iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089748

Ensembl Protein ID

ENSOARP00000008029.1

UniProt Accession

W5PC68; W5PC68_SHEEP

Genbank Protein ID

ENSOARP00000008029

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01053161

Gene Name

WDSUB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000007484.1	ENSOART00000008148.1	ENSOARP00000008029.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	6.20e-25	87.3	402	473
E3 adaptor/Cullin RING/DCX/DWD	7.60e-42	139.7	98	125
UBD/Beta-Prp	6.20e-56	189.9	7	219

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 1    evpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceen 72
           e+p+ef+CpI+ elM+dPv++++G++y+++++e w++++++t+P+t+  l++  l+Pn tl+  i++w++e 
   Q: 402  EIPDEFICPITRELMKDPVIASDGYSYEKEAMENWISKKKRTSPMTNLVLSSMILTPNRTLKMAINRWLSET 473
           69******************************************************************9986 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 4    dsvtclaf.sd.tllvsGsdDgtikvWD 29
           ++v+ ++f +d t lvsG+ Dgt+ +W+
   Q: 98   SPVRVCRFsPDsTCLVSGASDGTVVLWN 125
           78999****999***************9 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtl 90
           tl +h+++v +  +f  ++sllat s d+ti+++++++ +    + l+ h+ +v +++fsp+g il+++s+D+t  +wd+++g+++ ++
   Q: 7    TLADHDDDVNC-CAF--SSSLLATCSLDKTIRLYSLSDFTEvpYSPLKFHTYAVHCCCFSPSGHILASCSTDGTTVLWDVQNGQILAVM 92
           66666666655.899..9*******************966578999******************************************* PP
   S: 91   kghe.dsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgg 178
           ++ + + v+ ++fsp++  lvsG +d t+ +w+ ++++  + + s++dg+    +++p gnl+v+Gs  + + +Wd   +++l+  +  
   Q: 93   EQPSgSPVRVCRFSPDSTCLVSGASDGTVVLWNAQSYKLHR-CASVKDGSLVACAFSPPGNLFVTGSSCGDLTVWDD-KMRCLHNEKA- 178
           *765267***************************9999998.******99999999999*****************9.5678887776. PP
   S: 179  htdsvyslsfdsng..........kelvsgsldgtvklwdl 209
           h+  +++ +f+s+           ++l+s+++d ++k+w +
   Q: 179  HDLGITCCDFSSQPvpggeeglqfFQLASCGQDCQIKIWVI 219
           ************99*************************76 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MVKLIHTLAD HDDDVNCCAF SSSLLATCSL DKTIRLYSLS DFTEVPYSPL KFHTYAVHCC 60
CFSPSGHILA SCSTDGTTVL WDVQNGQILA VMEQPSGSPV RVCRFSPDST CLVSGASDGT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTGAAAC TGATTCACAC ATTAGCAGAT CATGATGATG ATGTCAACTG CTGTGCCTTC 60
TCCTCTTCCC TCTTGGCCAC TTGCTCCTTG GACAAAACAA TTCGCCTATA TTCCCTGAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR011047--Quinoprotein_ADH-like_supfam
IPR001660--SAM
IPR013761--SAM/pointed
IPR003613--Ubox_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50105--SAM_DOMAIN
PS51698--U_BOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07647--SAM_2
PF04564--U-box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00454--SAM
SM00504--Ubox
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

oas:101111522

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001614	Ailuropoda melanoleuca	89.31	0.00e+00	884.00
IUUC-Apl-003529	Anas platyrhynchos	74.42	0.00e+00	747.00
IUUC-Aca-004257	Anolis carolinensis	70.29	0.00e+00	700.00
IUUC-Ame-011357	Astyanax mexicanus	52.60	1.00e-118	420.00
IUUC-Bta-013032	Bos taurus	96.44	0.00e+00	955.00
IUUC-Cja-018743	Callithrix jacchus	87.84	0.00e+00	874.00
IUUC-Cfa-021197	Canis familiaris	88.89	0.00e+00	884.00
IUUC-Cpo-022279	Cavia porcellus	86.58	0.00e+00	864.00
IUUC-Csa-023954	Chlorocebus sabaeus	88.68	0.00e+00	877.00
IUUC-Cho-025083	Choloepus hoffmanni	72.03	2.00e-153	535.00
IUUC-Cin-025786	Ciona intestinalis	34.82	4.00e-82	298.00
IUUC-Dre-028087	Danio rerio	57.20	2.00e-145	509.00
IUUC-Dno-028919	Dasypus novemcinctus	89.52	0.00e+00	892.00
IUUC-Dor-031112	Dipodomys ordii	83.44	0.00e+00	830.00
IUUC-Ete-032405	Echinops telfairi	85.17	5.00e-176	609.00
IUUC-Eca-033254	Equus caballus	87.84	0.00e+00	873.00
IUUC-Eeu-034545	Erinaceus europaeus	84.07	0.00e+00	813.00
IUUC-Fca-035482	Felis catus	89.94	0.00e+00	886.00
IUUC-Fal-036976	Ficedula albicollis	61.40	9.00e-159	553.00
IUUC-Gmo-039213	Gadus morhua	54.78	3.00e-137	481.00
IUUC-Gga-040561	Gallus gallus	73.22	0.00e+00	732.00
IUUC-Gac-041471	Gasterosteus aculeatus	57.20	2.00e-139	489.00
IUUC-Ggo-045503	Gorilla gorilla	88.68	0.00e+00	880.00
IUUC-Hsa-045910	Homo sapiens	88.89	0.00e+00	882.00
IUUC-Itr-048214	Ictidomys tridecemlineatus	86.74	0.00e+00	688.00
IUUC-Loc-052307	Lepisosteus oculatus	57.99	7.00e-165	573.00
IUUC-Laf-053587	Loxodonta africana	88.26	0.00e+00	876.00
IUUC-Mcc-055679	Macaca mulatta	88.68	0.00e+00	881.00
IUUC-Meu-055962	Macropus eugenii	69.18	0.00e+00	634.00
IUUC-Mga-059652	Meleagris gallopavo	72.80	0.00e+00	737.00
IUUC-Mmr-060943	Microcebus murinus	85.15	0.00e+00	847.00
IUUC-Mdo-062592	Monodelphis domestica	80.83	0.00e+00	806.00
IUUC-Mmu-063577	Mus musculus	78.99	0.00e+00	791.00
IUUC-Mpu-066422	Mustela putorius furo	88.24	0.00e+00	875.00
IUUC-Mlu-067250	Myotis lucifugus	88.89	0.00e+00	875.00
IUUC-Nle-069517	Nomascus leucogenys	88.47	0.00e+00	879.00
IUUC-Opr-070776	Ochotona princeps	86.37	0.00e+00	857.00
IUUC-Ont-071821	Oreochromis niloticus	58.02	6.00e-151	526.00
IUUC-Oan-073706	Ornithorhynchus anatinus	81.32	0.00e+00	803.00
IUUC-Ocu-074766	Oryctolagus cuniculus	80.00	0.00e+00	779.00
IUUC-Obr-076354	Oryza brachyantha	49.32	1.00e-18	87.40
IUUC-Ola-086531	Oryzias latipes	56.90	2.00e-146	512.00
IUUC-Oga-088388	Otolemur garnettii	86.37	0.00e+00	860.00
IUUC-Ptr-090616	Pan troglodytes	88.40	0.00e+00	872.00
IUUC-Pan-091769	Papio anubis	87.83	1.00e-180	625.00
IUUC-Psi-093334	Pelodiscus sinensis	77.15	0.00e+00	722.00
IUUC-Pma-094383	Petromyzon marinus	49.61	2.00e-136	479.00
IUUC-Pfo-096832	Poecilia formosa	52.38	3.00e-139	488.00
IUUC-Pab-098139	Pongo abelii	88.21	0.00e+00	712.00
IUUC-Pca-100523	Procavia capensis	83.91	9.00e-162	563.00
IUUC-Pva-102286	Pteropus vampyrus	88.89	0.00e+00	851.00
IUUC-Rno-104831	Rattus norvegicus	80.46	0.00e+00	811.00
IUUC-Sha-107499	Sarcophilus harrisii	82.18	0.00e+00	816.00
IUUC-Sar-113389	Sorex araneus	85.12	0.00e+00	825.00
IUUC-Tgu-116769	Taeniopygia guttata	71.49	0.00e+00	704.00
IUUC-Tru-118774	Takifugu rubripes	55.14	1.00e-141	496.00
IUUC-Tsy-119595	Tarsius syrichta	76.03	5.00e-174	603.00
IUUC-Tni-119850	Tetraodon nigroviridis	56.14	1.00e-144	506.00
IUUC-Tbe-127938	Tupaia belangeri	78.69	1.00e-139	488.00
IUUC-Ttr-128193	Tursiops truncatus	91.27	0.00e+00	770.00
IUUC-Vpa-130275	Vicugna pacos	92.03	0.00e+00	904.00
IUUC-Xtr-131982	Xenopus tropicalis	62.63	5.00e-172	597.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence