iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054070

UUCD1 version

UUC-LoA-00318

Ensembl Protein ID

ENSLAFP00000007823.2

UniProt Accession

G3T3I9; G3T3I9_LOXAF

Protein Name

Uncharacterized protein

Gene Name

SOCS6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000009337.2	ENSLAFT00000009335.2	ENSLAFP00000007823.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	3.80e-17	62.2	488	535

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 2    sklwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedy 52
            ++ +++ ++rSLq+LCR++Ir++++++ +   +kLPLP+++kdYL++++y
   Q: 488  TNPVSRFMQVRSLQYLCRFVIRQYTRIDLI---QKLPLPNKMKDYLQEKHY 535
           5788999********************888...***************997 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MKKISLKTFR KSFNLNKSKE ETDFMVVQQP SLASDFGKDD SLFGSCYGKD MASCDINSED 60
EKSGKTRSKS ESLMGTLKRR LSAKQKQRGK GGAPSGSSVD EDTFSSSSAP IVFKDVRAQR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAGAAAA TTAGTCTTAA AACCTTCCGG AAATCTTTTA ACTTGAATAA AAGTAAAGAA 60
GAAACTGATT TCATGGTAGT ACAACAACCT TCACTTGCCA GTGATTTTGG GAAAGATGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028421--SOCS6
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0001772--C:immunological synapse
GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0050868--P:negative regulation of T cell activation
GO:0010498--P:proteasomal protein catabolic process
GO:0016567--P:protein ubiquitination
GO:0040008--P:regulation of growth

KEGG

lav:100670207

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001911	Ailuropoda melanoleuca	92.71	0.00e+00	919.00
IUUC-Apl-004035	Anas platyrhynchos	88.41	0.00e+00	879.00
IUUC-Aca-004782	Anolis carolinensis	86.75	0.00e+00	844.00
IUUC-Ame-011790	Astyanax mexicanus	68.13	0.00e+00	641.00
IUUC-Bta-012579	Bos taurus	95.22	6.00e-109	387.00
IUUC-Bol-015843	Brassica oleracea	28.77	2.50e-02	33.10
IUUC-Cel-018643	Caenorhabditis elegans	33.59	1.00e-11	62.80
IUUC-Cja-019528	Callithrix jacchus	92.71	0.00e+00	968.00
IUUC-Cfa-020678	Canis familiaris	91.40	0.00e+00	928.00
IUUC-Cpo-021947	Cavia porcellus	91.40	0.00e+00	960.00
IUUC-Csa-023935	Chlorocebus sabaeus	92.52	0.00e+00	935.00
IUUC-Cho-024477	Choloepus hoffmanni	88.79	0.00e+00	930.00
IUUC-Cin-025413	Ciona intestinalis	68.24	3.00e-66	245.00
IUUC-Csv-026247	Ciona savignyi	67.47	6.00e-65	241.00
IUUC-Dre-027636	Danio rerio	68.84	0.00e+00	632.00
IUUC-Dno-029048	Dasypus novemcinctus	93.08	0.00e+00	942.00
IUUC-Dor-030401	Dipodomys ordii	88.81	0.00e+00	891.00
IUUC-Ete-033116	Echinops telfairi	49.11	2.00e-57	215.00
IUUC-Eca-033825	Equus caballus	92.15	0.00e+00	888.00
IUUC-Fca-036253	Felis catus	90.28	0.00e+00	832.00
IUUC-Fal-037614	Ficedula albicollis	88.41	0.00e+00	879.00
IUUC-Fox-037898	Fusarium oxysporum	27.16	1.40e-02	33.10
IUUC-Gmo-038928	Gadus morhua	68.45	0.00e+00	662.00
IUUC-Gga-040177	Gallus gallus	88.04	0.00e+00	876.00
IUUC-Gac-042263	Gasterosteus aculeatus	69.98	0.00e+00	693.00
IUUC-Ggo-045288	Gorilla gorilla	92.15	0.00e+00	938.00
IUUC-Hsa-046409	Homo sapiens	92.15	0.00e+00	935.00
IUUC-Itr-048996	Ictidomys tridecemlineatus	90.65	0.00e+00	895.00
IUUC-Lch-050354	Latimeria chalumnae	84.33	0.00e+00	864.00
IUUC-Loc-052319	Lepisosteus oculatus	79.85	0.00e+00	808.00
IUUC-Mcc-055045	Macaca mulatta	92.52	0.00e+00	934.00
IUUC-Meu-055917	Macropus eugenii	89.91	0.00e+00	949.00
IUUC-Mga-059273	Meleagris gallopavo	88.22	0.00e+00	872.00
IUUC-Mmr-061597	Microcebus murinus	91.96	0.00e+00	932.00
IUUC-Mdo-062492	Monodelphis domestica	64.72	8.00e-109	386.00
IUUC-Mmu-063374	Mus musculus	81.97	0.00e+00	813.00
IUUC-Mpu-065967	Mustela putorius furo	87.66	0.00e+00	868.00
IUUC-Mlu-067532	Myotis lucifugus	90.65	0.00e+00	894.00
IUUC-Nle-069373	Nomascus leucogenys	92.34	0.00e+00	935.00
IUUC-Opr-070873	Ochotona princeps	88.22	0.00e+00	926.00
IUUC-Ont-072498	Oreochromis niloticus	70.30	0.00e+00	728.00
IUUC-Oan-072943	Ornithorhynchus anatinus	72.32	2.00e-98	352.00
IUUC-Ocu-073870	Oryctolagus cuniculus	91.96	0.00e+00	930.00
IUUC-Ola-086866	Oryzias latipes	89.86	4.00e-105	373.00
IUUC-Oga-089057	Otolemur garnettii	89.91	0.00e+00	889.00
IUUC-Oar-089841	Ovis aries	61.75	1.00e-166	579.00
IUUC-Ptr-091054	Pan troglodytes	92.15	0.00e+00	934.00
IUUC-Pma-094253	Petromyzon marinus	44.34	4.00e-100	358.00
IUUC-Pfo-097179	Poecilia formosa	64.51	7.00e-176	610.00
IUUC-Pab-097702	Pongo abelii	92.34	0.00e+00	936.00
IUUC-Pca-100671	Procavia capensis	91.78	1.00e-137	483.00
IUUC-Rno-106044	Rattus norvegicus	79.53	0.00e+00	803.00
IUUC-Sha-107139	Sarcophilus harrisii	88.76	0.00e+00	865.00
IUUC-Smo-108823	Selaginella moellendorffii	33.96	3.40e-02	32.00
IUUC-Sly-111748	Solanum lycopersicum	46.15	2.80e-01	30.00
IUUC-Ssc-115343	Sus scrofa	91.03	0.00e+00	920.00
IUUC-Tgu-117061	Taeniopygia guttata	88.22	0.00e+00	878.00
IUUC-Tni-119829	Tetraodon nigroviridis	66.54	0.00e+00	644.00
IUUC-Ttr-129148	Tursiops truncatus	89.91	0.00e+00	868.00
IUUC-Vpa-130780	Vicugna pacos	88.60	0.00e+00	852.00
IUUC-Vvi-130966	Vitis vinifera	32.69	5.80e-02	31.20
IUUC-Xtr-132513	Xenopus tropicalis	80.19	0.00e+00	827.00
IUUC-Xma-133904	Xiphophorus maculatus	68.21	0.00e+00	667.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence