iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ola-087337

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

BAAF04020975

Gene Name

ube3b

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSORLG00000007463.1	ENSORLT00000009359.1	ENSORLP00000009358.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	3.60e-112	375.4	705	1068

Active Site

Position(s)	Description	Evidence
1036	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdg 85
           ++k +++v+fv+     E+g+d++Gv++efl++++k+++np l+lf+++++d++ l+p+p+s++++ +hl lFef+G++lgka+++g
   Q: 705  SIKGVIRVKFVNdlgvdEAGIDQDGVFKEFLEEIIKKVFNPALNLFKTTSGDER-LYPSPTSYIHE-NHLLLFEFVGKMLGKAIYEG 789
           578899****************************************99987665.59*******76.******************** PP
   S: 86   rlldlplsksfyklllgk.....klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtn 167
            ++d+p++++f++++lg+       s+++l+++d+e+yk+l++ik++ + d+ +lgl+l++  +e+++g+  ++eL+pgG++ipVtn
   Q: 790  IVVDVPFASFFLSQVLGHhhssfYSSIDELPSLDSEFYKNLTSIKRY-DGDVGDLGLTLSY--DEDVMGQLVCHELIPGGKTIPVTN 873
           ******************777776999********************.7899998777776..5999******************** PP
   S: 168  eNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevl 253
           eNk +Y++l++++r++++ikeq++af +Gf+ +i++e+l +F++ e++ l++G+ +eid++dlkk+t y gg+++++++i+w+w++l
   Q: 874  ENKISYIHLMAHFRMHTQIKEQTAAFIRGFRCIINPEWLHMFSTPEVQRLVSGDnAEIDLDDLKKHTVYYGGFHSSHRVIIWLWDIL 960
           ******************************************************9******************************** PP
   S: 254  .eefsseerkafLqFvTgssrlPlgGfaelk........................prlfvirkdasddrlPssnTCfnyLkLPeYss 315
            ++f++eer++fL+FvT++sr Pl Gfa+lk                        + +f+irk++   rlP+s+TCfn+LkLP+Ys+
   Q: 961  sSDFNAEERAMFLKFVTSCSRPPLLGFAYLKppfsircvevsddqdtgdtlgsvlRGFFTIRKKEPGGRLPTSSTCFNLLKLPNYSK 1047
           999************************************************************9999******************** PP
   S: 316  keilkekLlyAieetkgFels 336
           k+il++kL+yAi++++gFels
   Q: 1048 KSILRDKLRYAISMNTGFELS 1068
           ******************985 PP

Organism

Oryzias latipes

Protein Sequence
(Fasta)

MFGVPQSSKS EFLDKARQAR EERKGQKEKE KAATQIQALI RRFLCRCRLQ KELRKEVDDY 60
FQTSETGATK RNALSIFKIA RKLLFIFCQE DKMRFEKLCR AILASMEVEN EPKVWYVSLA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTTGGTG TGCCTCAAAG CTCCAAGTCT GAGTTCCTGG ACAAAGCCAG GCAGGCCAGA 60
GAAGAAAGGA AAGGGCAAAA GGAGAAAGAA AAAGCAGCAA CCCAAATTCA AGCTCTAATA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS
IPR027401--Myosin-like_IQ_dom

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT

SMART

SM00119--HECTc
SM00015--IQ

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

ola:101170594

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	40.21	1.00e-106	381.00
IUUC-Aml-002107	Ailuropoda melanoleuca	81.01	0.00e+00	1781.00
IUUC-Atr-003017	Amborella trichopoda	40.07	2.00e-113	404.00
IUUC-Apl-003328	Anas platyrhynchos	84.41	0.00e+00	1772.00
IUUC-Aly-005794	Arabidopsis lyrata	39.64	3.00e-108	386.00
IUUC-Ath-007269	Arabidopsis thaliana	40.00	3.00e-111	396.00
IUUC-Bta-013547	Bos taurus	81.20	0.00e+00	1808.00
IUUC-Bdi-014502	Brachypodium distachyon	40.21	1.00e-111	397.00
IUUC-Bol-015093	Brassica oleracea	40.53	2.00e-112	400.00
IUUC-Bra-016722	Brassica rapa	40.71	2.00e-113	404.00
IUUC-Cel-018447	Caenorhabditis elegans	39.22	0.00e+00	682.00
IUUC-Cja-019855	Callithrix jacchus	80.92	0.00e+00	1779.00
IUUC-Cfa-020066	Canis familiaris	81.29	0.00e+00	1766.00
IUUC-Cpo-021504	Cavia porcellus	81.29	0.00e+00	1820.00
IUUC-Csa-023579	Chlorocebus sabaeus	80.92	0.00e+00	1781.00
IUUC-Cho-024430	Choloepus hoffmanni	70.65	0.00e+00	1281.00
IUUC-Cin-025750	Ciona intestinalis	45.68	0.00e+00	947.00
IUUC-Csv-026016	Ciona savignyi	47.00	0.00e+00	1005.00
IUUC-Dre-028271	Danio rerio	90.74	0.00e+00	1930.00
IUUC-Dno-029054	Dasypus novemcinctus	81.67	0.00e+00	1798.00
IUUC-Dor-030938	Dipodomys ordii	85.62	0.00e+00	1101.00
IUUC-Dme-031602	Drosophila melanogaster	47.87	0.00e+00	959.00
IUUC-Ete-033041	Echinops telfairi	65.42	0.00e+00	1173.00
IUUC-Eca-034411	Equus caballus	81.38	0.00e+00	1769.00
IUUC-Eeu-035201	Erinaceus europaeus	76.51	0.00e+00	742.00
IUUC-Fca-036594	Felis catus	80.17	0.00e+00	1749.00
IUUC-Fal-037317	Ficedula albicollis	81.26	0.00e+00	1801.00
IUUC-Gmo-039412	Gadus morhua	90.51	0.00e+00	1969.00
IUUC-Gga-040149	Gallus gallus	84.67	0.00e+00	1826.00
IUUC-Gac-042088	Gasterosteus aculeatus	94.02	0.00e+00	2051.00
IUUC-Gma-043839	Glycine max	40.85	4.00e-112	399.00
IUUC-Ggo-045279	Gorilla gorilla	80.92	0.00e+00	1781.00
IUUC-Hsa-045660	Homo sapiens	80.73	0.00e+00	1774.00
IUUC-Hvu-047770	Hordeum vulgare	37.38	2.00e-108	386.00
IUUC-Itr-048372	Ictidomys tridecemlineatus	91.11	0.00e+00	803.00
IUUC-Lch-050664	Latimeria chalumnae	86.18	0.00e+00	1894.00
IUUC-Lpe-051428	Leersia perrieri	34.66	2.00e-98	353.00
IUUC-Loc-052791	Lepisosteus oculatus	91.33	0.00e+00	1937.00
IUUC-Laf-053902	Loxodonta africana	81.57	0.00e+00	1797.00
IUUC-Mcc-054730	Macaca mulatta	80.82	0.00e+00	1780.00
IUUC-Meu-056527	Macropus eugenii	76.77	0.00e+00	1627.00
IUUC-Mtr-057671	Medicago truncatula	40.50	3.00e-112	399.00
IUUC-Mga-059260	Meleagris gallopavo	84.51	0.00e+00	1825.00
IUUC-Mmr-060804	Microcebus murinus	80.26	0.00e+00	1742.00
IUUC-Mdo-062575	Monodelphis domestica	80.30	0.00e+00	1727.00
IUUC-Mmu-063636	Mus musculus	79.93	0.00e+00	1713.00
IUUC-Mac-064989	Musa acuminata	40.25	5.00e-110	392.00
IUUC-Mpu-066677	Mustela putorius furo	79.92	0.00e+00	1658.00
IUUC-Mlu-067952	Myotis lucifugus	81.38	0.00e+00	1727.00
IUUC-Nle-069153	Nomascus leucogenys	80.92	0.00e+00	1779.00
IUUC-Opr-070554	Ochotona princeps	81.31	0.00e+00	1638.00
IUUC-Ont-071372	Oreochromis niloticus	95.69	0.00e+00	2041.00
IUUC-Oan-073327	Ornithorhynchus anatinus	69.51	0.00e+00	737.00
IUUC-Ocu-074183	Oryctolagus cuniculus	79.53	0.00e+00	1763.00
IUUC-Oba-075006	Oryza barthii	37.08	5.00e-111	395.00
IUUC-Obr-076133	Oryza brachyantha	36.46	6.00e-111	395.00
IUUC-Ogl-077003	Oryza glaberrima	36.82	4.00e-111	396.00
IUUC-Ogu-078947	Oryza glumaepatula	37.60	1.00e-111	397.00
IUUC-Oin-080058	Oryza indica	40.14	2.00e-109	390.00
IUUC-Olo-080475	Oryza longistaminata	37.50	1.00e-111	397.00
IUUC-Ome-081741	Oryza meridionalis	39.75	1.00e-102	367.00
IUUC-Oni-082385	Oryza nivara	37.33	1.00e-111	397.00
IUUC-Opu-083529	Oryza punctata	40.32	1.00e-109	391.00
IUUC-Oru-084554	Oryza rufipogon	35.28	1.00e-98	354.00
IUUC-Osa-085355	Oryza sativa	37.23	1.00e-111	397.00
IUUC-Oga-088342	Otolemur garnettii	80.19	0.00e+00	1704.00
IUUC-Oar-090234	Ovis aries	80.25	0.00e+00	1776.00
IUUC-Ptr-091661	Pan troglodytes	80.92	0.00e+00	1779.00
IUUC-Pan-092728	Papio anubis	80.65	0.00e+00	1774.00
IUUC-Psi-093251	Pelodiscus sinensis	84.21	0.00e+00	1692.00
IUUC-Pma-094195	Petromyzon marinus	70.12	0.00e+00	1461.00
IUUC-Ppa-095544	Physcomitrella patens	38.36	2.00e-112	400.00
IUUC-Pfo-097472	Poecilia formosa	96.16	0.00e+00	2059.00
IUUC-Pab-098570	Pongo abelii	81.10	0.00e+00	1781.00
IUUC-Pca-100110	Procavia capensis	71.28	0.00e+00	1498.00
IUUC-Ppe-101281	Prunus persica	39.54	7.00e-107	382.00
IUUC-Pva-102887	Pteropus vampyrus	76.26	0.00e+00	1644.00
IUUC-Rno-106028	Rattus norvegicus	77.24	0.00e+00	1635.00
IUUC-Sha-107331	Sarcophilus harrisii	81.06	0.00e+00	1751.00
IUUC-Smo-109488	Selaginella moellendorffii	38.15	2.00e-107	384.00
IUUC-Sit-109811	Setaria italica	39.79	2.00e-109	390.00
IUUC-Sar-113287	Sorex araneus	68.23	9.00e-160	557.00
IUUC-Sbi-114433	Sorghum bicolor	40.46	2.00e-110	394.00
IUUC-Ssc-116103	Sus scrofa	81.67	0.00e+00	1773.00
IUUC-Tgu-117275	Taeniopygia guttata	83.83	0.00e+00	1806.00
IUUC-Tru-118681	Takifugu rubripes	93.82	0.00e+00	2050.00
IUUC-Tsy-118985	Tarsius syrichta	71.08	0.00e+00	825.00
IUUC-Tni-120850	Tetraodon nigroviridis	97.99	0.00e+00	818.00
IUUC-Tca-121770	Theobroma cacao	39.54	5.00e-111	395.00
IUUC-Tae-125466	Triticum aestivum	36.51	3.00e-108	386.00
IUUC-Tur-126086	Triticum urartu	40.14	5.00e-106	379.00
IUUC-Tbe-127461	Tupaia belangeri	77.17	0.00e+00	1627.00
IUUC-Ttr-129269	Tursiops truncatus	81.01	0.00e+00	1747.00
IUUC-Vpa-130523	Vicugna pacos	71.85	2.00e-111	397.00
IUUC-Vvi-131524	Vitis vinifera	39.50	6.00e-109	389.00
IUUC-Xtr-132146	Xenopus tropicalis	82.28	0.00e+00	1821.00
IUUC-Xma-133526	Xiphophorus maculatus	95.97	0.00e+00	2052.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence