iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-067026

Ensembl Protein ID

ENSMLUP00000001147.2

UniProt Accession

G1NV64; G1NV64_MYOLU

Genbank Protein ID

ENSMLUP00000001147

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02045063

Gene Name

SQSTM1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000001250.2	ENSMLUT00000001250.2	ENSMLUP00000001147.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	48.00	3.00e-08	56.20	IUUC-Dme-031659
UBD/Alpha-Helix/UBA	88.00	0.00e+00	630.00	IUUC-Hsa-046390
ULD/UDP/UFD/PB1	88.00	0.00e+00	630.00	IUUC-Hsa-046390
UBD/Alpha-Helix/UBA	85.41	3.00e-180	628.00	IUUC-Mmu-063589
UBD/Alpha-Helix/UBA	85.15	5.00e-178	620.00	IUUC-Rno-105539

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

DEDGDLVAFS SDEELTMAMA YVKDDLFRIY IKERKECRRD HRPPCAQEAP RNMVHPNVIC 60
DGCNGPVVGT RYKCSVCPDY DLCAGCEGKG MHREHSKLAF PSPFEGFPHS RWLRKLKHGH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATGAGGACG GGGACTTGGT TGCCTTTTCC AGTGACGAGG AGCTGACGAT GGCCATGGCA 60
TACGTGAAGG ATGACCTGTT CCGTATTTAC ATTAAAGGTA AGGGGCTGCC TGGGGTGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000270--PB1_dom
IPR033741--SQSTM_UBA
IPR015940--UBA
IPR009060--UBA-like
IPR000433--Znf_ZZ

PROSITE

PS51745--PB1
PS50030--UBA
PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2

Pfam

PF16577--UBA_5
PF00569--ZZ

SMART

SM00165--UBA
SM00291--ZnF_ZZ

Gene Ontology

GO:0016235--C:aggresome
GO:0044753--C:amphisome
GO:0044754--C:autolysosome
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0000932--C:P-body
GO:0016605--C:PML body
GO:0000407--C:pre-autophagosomal structure
GO:0097225--C:sperm midpiece
GO:0008270--F:zinc ion binding
GO:0006914--P:autophagy
GO:0044130--P:negative regulation of growth of symbiont in host
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0098779--P:positive regulation of macromitophagy in response to mitochondrial depolarization
GO:0043122--P:regulation of I-kappaB kinase/NF-kappaB signaling
GO:0061635--P:regulation of protein complex stability

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001367	Ailuropoda melanoleuca	84.95	6.00e-169	586.00
IUUC-Apl-003897	Anas platyrhynchos	60.05	8.00e-117	413.00
IUUC-Aca-004699	Anolis carolinensis	49.08	4.00e-88	318.00
IUUC-Ame-010982	Astyanax mexicanus	45.07	4.00e-66	245.00
IUUC-Bta-012634	Bos taurus	87.47	0.00e+00	643.00
IUUC-Cel-018540	Caenorhabditis elegans	39.06	4.00e-10	60.10
IUUC-Cja-019684	Callithrix jacchus	86.67	2.00e-176	612.00
IUUC-Cfa-020573	Canis familiaris	80.99	3.00e-135	474.00
IUUC-Cpo-021425	Cavia porcellus	78.40	1.00e-153	536.00
IUUC-Csa-023968	Chlorocebus sabaeus	86.40	4.00e-173	600.00
IUUC-Cho-024596	Choloepus hoffmanni	80.65	1.00e-51	196.00
IUUC-Cin-025557	Ciona intestinalis	25.14	6.00e-19	88.20
IUUC-Csv-025974	Ciona savignyi	57.50	6.00e-09	54.70
IUUC-Dre-028621	Danio rerio	46.00	9.00e-84	303.00
IUUC-Dno-029060	Dasypus novemcinctus	85.41	0.00e+00	637.00
IUUC-Dor-030547	Dipodomys ordii	84.95	1.00e-103	370.00
IUUC-Dme-031659	Drosophila melanogaster	48.00	5.00e-09	56.20
IUUC-Ete-033201	Echinops telfairi	77.07	3.00e-157	547.00
IUUC-Eca-033456	Equus caballus	88.19	0.00e+00	657.00
IUUC-Eeu-035157	Erinaceus europaeus	81.96	3.00e-170	591.00
IUUC-Fca-035403	Felis catus	86.67	1.00e-176	612.00
IUUC-Fal-036798	Ficedula albicollis	58.54	4.00e-121	428.00
IUUC-Gmo-039619	Gadus morhua	45.81	8.00e-43	167.00
IUUC-Gga-040137	Gallus gallus	59.85	3.00e-118	418.00
IUUC-Gac-042410	Gasterosteus aculeatus	47.88	2.00e-89	322.00
IUUC-Ggo-044690	Gorilla gorilla	88.00	6.00e-175	607.00
IUUC-Hsa-046390	Homo sapiens	88.00	1.00e-174	605.00
IUUC-Itr-048536	Ictidomys tridecemlineatus	88.53	0.00e+00	655.00
IUUC-Lch-049658	Latimeria chalumnae	48.47	6.00e-102	364.00
IUUC-Loc-052589	Lepisosteus oculatus	49.48	2.00e-98	352.00
IUUC-Laf-053746	Loxodonta africana	77.07	9.00e-157	546.00
IUUC-Mcc-055635	Macaca mulatta	85.60	3.00e-175	607.00
IUUC-Meu-056528	Macropus eugenii	50.67	3.00e-93	334.00
IUUC-Mga-059458	Meleagris gallopavo	60.10	5.00e-118	417.00
IUUC-Mvi-060347	Microbotryum violaceum	48.84	3.00e-07	51.60
IUUC-Mmr-061539	Microcebus murinus	77.38	1.00e-102	366.00
IUUC-Mdo-063083	Monodelphis domestica	62.69	2.00e-130	458.00
IUUC-Mmu-063589	Mus musculus	85.15	0.00e+00	639.00
IUUC-Mpu-065727	Mustela putorius furo	86.02	1.00e-179	621.00
IUUC-Nle-069356	Nomascus leucogenys	56.99	2.00e-90	325.00
IUUC-Opr-071091	Ochotona princeps	66.20	1.00e-79	290.00
IUUC-Ont-071864	Oreochromis niloticus	47.91	5.00e-95	341.00
IUUC-Oan-073308	Ornithorhynchus anatinus	65.73	4.00e-131	461.00
IUUC-Ocu-074110	Oryctolagus cuniculus	88.50	0.00e+00	639.00
IUUC-Ola-086944	Oryzias latipes	44.80	2.00e-38	151.00
IUUC-Oga-088869	Otolemur garnettii	87.73	0.00e+00	632.00
IUUC-Oar-089857	Ovis aries	88.00	0.00e+00	649.00
IUUC-Ptr-091640	Pan troglodytes	88.00	5.00e-175	607.00
IUUC-Pan-092831	Papio anubis	88.27	6.00e-179	620.00
IUUC-Psi-093925	Pelodiscus sinensis	57.47	3.00e-117	414.00
IUUC-Pma-094576	Petromyzon marinus	31.01	3.00e-35	142.00
IUUC-Pfo-097297	Poecilia formosa	46.63	2.00e-83	303.00
IUUC-Pab-098725	Pongo abelii	77.07	2.00e-149	521.00
IUUC-Pca-101106	Procavia capensis	85.87	2.00e-169	588.00
IUUC-Pva-102710	Pteropus vampyrus	85.45	1.00e-159	555.00
IUUC-Rno-105539	Rattus norvegicus	85.15	0.00e+00	646.00
IUUC-Sha-107469	Sarcophilus harrisii	58.44	2.00e-123	435.00
IUUC-Ssc-115526	Sus scrofa	86.93	0.00e+00	631.00
IUUC-Tgu-117194	Taeniopygia guttata	58.96	5.00e-119	421.00
IUUC-Tru-117896	Takifugu rubripes	49.74	1.00e-92	333.00
IUUC-Tni-119943	Tetraodon nigroviridis	47.16	1.00e-80	293.00
IUUC-Ttr-128676	Tursiops truncatus	88.27	0.00e+00	659.00
IUUC-Vda-129812	Verticillium dahliae	44.07	9.00e-08	52.00
IUUC-Vpa-130319	Vicugna pacos	94.00	1.00e-56	213.00
IUUC-Xtr-132907	Xenopus tropicalis	55.64	1.00e-116	413.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence