iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tca-121737

Ensembl Protein ID

EOY06821

UniProt Accession

A0A061EPQ1; A0A061EPQ1_THECC

Genbank Protein ID

EOY06821.1

Protein Name

Ubiquitin protein ligase 6 isoform 2

Genbank Nucleotide ID

CM001882

Gene Name

TCM_021434

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TCM_021434	EOY06820	EOY06820
TCM_021434	EOY06824	EOY06824
TCM_021434	EOY06821	EOY06821

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	5.90e-108	362.2	696	1036

Active Site

Position(s)	Description	Evidence
1004	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsks 95
           ++dl+  ++v+fv+     E+g+d gG++++f+++++++ ++ ++glf  +e+ ++ l+pnp sg+ +++hl++++flG+ll+ka+++g l+d+p++++
   Q: 696  EEDLRGLIRVTFVNefgveEAGIDGGGIFKDFMENITRAAFDVQYGLF--KETADHLLYPNPGSGMIHEQHLQFYHFLGTLLAKAMFEGILVDIPFATF 792
           678999999*****9999999***************************..5566889999999999999****************************** PP
   S: 96   fyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafr 194
           f+++l +k   l+dl+++dpely++l ++k++   + + +gl+l f + ++++ge++e+eL+pgG+ni+VtneN   +++lv ++rl+ +i++q  +f 
   Q: 793  FLSKLKQKYNYLNDLPSLDPELYRHLIFLKHY---KGDIAGLELYFVIVNNEYGEQTEDELLPGGKNIRVTNENVITFIHLVSNHRLNFQIRQQSSHFL 888
           ********9999********************...55666689999999************************************************** PP
   S: 195  eGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelkprlfvirk. 291
           +Gf+++i+++++++F+e+el+lli+G+ e++dv+dl+++t+y ggy++++ +i+ Fwevl++fs e++k+fL+FvTg+sr Pl Gf++l+p lf+i++ 
   Q: 889  RGFQQLIQKDWIDMFNEHELQLLISGSlESLDVDDLRRNTNYAGGYHSEHYVIDVFWEVLKSFSLENQKKFLKFVTGCSRGPLLGFKYLEP-LFCIQRa 986
           ******************************************************************************************5.5999999 PP
   S: 292  .....dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
                +++ drlP+s TC+n+LkLP+Y ske+l+ kLlyAi+  +gF+ls
   Q: 987  agtasEEALDRLPTSATCMNLLKLPPYRSKEQLETKLLYAINADAGFDLS 1036
           **9855555**************************************985 PP

Organism

Theobroma cacao

Protein Sequence
(Fasta)

MFFSGDPTTR KRVDLGGRSS KERDRQKLLE QTRLERNRRL WLRQQNSAAL KIQKYFRGRK 60
VVEAEHAKVR EQFYQTYGKH CQNVDRHCFG PDSEFLRQLI FFFNAGNTDD FLVLVETCRL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AACTTTCCCA CTTCACAGTA CAAGGAATTA TAGCGCGAGA AAATTCTCCC AACTCCTCTA 60
GCTTCCTCTT TAGTCCTTGC TTTATTCATT TCTCCAATTT TCTCTCCATC CAAACACCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000469	Aegilops tauschii	57.51	0.00e+00	1027.00
IUUC-Atr-002669	Amborella trichopoda	63.75	0.00e+00	1285.00
IUUC-Apl-003731	Anas platyrhynchos	42.06	5.00e-108	385.00
IUUC-Aca-005248	Anolis carolinensis	38.88	1.00e-107	383.00
IUUC-Aly-005768	Arabidopsis lyrata	74.45	0.00e+00	1578.00
IUUC-Ath-006576	Arabidopsis thaliana	74.23	0.00e+00	1586.00
IUUC-Ame-010769	Astyanax mexicanus	40.52	7.00e-74	271.00
IUUC-Bta-012841	Bos taurus	41.03	2.00e-106	379.00
IUUC-Bci-013743	Botrytis cinerea	38.45	3.00e-85	309.00
IUUC-Bdi-014123	Brachypodium distachyon	60.64	0.00e+00	1181.00
IUUC-Bol-015467	Brassica oleracea	73.29	0.00e+00	1525.00
IUUC-Bra-017723	Brassica rapa	72.88	0.00e+00	1522.00
IUUC-Cfa-021031	Canis familiaris	41.44	4.00e-104	372.00
IUUC-Cre-022725	Chlamydomonas reinhardtii	45.78	6.00e-99	353.00
IUUC-Cho-024750	Choloepus hoffmanni	47.95	5.00e-91	328.00
IUUC-Cme-027265	Cyanidioschyzon merolae	39.86	3.00e-104	372.00
IUUC-Ete-033041	Echinops telfairi	43.38	1.00e-67	250.00
IUUC-Fal-037389	Ficedula albicollis	41.86	1.00e-107	384.00
IUUC-Gga-040310	Gallus gallus	41.86	5.00e-107	382.00
IUUC-Gma-042786	Glycine max	75.58	0.00e+00	1537.00
IUUC-Hvu-047770	Hordeum vulgare	64.07	0.00e+00	1001.00
IUUC-Itr-048372	Ictidomys tridecemlineatus	46.23	4.00e-94	337.00
IUUC-Kpa-049307	Komagataella pastoris	36.32	8.00e-70	258.00
IUUC-Lpe-051428	Leersia perrieri	56.12	0.00e+00	1110.00
IUUC-Loc-052218	Lepisosteus oculatus	46.53	9.00e-104	370.00
IUUC-Mtr-058154	Medicago truncatula	74.03	0.00e+00	1531.00
IUUC-Mla-059124	Melampsora laricipopulina	45.54	1.00e-95	342.00
IUUC-Mga-059581	Meleagris gallopavo	41.86	3.00e-107	382.00
IUUC-Mvi-060445	Microbotryum violaceum	37.42	3.00e-100	359.00
IUUC-Mdo-062194	Monodelphis domestica	41.86	6.00e-106	378.00
IUUC-Mac-065275	Musa acuminata	62.69	0.00e+00	1088.00
IUUC-Mpu-066439	Mustela putorius furo	40.63	3.00e-105	375.00
IUUC-Mlu-068228	Myotis lucifugus	41.03	2.00e-106	380.00
IUUC-Oan-072800	Ornithorhynchus anatinus	39.24	3.00e-107	382.00
IUUC-Oba-075006	Oryza barthii	61.37	0.00e+00	1255.00
IUUC-Obr-076133	Oryza brachyantha	61.18	0.00e+00	1250.00
IUUC-Ogl-077003	Oryza glaberrima	61.37	0.00e+00	1254.00
IUUC-Ogu-078947	Oryza glumaepatula	61.60	0.00e+00	1252.00
IUUC-Oin-079407	Oryza indica	59.54	0.00e+00	1195.00
IUUC-Olo-080475	Oryza longistaminata	61.46	0.00e+00	1258.00
IUUC-Ome-081342	Oryza meridionalis	59.63	0.00e+00	1192.00
IUUC-Oni-082385	Oryza nivara	61.60	0.00e+00	1253.00
IUUC-Opu-083176	Oryza punctata	60.46	0.00e+00	1220.00
IUUC-Oru-084554	Oryza rufipogon	59.69	0.00e+00	1200.00
IUUC-Osa-085355	Oryza sativa	61.66	0.00e+00	1259.00
IUUC-Olu-087699	Ostreococcus lucimarinus	47.09	8.00e-100	356.00
IUUC-Oar-089441	Ovis aries	41.03	1.00e-106	380.00
IUUC-Pno-095132	Phaeosphaeria nodorum	38.17	1.00e-62	234.00
IUUC-Ppa-095682	Physcomitrella patens	51.33	0.00e+00	951.00
IUUC-Pop-098928	Populus trichocarpa	78.98	0.00e+00	1639.00
IUUC-Pca-100987	Procavia capensis	48.34	2.00e-97	350.00
IUUC-Ppe-102040	Prunus persica	79.83	0.00e+00	1644.00
IUUC-Pgr-103513	Puccinia graminis	45.05	2.00e-95	343.00
IUUC-Ptt-103967	Puccinia triticina	43.07	2.00e-85	310.00
IUUC-Pte-104105	Pyrenophora teres	40.13	1.00e-83	304.00
IUUC-Pyt-104449	Pyrenophora triticirepentis	40.13	2.00e-83	303.00
IUUC-Sja-107889	Schizosaccharomyces japonicus	38.47	1.00e-101	363.00
IUUC-Spo-108097	Schizosaccharomyces pombe	37.74	2.00e-99	356.00
IUUC-Smo-109007	Selaginella moellendorffii	46.63	0.00e+00	910.00
IUUC-Sit-110457	Setaria italica	61.62	0.00e+00	1250.00
IUUC-Sly-111362	Solanum lycopersicum	73.84	0.00e+00	1547.00
IUUC-Sar-113687	Sorex araneus	43.32	8.00e-61	228.00
IUUC-Sbi-113882	Sorghum bicolor	61.23	0.00e+00	1235.00
IUUC-Tgu-116729	Taeniopygia guttata	41.65	2.00e-106	379.00
IUUC-Tru-118068	Takifugu rubripes	47.77	3.00e-106	379.00
IUUC-Tsy-118942	Tarsius syrichta	49.43	8.00e-69	254.00
IUUC-Tni-120732	Tetraodon nigroviridis	46.29	1.00e-99	357.00
IUUC-Tae-125229	Triticum aestivum	62.02	0.00e+00	1271.00
IUUC-Tme-127102	Tuber melanosporum	39.83	1.00e-84	308.00
IUUC-Tbe-127351	Tupaia belangeri	45.77	2.00e-86	313.00
IUUC-Vvi-131234	Vitis vinifera	79.05	0.00e+00	1663.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence