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Tag Content
UUCD2 ID IUUC-Ocu-074193
UUCD1 version UUC-OrC-01020
Ensembl Protein ID ENSOCUP00000003197.3
UniProt Accession G1SK77; G1SK77_RABIT
Genbank Protein ID ENSOCUP00000003197
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAGW02024760
Gene Name USP8
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSOCUG00000003686.3 ENSOCUT00000003687.3 ENSOCUP00000003197.3
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 2.10e-109 365.8 747 1077
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           tGl+NlgNtCYmNS+LQcL n p l++++++  ++ ++n++n  ++kge+++++  ++++lw+++ +++sp++++ +++k++ +f g
   Q: 747  TGLRNLGNTCYMNSILQCLCNAPHLADYFNRnCYQDDINRSNLLGHKGEVAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQFAG 833
           7*****************************9899***************************************************** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeee...dkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfl 170
           y+qqD+qE+l fl+d+l+e+l+k +n ++++ee++   d+ ++ ++a++k+k+ n+s+i+ lFqgq+ks+++cl+c+++s ++e f+
   Q: 834  YSQQDSQELLLFLMDGLHEDLNKADNRKRHKEENNdhlDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFM 920
           *********************9855555555444411145566667***************************************** PP
   S: 171  dlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpl 257
           +lslp+ + +++   +lqdcL+ f+kee+l+++n++yc++c++++++ kk++++klP+vL +hLkRfs++ + ++ +k++++v+fpl
   Q: 921  YLSLPLASTSKC---TLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGR-WK-QKLQTSVDFPL 1002
           ***********9...******************************************************996.55.6********** PP
   S: 258  e.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYk 336
           e Ldls++++ p+++    kkY+L++v +H+G+l++GHY+ay+kn  ++ W++fdD++V+ ++ ++v++   s aY+lfY+
   Q: 1003 EsLDLSQYVIGPKNN---LKKYNLFSVSNHYGGLDGGHYTAYCKNAARQrWFKFDDHEVSDISVSSVKS---SAAYILFYT 1077
           ***********9988...69*************************88888*******************...********8 PP
   
Organism Oryctolagus cuniculus
Protein Sequence
(Fasta)
MPAVASVPKE LYLSSSLKDL NKKTEVKPEK ISTKSYVHSA QKIFKAAEEC RLDRDEERAY 60
VLYMKFVTVY NLIKKRPDFK QQQDYFHSIL GPANIKKAIE EAERLSESLK LRYEEAEVRK 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ocu-074193|DUB,USP|Oryctolagus cuniculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGAAAAGATA CATTTACTGA AGCATAGCAT TCATTGTGAA AATAGGAAAG TAAAAATTAT 60
TCATCATGCC TGCTGTGGCT TCAGTTCCTA AAGAACTCTA CCTCAGTTCT TCACTTAAAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ocu-074193|DUB,USP|Oryctolagus cuniculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR001394--Peptidase_C19_UCH
IPR001763--Rhodanese-like_dom
IPR015063--USP8_dimer
IPR018200--USP_CS
IPR028889--USP_dom
PROSITE

PS50206--RHODANESE_3
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
Pfam

PF00581--Rhodanese
PF00443--UCH
PF08969--USP8_dimer
SMART

SM00450--RHOD
Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0019897--C:extrinsic component of plasma membrane
GO:0030496--C:midbody
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0007032--P:endosome organization
GO:0000281--P:mitotic cytokinesis
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process
KEGG ocu:100351436
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001661 Ailuropoda melanoleuca 88.75 0.00e+00 1818.00
IUUC-Apl-003226 Anas platyrhynchos 70.26 0.00e+00 1452.00
IUUC-Aca-004936 Anolis carolinensis 67.85 0.00e+00 1309.00
IUUC-Ago-007959 Ashbya gossypii 35.62 6.00e-55 209.00
IUUC-Acl-008102 Aspergillus clavatus 31.32 1.00e-50 195.00
IUUC-Afl-008604 Aspergillus flavus 31.04 1.00e-49 191.00
IUUC-Afu-009001 Aspergillus fumigatus 31.11 9.00e-50 192.00
IUUC-Ani-009291 Aspergillus nidulans 31.16 2.00e-49 191.00
IUUC-Ang-009844 Aspergillus niger 32.43 6.00e-49 189.00
IUUC-Aor-010098 Aspergillus oryzae 31.04 6.00e-49 189.00
IUUC-Ate-010585 Aspergillus terreus 31.64 7.00e-49 189.00
IUUC-Ame-011029 Astyanax mexicanus 59.44 3.00e-71 261.00
IUUC-Bta-013008 Bos taurus 88.06 0.00e+00 1801.00
IUUC-Bol-015281 Brassica oleracea 38.21 9.00e-47 181.00
IUUC-Bra-017228 Brassica rapa 39.10 1.00e-48 187.00
IUUC-Cel-018482 Caenorhabditis elegans 33.82 2.00e-51 197.00
IUUC-Cja-019173 Callithrix jacchus 89.00 0.00e+00 1836.00
IUUC-Cfa-021243 Canis familiaris 88.54 0.00e+00 1817.00
IUUC-Cpo-021522 Cavia porcellus 86.95 0.00e+00 1773.00
IUUC-Cre-022582 Chlamydomonas reinhardtii 44.35 1.00e-81 296.00
IUUC-Csa-023616 Chlorocebus sabaeus 89.24 0.00e+00 1542.00
IUUC-Cho-024381 Choloepus hoffmanni 76.98 0.00e+00 1523.00
IUUC-Cin-025287 Ciona intestinalis 49.87 3.00e-98 353.00
IUUC-Csv-026253 Ciona savignyi 47.90 7.00e-87 315.00
IUUC-Cne-026821 Cryptococcus neoformans 39.89 2.00e-74 274.00
IUUC-Dre-028440 Danio rerio 64.56 0.00e+00 742.00
IUUC-Dno-029039 Dasypus novemcinctus 87.29 0.00e+00 1837.00
IUUC-Dor-031043 Dipodomys ordii 96.12 1.00e-132 468.00
IUUC-Dse-031463 Dothistroma septosporum 28.36 1.00e-41 165.00
IUUC-Dme-032089 Drosophila melanogaster 45.17 6.00e-84 305.00
IUUC-Ete-033040 Echinops telfairi 76.19 0.00e+00 1443.00
IUUC-Eca-033449 Equus caballus 88.99 0.00e+00 1830.00
IUUC-Eeu-034693 Erinaceus europaeus 96.12 2.00e-131 463.00
IUUC-Fca-035794 Felis catus 98.32 0.00e+00 926.00
IUUC-Fal-037322 Ficedula albicollis 79.09 0.00e+00 875.00
IUUC-Gmo-038584 Gadus morhua 66.73 0.00e+00 662.00
IUUC-Gga-041188 Gallus gallus 82.21 0.00e+00 907.00
IUUC-Gac-041850 Gasterosteus aculeatus 74.00 0.00e+00 737.00
IUUC-Ggo-045565 Gorilla gorilla 89.27 0.00e+00 1855.00
IUUC-Hsa-046438 Homo sapiens 89.18 0.00e+00 1853.00
IUUC-Itr-048883 Ictidomys tridecemlineatus 92.29 0.00e+00 1865.00
IUUC-Kpa-049321 Komagataella pastoris 33.24 6.00e-49 189.00
IUUC-Lch-050485 Latimeria chalumnae 83.14 0.00e+00 871.00
IUUC-Loc-052769 Lepisosteus oculatus 76.60 0.00e+00 764.00
IUUC-Lma-053021 Leptosphaeria maculans 32.75 4.00e-53 203.00
IUUC-Laf-053432 Loxodonta africana 81.36 0.00e+00 1690.00
IUUC-Mcc-055823 Macaca mulatta 89.09 0.00e+00 1852.00
IUUC-Meu-056099 Macropus eugenii 97.03 6.00e-164 571.00
IUUC-Mla-059089 Melampsora laricipopulina 39.88 2.00e-71 265.00
IUUC-Mga-059739 Meleagris gallopavo 82.03 0.00e+00 902.00
IUUC-Mvi-060559 Microbotryum violaceum 40.84 5.00e-77 283.00
IUUC-Mmr-061158 Microcebus murinus 87.35 0.00e+00 1789.00
IUUC-Mdo-061801 Monodelphis domestica 78.73 0.00e+00 1546.00
IUUC-Mmu-063665 Mus musculus 83.10 0.00e+00 1686.00
IUUC-Mpu-066738 Mustela putorius furo 88.27 0.00e+00 1779.00
IUUC-Mlu-067307 Myotis lucifugus 85.61 0.00e+00 1758.00
IUUC-Nfi-068410 Neosartorya fischeri 31.39 4.00e-50 193.00
IUUC-Nle-069314 Nomascus leucogenys 88.91 0.00e+00 1846.00
IUUC-Opr-070378 Ochotona princeps 84.31 0.00e+00 1286.00
IUUC-Ont-071545 Oreochromis niloticus 73.80 0.00e+00 764.00
IUUC-Oan-073537 Ornithorhynchus anatinus 75.22 0.00e+00 1496.00
IUUC-Ola-086622 Oryzias latipes 75.20 0.00e+00 740.00
IUUC-Oga-088271 Otolemur garnettii 86.61 0.00e+00 1761.00
IUUC-Oar-090431 Ovis aries 88.10 0.00e+00 1809.00
IUUC-Ptr-091339 Pan troglodytes 88.91 0.00e+00 1894.00
IUUC-Pan-091783 Papio anubis 82.48 0.00e+00 929.00
IUUC-Psi-093187 Pelodiscus sinensis 66.04 2.00e-160 559.00
IUUC-Pma-094626 Petromyzon marinus 58.23 2.00e-142 498.00
IUUC-Pfo-096463 Poecilia formosa 75.86 0.00e+00 755.00
IUUC-Pab-097645 Pongo abelii 89.00 0.00e+00 1842.00
IUUC-Pva-103222 Pteropus vampyrus 82.20 0.00e+00 862.00
IUUC-Pgr-103408 Puccinia graminis 35.66 1.00e-53 205.00
IUUC-Ptt-103699 Puccinia triticina 45.80 7.00e-68 252.00
IUUC-Pte-104348 Pyrenophora teres 28.83 3.00e-39 157.00
IUUC-Pyt-104711 Pyrenophora triticirepentis 31.11 9.00e-51 195.00
IUUC-Rno-105510 Rattus norvegicus 83.47 0.00e+00 1719.00
IUUC-Sce-106166 Saccharomyces cerevisiae 35.26 3.00e-51 197.00
IUUC-Sha-106879 Sarcophilus harrisii 85.51 0.00e+00 946.00
IUUC-Sja-107836 Schizosaccharomyces japonicus 36.29 4.00e-48 185.00
IUUC-Sar-113019 Sorex araneus 81.11 0.00e+00 1683.00
IUUC-Sre-115031 Sporisorium reilianum 37.33 6.00e-69 256.00
IUUC-Ssc-116334 Sus scrofa 89.37 0.00e+00 1828.00
IUUC-Tgu-117062 Taeniopygia guttata 78.98 0.00e+00 880.00
IUUC-Tru-117908 Takifugu rubripes 59.82 0.00e+00 1176.00
IUUC-Tsy-118867 Tarsius syrichta 82.30 0.00e+00 1005.00
IUUC-Tni-120206 Tetraodon nigroviridis 55.34 0.00e+00 1058.00
IUUC-Tme-127144 Tuber melanosporum 40.00 3.00e-78 286.00
IUUC-Tbe-127877 Tupaia belangeri 85.88 1.00e-86 314.00
IUUC-Ttr-128580 Tursiops truncatus 84.15 0.00e+00 1689.00
IUUC-Uma-129340 Ustilago maydis 37.63 9.00e-71 262.00
IUUC-Vpa-130541 Vicugna pacos 87.47 0.00e+00 1796.00
IUUC-Xtr-132161 Xenopus tropicalis 58.93 0.00e+00 1188.00
IUUC-Xma-134271 Xiphophorus maculatus 73.41 0.00e+00 755.00
IUUC-Yli-134561 Yarrowia lipolytica 35.92 7.00e-60 225.00
Created Date 25-Jun-2017

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