iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-053933

Ensembl Protein ID

ENSLAFP00000008373.3

UniProt Accession

G3T4S1; G3T4S1_LOXAF

Protein Name

Uncharacterized protein

Gene Name

IFIH1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000009997.3	ENSLAFT00000009996.3	ENSLAFP00000008373.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/CARD	5.40e-42	142.6	111	182

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/CARD

   S: 2    deeyrlllstlqdrvrklLdvtdvldkylseflleeekelilaaaetkgnmqaaelLLktLvqkegWfrefl 73
           ++e ++ll++lq++++++L+v+dvld++++  ll+ e++ ++ aae+ gn++++++LLk++vqk +Wf++fl
   Q: 111  HDECLQLLNLLQPTLVDKLLVRDVLDECVANNLLTTEDRSRISAAENHGNESGVRELLKRIVQKDNWFSTFL 182
           89********************************************************************96 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MSNGCSLDKS FRYLISCFRV RLKMYIQVEP VLDYLTFLPA DLKEQIQKTA ATTGNIHAVE 60
LLLSNLEKGS WPLGWTREFM EALQQAGNPL AARYMNPDLT DLPSPSSENA HDECLQLLNL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGAATG GGTGTTCCTT AGACAAGAGT TTCCGGTATC TCATCTCGTG CTTCAGGGTC 60
AGACTGAAAA TGTACATCCA GGTGGAGCCA GTGCTGGACT ACCTGACATT CCTGCCAGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0862--Zinc

Interpro

IPR031964--CARD_dom
IPR011029--DEATH-like_dom
IPR006935--Helicase/UvrB_N
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR021673--RLR_CTR

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51789--RLR_CTR

Pfam

PF16739--CARD_2
PF00271--Helicase_C
PF04851--ResIII
PF11648--RIG-I_C-RD

SMART

SM00487--DEXDc
SM00490--HELICc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0003677--F:DNA binding
GO:0003725--F:double-stranded RNA binding
GO:0016817--F:hydrolase activity, acting on acid anhydrides
GO:0043021--F:ribonucleoprotein complex binding
GO:0003727--F:single-stranded RNA binding
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0039530--P:MDA-5 signaling pathway
GO:0032727--P:positive regulation of interferon-alpha production
GO:0032728--P:positive regulation of interferon-beta production
GO:0016925--P:protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001336	Ailuropoda melanoleuca	82.33	0.00e+00	1616.00
IUUC-Apl-003900	Anas platyrhynchos	60.84	0.00e+00	1177.00
IUUC-Aca-005329	Anolis carolinensis	58.60	0.00e+00	1008.00
IUUC-Ame-011305	Astyanax mexicanus	48.61	0.00e+00	874.00
IUUC-Bta-012361	Bos taurus	80.88	0.00e+00	1557.00
IUUC-Bci-013674	Botrytis cinerea	25.42	1.70e+00	28.10
IUUC-Cja-018760	Callithrix jacchus	82.20	0.00e+00	1580.00
IUUC-Cfa-020321	Canis familiaris	80.31	0.00e+00	1559.00
IUUC-Cpo-022450	Cavia porcellus	76.90	0.00e+00	1524.00
IUUC-Cre-022916	Chlamydomonas reinhardtii	32.23	6.00e-12	66.60
IUUC-Csa-024194	Chlorocebus sabaeus	84.24	0.00e+00	1594.00
IUUC-Cho-024364	Choloepus hoffmanni	74.32	0.00e+00	1053.00
IUUC-Cgl-026385	Colletotrichum gloeosporioides	24.42	8.00e-25	109.00
IUUC-Dre-028305	Danio rerio	55.79	0.00e+00	713.00
IUUC-Dno-029831	Dasypus novemcinctus	82.47	0.00e+00	1644.00
IUUC-Dor-030410	Dipodomys ordii	74.60	0.00e+00	1188.00
IUUC-Ete-032950	Echinops telfairi	74.07	0.00e+00	638.00
IUUC-Eca-034279	Equus caballus	83.51	0.00e+00	1617.00
IUUC-Eeu-034678	Erinaceus europaeus	77.51	0.00e+00	1538.00
IUUC-Fca-035618	Felis catus	84.53	0.00e+00	972.00
IUUC-Fal-037106	Ficedula albicollis	68.74	0.00e+00	973.00
IUUC-Fso-038398	Fusarium solani	27.11	7.00e-32	133.00
IUUC-Gmo-038598	Gadus morhua	50.72	0.00e+00	685.00
IUUC-Ggr-039898	Gaeumannomyces graminis	22.41	8.90e-01	29.60
IUUC-Gga-040467	Gallus gallus	60.12	0.00e+00	1156.00
IUUC-Gac-042316	Gasterosteus aculeatus	48.91	0.00e+00	836.00
IUUC-Ggo-045461	Gorilla gorilla	83.46	0.00e+00	1575.00
IUUC-Hsa-045771	Homo sapiens	83.27	0.00e+00	1573.00
IUUC-Itr-048762	Ictidomys tridecemlineatus	80.84	0.00e+00	1531.00
IUUC-Lch-049913	Latimeria chalumnae	65.70	0.00e+00	901.00
IUUC-Loc-052768	Lepisosteus oculatus	54.18	0.00e+00	991.00
IUUC-Mcc-054695	Macaca mulatta	84.24	0.00e+00	1595.00
IUUC-Meu-056829	Macropus eugenii	73.21	0.00e+00	1124.00
IUUC-Mga-059205	Meleagris gallopavo	60.30	0.00e+00	1149.00
IUUC-Mvi-060497	Microbotryum violaceum	32.24	4.00e-16	81.30
IUUC-Mmr-060703	Microcebus murinus	82.89	0.00e+00	1572.00
IUUC-Mdo-063079	Monodelphis domestica	70.66	0.00e+00	1411.00
IUUC-Mmu-064066	Mus musculus	78.19	0.00e+00	1587.00
IUUC-Mpu-066261	Mustela putorius furo	80.86	0.00e+00	1574.00
IUUC-Mlu-068196	Myotis lucifugus	80.43	0.00e+00	1547.00
IUUC-Nfi-068405	Neosartorya fischeri	25.27	2.00e-24	108.00
IUUC-Nle-069479	Nomascus leucogenys	79.86	0.00e+00	1535.00
IUUC-Opr-070717	Ochotona princeps	73.16	0.00e+00	1130.00
IUUC-Ont-071702	Oreochromis niloticus	47.11	0.00e+00	853.00
IUUC-Oan-073639	Ornithorhynchus anatinus	65.88	0.00e+00	1171.00
IUUC-Ocu-074521	Oryctolagus cuniculus	82.63	0.00e+00	1607.00
IUUC-Ola-086351	Oryzias latipes	45.91	0.00e+00	805.00
IUUC-Oga-088539	Otolemur garnettii	79.75	0.00e+00	1538.00
IUUC-Oar-090186	Ovis aries	80.60	0.00e+00	1541.00
IUUC-Ptr-090575	Pan troglodytes	79.57	0.00e+00	1529.00
IUUC-Pan-092371	Papio anubis	84.24	0.00e+00	1593.00
IUUC-Psi-093072	Pelodiscus sinensis	63.42	0.00e+00	1229.00
IUUC-Pma-094345	Petromyzon marinus	45.17	1.00e-98	353.00
IUUC-Pfo-096401	Poecilia formosa	52.96	0.00e+00	682.00
IUUC-Pab-097623	Pongo abelii	82.30	0.00e+00	1565.00
IUUC-Pca-100993	Procavia capensis	78.63	0.00e+00	1352.00
IUUC-Pva-102227	Pteropus vampyrus	78.02	0.00e+00	1469.00
IUUC-Pgr-103529	Puccinia graminis	28.25	8.00e-32	133.00
IUUC-Rno-105198	Rattus norvegicus	77.38	0.00e+00	1571.00
IUUC-Sha-107622	Sarcophilus harrisii	72.93	0.00e+00	1422.00
IUUC-Sar-113625	Sorex araneus	69.37	0.00e+00	737.00
IUUC-Sre-115121	Sporisorium reilianum	29.79	2.40e-01	32.00
IUUC-Tgu-117486	Taeniopygia guttata	58.03	0.00e+00	1113.00
IUUC-Tru-118445	Takifugu rubripes	46.44	0.00e+00	822.00
IUUC-Tsy-119512	Tarsius syrichta	80.06	0.00e+00	1494.00
IUUC-Tni-120711	Tetraodon nigroviridis	46.67	0.00e+00	849.00
IUUC-Tre-122194	Trichoderma reesei	25.33	1.00e-18	89.70
IUUC-Tbe-127644	Tupaia belangeri	72.44	0.00e+00	1368.00
IUUC-Ttr-128989	Tursiops truncatus	77.49	0.00e+00	1539.00
IUUC-Uma-129440	Ustilago maydis	25.53	1.30e+00	29.60
IUUC-Vpa-130587	Vicugna pacos	75.83	0.00e+00	1243.00
IUUC-Xtr-132127	Xenopus tropicalis	53.83	0.00e+00	1011.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence