iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004591

Ensembl Protein ID

ENSACAP00000006192.3

UniProt Accession

G1KF97; G1KF97_ANOCA

Protein Name

Uncharacterized protein

Gene Name

ARHGEF7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000006216.3	ENSACAT00000006329.3	ENSACAP00000006192.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.00e-15	55.9	166	221

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            +v++ ++++ +n+deL+++kGd+++v     +++gW++g  + +gk G fP+n+v++++
   Q: 166  MVVRAKFNFQQTNEDELSFTKGDIIHVT--RVEEGGWWEG--TYNGKTGWFPSNYVREVK 221
           57999**********************7..999*******..8**************997 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MNSAEQTVTW LITLGVLESP KKSISDPEGF LQASLKDGVV LCRLLDRLLP GTIDKVYPEP 60
RTEAECLSNI REFLRACGAT LRLETFDAND LYQGQNFNKV LSSLVALNKV TADIGLGSDS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCTTCGCCA AGGAAAGGGT GGCGGCTTTT ATGCGGGGGC TCCTGGAGGA AAGGGGAGGG 60
GGTCTGAGCC TCCTCCTCCT CCTCCTCTCC CCCTCCCCTC CCCTCCCTCA ATGATGTCAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-1185--Reference proteome

Interpro

IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR032409--GEF_CC
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50021--CH
PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF16523--betaPIX_CC
PF00307--CH
PF00169--PH
PF00621--RhoGEF
PF07653--SH3_2

PRINTS

PR00452--SH3DOMAIN

SMART

SM00033--CH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0005925--C:focal adhesion
GO:0030027--C:lamellipodium
GO:0043005--C:neuron projection
GO:0043025--C:neuronal cell body
GO:0005886--C:plasma membrane
GO:0043234--C:protein complex
GO:0000322--C:storage vacuole
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0048041--P:focal adhesion assembly
GO:0007030--P:Golgi organization
GO:0002244--P:hematopoietic progenitor cell differentiation
GO:0035556--P:intracellular signal transduction
GO:0030032--P:lamellipodium assembly
GO:0043065--P:positive regulation of apoptotic process
GO:0010763--P:positive regulation of fibroblast migration
GO:0060124--P:positive regulation of growth hormone secretion
GO:2000394--P:positive regulation of lamellipodium morphogenesis
GO:0032092--P:positive regulation of protein binding
GO:1900026--P:positive regulation of substrate adhesion-dependent cell spreading
GO:1904424--P:regulation of GTP binding
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001259	Ailuropoda melanoleuca	88.54	0.00e+00	1265.00
IUUC-Ame-010759	Astyanax mexicanus	75.12	0.00e+00	1275.00
IUUC-Bgr-012305	Blumeria graminis	42.86	3.00e-11	64.30
IUUC-Bta-013328	Bos taurus	89.79	0.00e+00	1459.00
IUUC-Bci-013864	Botrytis cinerea	47.46	8.00e-12	66.20
IUUC-Cja-018742	Callithrix jacchus	91.17	0.00e+00	1150.00
IUUC-Cfa-020756	Canis familiaris	90.35	0.00e+00	1101.00
IUUC-Cpo-021284	Cavia porcellus	89.57	0.00e+00	1375.00
IUUC-Csa-023162	Chlorocebus sabaeus	92.34	0.00e+00	1492.00
IUUC-Cho-024736	Choloepus hoffmanni	73.86	4.00e-174	604.00
IUUC-Cin-025535	Ciona intestinalis	41.10	1.00e-94	340.00
IUUC-Cgl-026676	Colletotrichum gloeosporioides	42.86	6.00e-12	66.60
IUUC-Dre-028646	Danio rerio	75.69	0.00e+00	1273.00
IUUC-Dno-029461	Dasypus novemcinctus	93.62	0.00e+00	1503.00
IUUC-Dor-030623	Dipodomys ordii	80.33	0.00e+00	1035.00
IUUC-Dme-032219	Drosophila melanogaster	45.34	3.00e-103	370.00
IUUC-Ete-032236	Echinops telfairi	79.02	0.00e+00	795.00
IUUC-Eca-034137	Equus caballus	92.55	0.00e+00	1320.00
IUUC-Fca-035742	Felis catus	88.72	0.00e+00	1071.00
IUUC-Fal-037205	Ficedula albicollis	95.32	0.00e+00	1217.00
IUUC-Fox-037757	Fusarium oxysporum	38.89	2.00e-11	65.50
IUUC-Fso-038433	Fusarium solani	40.28	4.00e-12	67.00
IUUC-Gmo-039475	Gadus morhua	69.18	0.00e+00	1079.00
IUUC-Gga-040539	Gallus gallus	93.87	0.00e+00	995.00
IUUC-Gac-042615	Gasterosteus aculeatus	65.25	0.00e+00	979.00
IUUC-Ggo-044470	Gorilla gorilla	86.69	0.00e+00	1249.00
IUUC-Hsa-046398	Homo sapiens	89.52	0.00e+00	1304.00
IUUC-Loc-052146	Lepisosteus oculatus	86.67	0.00e+00	1408.00
IUUC-Laf-053891	Loxodonta africana	89.33	0.00e+00	1438.00
IUUC-Mcc-055483	Macaca mulatta	89.14	0.00e+00	1298.00
IUUC-Mga-059410	Meleagris gallopavo	93.73	0.00e+00	1370.00
IUUC-Mmr-060758	Microcebus murinus	91.83	0.00e+00	1266.00
IUUC-Mdo-061900	Monodelphis domestica	80.74	0.00e+00	1290.00
IUUC-Mmu-063849	Mus musculus	90.53	0.00e+00	1259.00
IUUC-Mpu-065876	Mustela putorius furo	90.02	0.00e+00	1091.00
IUUC-Mlu-067970	Myotis lucifugus	93.32	0.00e+00	1333.00
IUUC-Nle-069685	Nomascus leucogenys	73.05	0.00e+00	985.00
IUUC-Opr-071132	Ochotona princeps	60.70	0.00e+00	670.00
IUUC-Ont-071815	Oreochromis niloticus	76.16	0.00e+00	1269.00
IUUC-Oan-073057	Ornithorhynchus anatinus	93.48	0.00e+00	1218.00
IUUC-Ola-086663	Oryzias latipes	73.46	0.00e+00	1090.00
IUUC-Oga-088103	Otolemur garnettii	90.56	0.00e+00	1262.00
IUUC-Ptr-091162	Pan troglodytes	88.65	0.00e+00	1196.00
IUUC-Pan-092093	Papio anubis	83.64	0.00e+00	1357.00
IUUC-Pma-094701	Petromyzon marinus	62.98	7.00e-134	470.00
IUUC-Pfo-096736	Poecilia formosa	69.06	0.00e+00	1102.00
IUUC-Pab-097641	Pongo abelii	91.01	0.00e+00	1258.00
IUUC-Pva-102819	Pteropus vampyrus	89.49	0.00e+00	1251.00
IUUC-Pte-104123	Pyrenophora teres	46.43	9.00e-11	62.80
IUUC-Pyt-104567	Pyrenophora triticirepentis	46.43	8.00e-11	62.80
IUUC-Rno-106099	Rattus norvegicus	91.07	0.00e+00	1427.00
IUUC-Sha-106845	Sarcophilus harrisii	79.03	0.00e+00	1125.00
IUUC-Ssl-108538	Sclerotinia sclerotiorum	45.76	5.00e-11	63.50
IUUC-Ssc-116036	Sus scrofa	89.68	0.00e+00	1072.00
IUUC-Tgu-117498	Taeniopygia guttata	91.88	0.00e+00	1457.00
IUUC-Tru-118278	Takifugu rubripes	73.12	0.00e+00	1092.00
IUUC-Tsy-118990	Tarsius syrichta	89.21	0.00e+00	929.00
IUUC-Tni-120852	Tetraodon nigroviridis	74.37	0.00e+00	1006.00
IUUC-Tre-121917	Trichoderma reesei	45.61	7.00e-12	66.60
IUUC-Tvi-122534	Trichoderma virens	45.61	8.00e-12	66.20
IUUC-Ttr-128922	Tursiops truncatus	84.38	0.00e+00	1089.00
IUUC-Vpa-130144	Vicugna pacos	48.03	0.00e+00	696.00
IUUC-Xtr-132012	Xenopus tropicalis	86.10	0.00e+00	1276.00
IUUC-Xma-133901	Xiphophorus maculatus	65.51	0.00e+00	1047.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence