	684.00
IUUC-Tru-117599	Takifugu rubripes	53.69	0.00e+00	767.00
IUUC-Tsy-119249	Tarsius syrichta	47.58	0.00e+00	634.00
IUUC-Tni-120750	Tetraodon nigroviridis	50.64	0.00e+00	727.00
IUUC-Tca-121614	Theobroma cacao	34.76	2.00e-44	172.00
IUUC-Tae-123299	Triticum aestivum	35.77	2.00e-42	166.00
IUUC-Tme-127149	Tuber melanosporum	46.20	9.00e-23	100.00
IUUC-Tbe-127823	Tupaia belangeri	47.80	1.00e-151	528.00
IUUC-Ttr-128522	Tursiops truncatus	52.20	0.00e+00	769.00
IUUC-Vpa-130073	Vicugna pacos	46.29	0.00e+00	688.00
IUUC-Vvi-131413	Vitis vinifera	47.66	2.00e-38	152.00
IUUC-Xtr-132432	Xenopus tropicalis	52.67	0.00e+00	781.00
IUUC-Xma-133516	Xiphophorus maculatus	53.51	0.00e+00	794.00
IUUC-Zma-135894	Zea mays	35.99	9.00e-42	164.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence