iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-065822

Ensembl Protein ID

ENSMPUP00000016474.1

UniProt Accession

M3YYR4; M3YYR4_MUSPF

Genbank Protein ID

ENSMPUP00000016474

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01085099

Gene Name

USP42

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000016577.1	ENSMPUT00000016719.1	ENSMPUP00000016474.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.40e-81	274.3	112	411

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           Gl+NlgNtC+ N++LQcL+ +p+l++++l+ ++++++++     +  ++++++q  +++ +++   +++p  +++ ++++a++f+  +q
   Q: 112  GLQNLGNTCFANAALQCLTYTPPLANYMLShEHSKTCHA-----EGFCMMCTMQAHITQALSNPGDVIKPMFVINEMRRIARHFRFGNQ 195
           9*****************************445555544.....578****************************************** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           +Da+Efl++ +d++++++                  l+ +++ + +++ ++l+ ++F+g l+s++kcl+c+ vs +++p ld++l+++ 
   Q: 196  EDAHEFLQYTVDAMQKAC------------------LNGSNKLDRHTQATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKA 266
           ******************..................3344567789999**************************************** PP
   S: 179  keetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts 267
            +     s++++Le+f+k+e+l+gen y+c+kckk + a+k++++++ ++vL+l LkRf    ++    ki k v++p+ Ld++p++++
   Q: 267  AQ-----SVNKALEQFVKPEQLDGENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRF----ANFTGGKIAKDVKYPEYLDIRPYMSQ 346
           **.....9***************************************************....668889******************** PP
   S: 268  peekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkr 337
           p+ +   + +Y L+av+vH+G +++ GHY++y+k ++g W++++Ds V++++  +vl+   ++aYvlfY r
   Q: 347  PNGE---PIIYVLYAVLVHTGfNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLS---QQAYVLFYIR 411
           9977...8**************************************************...********87 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MTIVDKASES SDPSAYQNQP GSSEAVSPGD MDAGSASWGA VSSLNDVSNH TLSLGPVPGA 60
VVYSNSSVPD KSKPSPQKDQ ALGDGIAPPQ KVLFPSEKIC LKWQQTHRVG AGLQNLGNTC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTTGAACAA TGACCATAGT TGACAAAGCT TCTGAATCTT CAGACCCATC AGCCTATCAG 60
AATCAGCCTG GCAGCTCCGA GGCGGTCTCA CCTGGAGACA TGGATGCGGG TTCTGCCAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000401	Aegilops tauschii	38.91	1.00e-70	261.00
IUUC-Aml-002303	Ailuropoda melanoleuca	89.92	0.00e+00	1850.00
IUUC-Apl-003459	Anas platyrhynchos	44.26	0.00e+00	788.00
IUUC-Aca-004440	Anolis carolinensis	54.76	0.00e+00	1049.00
IUUC-Ago-007836	Ashbya gossypii	26.44	2.00e-34	140.00
IUUC-Ame-011358	Astyanax mexicanus	65.97	0.00e+00	671.00
IUUC-Bta-012803	Bos taurus	76.78	0.00e+00	1774.00
IUUC-Bol-015996	Brassica oleracea	43.31	1.00e-81	297.00
IUUC-Bra-016634	Brassica rapa	43.31	5.00e-82	299.00
IUUC-Cja-019199	Callithrix jacchus	75.65	0.00e+00	1682.00
IUUC-Cfa-020597	Canis familiaris	90.03	0.00e+00	2063.00
IUUC-Cpo-021945	Cavia porcellus	72.37	0.00e+00	1694.00
IUUC-Csa-023485	Chlorocebus sabaeus	76.31	0.00e+00	1634.00
IUUC-Cho-024575	Choloepus hoffmanni	76.38	0.00e+00	1028.00
IUUC-Dre-028442	Danio rerio	64.31	0.00e+00	651.00
IUUC-Dno-029673	Dasypus novemcinctus	78.38	0.00e+00	1915.00
IUUC-Dor-030518	Dipodomys ordii	64.57	2.00e-125	444.00
IUUC-Ete-033088	Echinops telfairi	61.23	0.00e+00	1028.00
IUUC-Eca-033579	Equus caballus	81.25	0.00e+00	1837.00
IUUC-Eeu-034511	Erinaceus europaeus	56.57	0.00e+00	1006.00
IUUC-Fca-035792	Felis catus	84.99	0.00e+00	1827.00
IUUC-Fal-037075	Ficedula albicollis	44.01	0.00e+00	868.00
IUUC-Gga-040504	Gallus gallus	44.23	0.00e+00	841.00
IUUC-Gma-044075	Glycine max	47.88	1.00e-84	308.00
IUUC-Ggo-044798	Gorilla gorilla	71.31	0.00e+00	1400.00
IUUC-Hsa-046072	Homo sapiens	76.23	0.00e+00	1626.00
IUUC-Hvu-047620	Hordeum vulgare	41.25	1.00e-73	271.00
IUUC-Itr-048078	Ictidomys tridecemlineatus	80.61	0.00e+00	1975.00
IUUC-Lch-049867	Latimeria chalumnae	69.68	0.00e+00	956.00
IUUC-Loc-052621	Lepisosteus oculatus	63.91	0.00e+00	694.00
IUUC-Laf-054330	Loxodonta africana	92.35	0.00e+00	1269.00
IUUC-Mcc-054900	Macaca mulatta	96.70	0.00e+00	775.00
IUUC-Meu-056877	Macropus eugenii	53.16	0.00e+00	719.00
IUUC-Mga-059501	Meleagris gallopavo	41.60	0.00e+00	773.00
IUUC-Mvi-060547	Microbotryum violaceum	45.62	1.00e-80	294.00
IUUC-Mmr-060864	Microcebus murinus	79.10	0.00e+00	1928.00
IUUC-Mdo-062395	Monodelphis domestica	64.12	0.00e+00	1558.00
IUUC-Mmu-064236	Mus musculus	69.55	0.00e+00	1584.00
IUUC-Mlu-067091	Myotis lucifugus	77.97	0.00e+00	1718.00
IUUC-Nle-069004	Nomascus leucogenys	75.19	0.00e+00	1657.00
IUUC-Opr-071170	Ochotona princeps	60.71	0.00e+00	1105.00
IUUC-Ont-071832	Oreochromis niloticus	61.05	0.00e+00	646.00
IUUC-Oan-073711	Ornithorhynchus anatinus	60.17	0.00e+00	1369.00
IUUC-Ocu-074596	Oryctolagus cuniculus	95.51	0.00e+00	1038.00
IUUC-Oga-088641	Otolemur garnettii	79.24	0.00e+00	1878.00
IUUC-Oar-089760	Ovis aries	73.50	0.00e+00	1640.00
IUUC-Ptr-091445	Pan troglodytes	75.93	0.00e+00	1639.00
IUUC-Pan-092484	Papio anubis	75.78	0.00e+00	1568.00
IUUC-Psi-093277	Pelodiscus sinensis	57.04	0.00e+00	1164.00
IUUC-Pma-094651	Petromyzon marinus	37.93	2.00e-56	212.00
IUUC-Pfo-096469	Poecilia formosa	66.94	0.00e+00	650.00
IUUC-Pab-097794	Pongo abelii	74.80	0.00e+00	1504.00
IUUC-Pva-103238	Pteropus vampyrus	72.49	0.00e+00	1532.00
IUUC-Rno-105068	Rattus norvegicus	69.60	0.00e+00	1593.00
IUUC-Sha-106713	Sarcophilus harrisii	65.35	0.00e+00	1585.00
IUUC-Smo-108763	Selaginella moellendorffii	47.73	1.00e-80	292.00
IUUC-Sar-113340	Sorex araneus	84.99	0.00e+00	1101.00
IUUC-Tgu-117149	Taeniopygia guttata	43.96	0.00e+00	867.00
IUUC-Tru-117776	Takifugu rubripes	65.57	5.00e-176	611.00
IUUC-Tsy-118974	Tarsius syrichta	76.18	0.00e+00	1815.00
IUUC-Tni-120774	Tetraodon nigroviridis	68.36	6.00e-173	600.00
IUUC-Tbe-128006	Tupaia belangeri	71.93	3.00e-155	543.00
IUUC-Ttr-128764	Tursiops truncatus	68.26	0.00e+00	1486.00
IUUC-Vvi-131535	Vitis vinifera	46.35	2.00e-86	314.00
IUUC-Xtr-132544	Xenopus tropicalis	58.33	0.00e+00	646.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence