iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-034244

Ensembl Protein ID

ENSECAP00000002300.1

UniProt Accession

F6YSR6; F6YSR6_HORSE

Protein Name

Inhibitor of growth protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000003357.1	ENSECAT00000003228.1	ENSECAP00000002300.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	3.80e-09	36.8	166	213

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C + + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr 
   Q: 166  TYC-LCNQVSYGE--MIGCDNdeCPiEWFHFSCVGLN---HKPKGK-WYCPKCRG 213
           69*.*******99..******9**99***********...999997.******85 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

EILKELDDYY EKFKRETDGT QKRRVLHCIQ RALIRSQELG DEKIQIVSQM VELVENRTRQ 60
VDSHVELFEA HQEVSDTTGH SGKAGQDKSK NETITQAEKP NNKRSRRQRN NENRENAANN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCAGAAATCC TGAAGGAGCT AGATGACTAT TATGAGAAGT TTAAACGTGA GACGGATGGC 60
ACCCAGAAGA GGCGAGTGCT GCACTGCATT CAGAGAGCCC TGATTCGGAG CCAGGAGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028643--ING1
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006606--P:protein import into nucleus
GO:0010941--P:regulation of cell death

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001945	Ailuropoda melanoleuca	97.01	8.00e-106	376.00
IUUC-Apl-003910	Anas platyrhynchos	93.56	1.00e-101	362.00
IUUC-Aca-004874	Anolis carolinensis	93.16	4.00e-101	360.00
IUUC-Ame-011262	Astyanax mexicanus	66.53	2.00e-75	275.00
IUUC-Bta-013507	Bos taurus	91.03	1.00e-93	335.00
IUUC-Cja-018925	Callithrix jacchus	88.46	5.00e-97	347.00
IUUC-Cfa-020947	Canis familiaris	96.58	1.00e-104	372.00
IUUC-Cpo-022286	Cavia porcellus	93.16	1.00e-101	362.00
IUUC-Csa-023825	Chlorocebus sabaeus	88.03	1.00e-96	345.00
IUUC-Cho-024577	Choloepus hoffmanni	95.71	4.00e-104	370.00
IUUC-Cne-027005	Cryptococcus neoformans	47.76	8.00e-16	77.80
IUUC-Dno-029834	Dasypus novemcinctus	94.87	1.00e-104	372.00
IUUC-Dor-030315	Dipodomys ordii	90.60	4.00e-104	371.00
IUUC-Ete-032408	Echinops telfairi	92.70	7.00e-98	350.00
IUUC-Fca-035391	Felis catus	94.95	5.00e-96	343.00
IUUC-Fal-036838	Ficedula albicollis	92.74	4.00e-101	360.00
IUUC-Gga-040619	Gallus gallus	92.31	9.00e-101	359.00
IUUC-Gac-041996	Gasterosteus aculeatus	62.71	1.00e-71	263.00
IUUC-Ggo-045481	Gorilla gorilla	87.61	3.00e-96	345.00
IUUC-Hsa-046170	Homo sapiens	87.61	3.00e-96	345.00
IUUC-Itr-048440	Ictidomys tridecemlineatus	95.73	2.00e-105	374.00
IUUC-Lch-050397	Latimeria chalumnae	86.75	2.00e-95	341.00
IUUC-Loc-052038	Lepisosteus oculatus	80.82	2.00e-80	291.00
IUUC-Laf-054126	Loxodonta africana	96.58	5.00e-107	380.00
IUUC-Mcc-055031	Macaca mulatta	87.61	4.00e-96	344.00
IUUC-Meu-056248	Macropus eugenii	93.99	7.00e-101	360.00
IUUC-Mga-059217	Meleagris gallopavo	92.27	9.00e-100	355.00
IUUC-Mmr-061581	Microcebus murinus	95.73	1.00e-105	375.00
IUUC-Mdo-062452	Monodelphis domestica	93.59	5.00e-102	363.00
IUUC-Mmu-063412	Mus musculus	94.44	4.00e-104	370.00
IUUC-Mpu-066479	Mustela putorius furo	97.01	1.00e-105	375.00
IUUC-Mlu-067723	Myotis lucifugus	97.01	5.00e-106	376.00
IUUC-Nle-069122	Nomascus leucogenys	87.61	5.00e-96	343.00
IUUC-Opr-070835	Ochotona princeps	85.41	7.00e-85	306.00
IUUC-Ont-071606	Oreochromis niloticus	92.50	4.00e-45	174.00
IUUC-Oan-073023	Ornithorhynchus anatinus	91.03	3.00e-98	351.00
IUUC-Ocu-073779	Oryctolagus cuniculus	91.45	3.00e-96	344.00
IUUC-Ola-086891	Oryzias latipes	64.10	7.00e-72	263.00
IUUC-Oga-087954	Otolemur garnettii	93.59	4.00e-103	367.00
IUUC-Oar-090006	Ovis aries	91.45	2.00e-99	355.00
IUUC-Ptr-090589	Pan troglodytes	88.03	1.00e-96	345.00
IUUC-Pan-091896	Papio anubis	87.61	2.00e-96	345.00
IUUC-Psi-093266	Pelodiscus sinensis	93.16	1.00e-101	362.00
IUUC-Pma-094265	Petromyzon marinus	75.34	2.00e-33	134.00
IUUC-Pfo-097531	Poecilia formosa	59.85	4.00e-70	258.00
IUUC-Pab-098253	Pongo abelii	88.03	2.00e-96	345.00
IUUC-Pva-102753	Pteropus vampyrus	93.16	3.00e-94	338.00
IUUC-Rno-105964	Rattus norvegicus	93.59	7.00e-93	332.00
IUUC-Sha-107270	Sarcophilus harrisii	92.74	2.00e-100	358.00
IUUC-Tgu-116822	Taeniopygia guttata	93.16	2.00e-101	362.00
IUUC-Tni-119980	Tetraodon nigroviridis	58.85	3.00e-70	258.00
IUUC-Tvi-122341	Trichoderma virens	62.50	4.00e-16	77.00
IUUC-Ttr-128672	Tursiops truncatus	95.30	3.00e-103	367.00
IUUC-Xtr-132200	Xenopus tropicalis	83.33	3.00e-88	317.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence