iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088854

Ensembl Protein ID

ENSOGAP00000003227.2

UniProt Accession

H0WN55; H0WN55_OTOGA

Genbank Protein ID

ENSOGAP00000003227

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03156907

Gene Name

FAF1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000003624.2	ENSOGAT00000003627.2	ENSOGAP00000003227.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	9.30e-08	32.0	5	45
ULD/UDP/UFD/UBX	4.10e-20	72.1	569	646
ULD/UDP/UBQ/UBQ_Other	1.10e-10	41.3	110	169

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 1    sededkleqlve.MGF.dreealqaLraannnleaAveyLl 39
           +++e++l+ +++ +G+ + +ea++ L+++n++l aA++ ++
   Q: 5    MDREMILADFQAcTGIeNIDEAITLLEQNNWDLVAAINGVI 45
           689**********************************9875 PP

ULD/UDP/UFD/UBX

   S: 2    tteqatlqiRlpdGkrlvrkFpssttleqiyqfveyllvessdpFeLvspfPrrtlkpeehmstlqeagLvpsgsllve 80
           +++ ++l+iR+p+G++l+r+F +s++l+ +++fv+ ++++++d+F+L+s+fPrr++++ + +++l e +L+p+++l++e
   Q: 569  AEPVSKLRIRTPSGEFLERRFLASNKLQIVFDFVA-SKGFPWDEFKLLSTFPRRDITQLDPNKSLLEVKLFPQETLFLE 646
           56799******************************.****************************************986 PP

ULD/UDP/UBQ/UBQ_Other

   S: 12   eltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiL...eddktLadyglkdgstihll 70
           + ++ ++ s+tV+e+K+ +e +l ip+   ++++kG      ed   L++++l+ ++ +++l
   Q: 110  NVDVVLEDSCTVGEIKQILENELQIPMS--KMLLKGWKTgdvEDSTILKSLHLPKNNSLYVL 169
           5566678999****************77..899997776666***************99987 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MASNMDREMI LADFQACTGI ENIDEAITLL EQNNWDLVAA INGVIPQENG ILQSEYGGET 60
VTGPAFNPAN HPAPASTPSS SAFRPVMPSR QIVERQPRML DFRVEYRDRN VDVVLEDSCT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCAGGTGCGC GCTTCGCTCC CTCAGCCGCA GAACTCGGCG GCCGCCATGG CGTCCAACAT 60
GGACCGGGAG ATGATCCTGG CGGATTTTCA GGTGAAGTAT CTGGCCCTGT GCCCCTCCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR033043--FAF1_UBX
IPR012336--Thioredoxin-like_fold
IPR006577--UAS
IPR029071--Ubiquitin-rel_dom
IPR001012--UBX_dom

PROSITE

PS50033--UBX

Pfam

PF00789--UBX

SMART

SM00594--UAS
SM00166--UBX

Gene Ontology

GO:0005829--C:cytosol
GO:0005635--C:nuclear envelope
GO:0048471--C:perinuclear region of cytoplasm
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:0008219--P:cell death
GO:0007253--P:cytoplasmic sequestering of NF-kappaB
GO:1902043--P:positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:0031334--P:positive regulation of protein complex assembly
GO:0030155--P:regulation of cell adhesion
GO:0042176--P:regulation of protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002153	Ailuropoda melanoleuca	96.30	0.00e+00	1222.00
IUUC-Apl-004127	Anas platyrhynchos	90.44	0.00e+00	1145.00
IUUC-Aca-005188	Anolis carolinensis	89.64	0.00e+00	1127.00
IUUC-Ame-010696	Astyanax mexicanus	77.27	0.00e+00	875.00
IUUC-Bta-012965	Bos taurus	97.08	0.00e+00	1226.00
IUUC-Cel-018420	Caenorhabditis elegans	29.20	3.00e-29	123.00
IUUC-Cja-019128	Callithrix jacchus	96.63	0.00e+00	1243.00
IUUC-Cfa-021201	Canis familiaris	96.04	0.00e+00	904.00
IUUC-Cpo-021475	Cavia porcellus	95.61	0.00e+00	902.00
IUUC-Csa-024076	Chlorocebus sabaeus	97.38	0.00e+00	1229.00
IUUC-Cho-025067	Choloepus hoffmanni	83.36	0.00e+00	1070.00
IUUC-Cin-025663	Ciona intestinalis	43.79	9.00e-69	253.00
IUUC-Csv-025894	Ciona savignyi	34.82	1.00e-72	267.00
IUUC-Dre-027508	Danio rerio	75.15	0.00e+00	947.00
IUUC-Dno-029336	Dasypus novemcinctus	96.46	0.00e+00	1205.00
IUUC-Dor-030218	Dipodomys ordii	89.52	0.00e+00	1101.00
IUUC-Dme-031581	Drosophila melanogaster	33.00	4.00e-95	342.00
IUUC-Ete-032860	Echinops telfairi	74.12	0.00e+00	667.00
IUUC-Eca-034321	Equus caballus	97.87	0.00e+00	1055.00
IUUC-Eeu-034844	Erinaceus europaeus	72.78	2.00e-142	499.00
IUUC-Fca-036575	Felis catus	98.67	0.00e+00	730.00
IUUC-Fal-037128	Ficedula albicollis	90.78	0.00e+00	1169.00
IUUC-Gmo-038694	Gadus morhua	73.66	0.00e+00	912.00
IUUC-Gga-040826	Gallus gallus	91.09	0.00e+00	1177.00
IUUC-Gac-042125	Gasterosteus aculeatus	75.23	0.00e+00	976.00
IUUC-Ggo-045254	Gorilla gorilla	97.23	0.00e+00	1229.00
IUUC-Hsa-046722	Homo sapiens	97.08	0.00e+00	1229.00
IUUC-Itr-048149	Ictidomys tridecemlineatus	97.70	1.00e-101	361.00
IUUC-Lch-050312	Latimeria chalumnae	80.34	0.00e+00	682.00
IUUC-Loc-051990	Lepisosteus oculatus	80.64	0.00e+00	969.00
IUUC-Laf-054375	Loxodonta africana	98.14	0.00e+00	728.00
IUUC-Mcc-054627	Macaca mulatta	96.86	0.00e+00	1196.00
IUUC-Meu-056611	Macropus eugenii	71.72	4.00e-134	471.00
IUUC-Mga-059400	Meleagris gallopavo	88.79	0.00e+00	1151.00
IUUC-Mmr-060882	Microcebus murinus	98.61	0.00e+00	1207.00
IUUC-Mdo-061874	Monodelphis domestica	91.38	0.00e+00	1188.00
IUUC-Mmu-063444	Mus musculus	95.99	0.00e+00	1214.00
IUUC-Mpu-065713	Mustela putorius furo	96.21	0.00e+00	1183.00
IUUC-Mlu-068122	Myotis lucifugus	95.79	0.00e+00	1160.00
IUUC-Nle-069025	Nomascus leucogenys	96.77	0.00e+00	1217.00
IUUC-Opr-071089	Ochotona princeps	86.44	0.00e+00	1094.00
IUUC-Ont-072421	Oreochromis niloticus	74.70	0.00e+00	957.00
IUUC-Oan-073092	Ornithorhynchus anatinus	87.65	0.00e+00	865.00
IUUC-Ola-086497	Oryzias latipes	75.71	0.00e+00	971.00
IUUC-Oar-090120	Ovis aries	97.23	0.00e+00	1203.00
IUUC-Ptr-091554	Pan troglodytes	97.23	0.00e+00	1229.00
IUUC-Pan-091985	Papio anubis	97.23	0.00e+00	1204.00
IUUC-Psi-093548	Pelodiscus sinensis	90.88	0.00e+00	1107.00
IUUC-Pma-094123	Petromyzon marinus	51.47	6.00e-54	203.00
IUUC-Pfo-096729	Poecilia formosa	74.33	0.00e+00	959.00
IUUC-Pab-097810	Pongo abelii	97.38	0.00e+00	1231.00
IUUC-Pca-101079	Procavia capensis	89.18	0.00e+00	899.00
IUUC-Pva-102534	Pteropus vampyrus	88.13	0.00e+00	922.00
IUUC-Rno-105127	Rattus norvegicus	94.94	0.00e+00	1098.00
IUUC-Sha-106667	Sarcophilus harrisii	92.74	0.00e+00	1043.00
IUUC-Ssl-108656	Sclerotinia sclerotiorum	23.88	3.10e-02	32.00
IUUC-Sar-113424	Sorex araneus	83.06	0.00e+00	654.00
IUUC-Ssc-115974	Sus scrofa	96.22	0.00e+00	1169.00
IUUC-Tgu-116495	Taeniopygia guttata	90.78	0.00e+00	1171.00
IUUC-Tru-118727	Takifugu rubripes	72.90	0.00e+00	939.00
IUUC-Tsy-118906	Tarsius syrichta	92.14	0.00e+00	1108.00
IUUC-Tni-119717	Tetraodon nigroviridis	76.07	0.00e+00	961.00
IUUC-Tbe-127849	Tupaia belangeri	83.30	0.00e+00	727.00
IUUC-Ttr-128660	Tursiops truncatus	92.48	0.00e+00	1157.00
IUUC-Vpa-130359	Vicugna pacos	96.54	0.00e+00	1191.00
IUUC-Xtr-132212	Xenopus tropicalis	82.95	0.00e+00	723.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence